• Product# ML1001 
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Electronic Stimulator

The ML1001 Electronic Stimulator is designed to provide electrical stimulation in physiological and pharmacological research experiments. The Electronic Stimulator provides options for single pulse, paired pulse, pulse train and repeat pulse operation. Biphasic stimuli are also supported.  The stimulator is equipped with a booster amplifier to allow field stimulation with a maximum output of 50V. Input terminals also allow signal mixing and modulation with an external signal.

Stimulation Trigger
Main Interval

(1) START

A) MANUAL switch (front panel)
B) START INPUT (rear)
Input pulse: +3.5 V or over, 10 μs or over
Input impedance: 10 kilohms or over
C) Short-circuit of KEY terminal (rear) and E terminal


2) STOP

A) MANUAL switch (front panel)
B) STOP INPUT (rear)
Input pulse: +3.5 V or over, 10 μs or over
Input impedance: 10 kilohms and over

3) SET CYCLES
  • Setting range: 1 ms to 9990 s, within ±0.1%
  • Unit: ms, s
  • Number: 3 digits

4) CYCLES
  • Repeat count: 1 to 999
  • Continuous stimulation: when set to “run”

5) External trigger
  • TRIG LEVEL: 0 to +10 V continuous variable
  • Approx. 3 V when turned fully counterclockwise
  • Input impedance: 100 kilohms or over

Stimulation Waveform Setup

1) DELAY

  • Setting range: 0 to 99.9 s, ±1%, within ±2 μs
  • Unit: μs, ms, s
  • Number: 3 digits

2) INTERVAL
  • Setting range: 100 μ to 999s, within ±0.1%
  • Unit: μs, ms, s
  • Number: 3 digits

3) DURATION
  • Setting range: 10 μ to 99.9 s, ±1%, within ±2 μs
  • Unit: μs, ms, s
  • Number: 3 digits

4) TRAIN
  • Setting range: 1 to 999
  • Continuous operation when set to “run”

Stimulation Output

1) Output polarity and OFF

  • Polarity switch: Positive/negative polarity (No effect on MODULATION or MIXING polarity)
  • OFF: No output to ISOLATOR or OUTPUT

2) MODULATION
  • Amplitude: Depends on amplitude of external signal including polarity (Max. ±10 V)
  • Linearity: within ±7% at ±1 V to ±10 V
  • Input impedance: 100 kilohms or over
  • No modulation in relation to MIXING waveform

3) MIXING
  • Mixing method: Analog addition
  • Mixing voltage range: 0 to ±10 V (Voltage after mixing: max. ±10 V)
  • Linearity: within ±7% at ±1 V to ±10 V
  • Input impedance: 100 kilohms or over

4) DC
  • Output voltage: Direct current 0 to ±10 V
  • Direct current 0 to ±50 V when ±50 V output is selected

5) Isolator output (to ISO)
Pin: 1, 2 +15 V
3 –15 V
4 Signal output
5 Range data
6 E
7 Range data synchronizing clock
8 Void
9 Void
10 Void
The fourth signal is not output fivefold when ±50 V output is selected.
(±10 V)

6) Output
  • Linearity: 0 to ±1 V, within ±50 mV, Within ±1 V to ±10 V ±5%
  • Output impedance: 100 kilohms or less (at RL ≥ 2 kilohms)
  • Output waveform: 3 μs or less both rising and falling
  • Excessive deviation: 5% or less

7) ±50 V output
  • Linearity: 0 to ±5 V, within ±100 mV, ±5 V to ±50 V, within ±5%
  • Output impedance: 10 ohms or less
  • Output waveform: 7 μs or less both rising and falling
  • Excessive deviation: 10% or less
  • Maximum output current: 400 mA or over

Synchronized Output Signal

1) Output signal name

  • MAIN INTERVAL
  • SET CYCLES END
  • EXT TRIG
  • DELAY
  • INTERVAL
  • TRAIN END

2) Output signal
  • Amplitude: +5 V
  • Pulse width: approx. 500 μs
  • Rising: 3 μs or less
  • Output impedance: 1 kilohm or less

Language: English

Power Source
  • Voltage: AC 110 V, 220 V or 240 V ±10 %
  • (Changed voltage range by the connector)
  • Frequency: 50/60 Hz
  • Power input: 70 VA

Environment
  • Main operating environment: Laboratory

Operating Environment
  • Temperature: 10 to 40°C
  • Humidity: 30 to 90%
  • Atmospheric pressure: 70 to 106 kPa

Storage Environment
  • Temperature: –20 to 60°C
  • Humidity: 10 to 95%
  • Atmospheric pressure: 70 to 106 kPa

Durability
  • 6 years (based on self-certification of company data)

Installation
  • Indoor installation type

Safety Standards
  • Applicable safety standards:IEC 60601-1 IEC 60601-1-2 :2001
  • Type of protection against electrical shock: Class I
  • Degree of protection against electrical shock where attached: B applied parts
  • Degree of protection against harmful ingress or liquids: IPX0 (devices w/o special protection)
  • Mode of operation: Continuous operation
  • Voltage endurance: AC 1500 V, 1 minute
  • Leakage current: 100 μA or less for both earth leakage and enclosure leakage
  • Insulation resistance: 50 megohms or over (DC 500 V)
  • Mechanical strength of stimulator: Compliant with impact NS7231-5.7, vibration NS7231-5.8

Dimensions and Weight
  • Dimensions: 430 (W) x 98 (H) x 300 (D) mm
  • Weight: Approx. 8.3 kg

Electromagnetic Compatibility
  • IEC 60601-1-2 :2001
  • EMC level (CISPR11) Class B
For a single stimulation source:
  • Neurophysiology
    • Patch clamping
    • Extracellular recording
    • Nerve fiber – action potentials
  • Muscle and isolated myocyte studies
    • Skeletal Muscle
    • Smooth Muscle
    • Cardiac Muscle
  • Provides stimulation options including:
    • Train stimulation - single pulse, pair pulse and train pulse
    • Biphasic pulse stimulation
    • Field stimulation with a maximum output of ±50 V and 400 mA (built-in booster amplifier) with any stimulation waveform
  • Generates mixed and modulated stimulus waves when combined with an external signal
  • Fine adjustment of output voltage up to 10 V
  • USB communication to PC
  • Output terminal for connection with the ML1101 Stimulus Isolator that:
    • Provides constant voltage or constant current output
    • Provides stimulus of positive or negative polarity
    • Provides excellent input and output linearity
    • Features a built-in over current alarm
    • Displays the amount of power that goes through the isolator