Intracellular Low Cost Electrometer

Overview:

The IE-251A-V Intracellular Low Cost Electrometer is a low cost version of the research grade IE-210-V Intracellular Electrometer. The important features required for low noise, drift free recording from glass microelectrodes have been retained in this lower cost model. The IE-251A-V is easy to use and is an excellent choice for student teaching laboratories. The IE-251A-V includes a very small active headstage, essentially the same as used with the IE-210-V. Epoxy-sealed construction affords maximum resistance to saline corrosion. Its small size and low mass permit easy mounting in a micropositioner. The supplied probe connects directly to the probe input, however, an electrode holder is not included with the IE-251A-V and must be purchased separately.

Includes:

• IE-251A-V Intracellular Low Cost Electrometer
• 2510W Headstage for IE-251A-V
• Electrode Probe

 

IE-251A-V Intracellular Low Cost Electrometer Electrode Holders:
The IE-251A-V is supplied with a probe, however, an electrode holder is not included with the IE-251A-V. Please purchase a holder separately based on the outer diameter of your electrode glass.

Note: These electrode holders are available for purchase separately.

• ESP/W-F10N E Series Electrode Holder (Str, Ag-AgCl Pellet & Wire, 1.0 mm)
• ESP/W-F12N E Series Electrode Holder (Str, Ag-AgCl Pellet & Wire, 1.2 mm)
• ESP/W-F15N E Series Electrode Holder (Str, Ag-AgCl Pellet & Wire, 1.5 mm)
• ESP/W-F20N E Series Electrode Holder (Str, Ag-AgCl Pellet & Wire, 2.0 mm)
• ESP-F10N E Series Electrode Holder (Str, Ag-AgCl Pellet, 1.0 mm)
• ESP-F12N E Series Electrode Holder (Str, Ag-AgCl Pellet, 1.2 mm)
• ESP-F15N E Series Electrode Holder (Str, Ag-AgCl Pellet, 1.5 mm)
• ESP-F20N E Series Electrode Holder (Str, Ag-AgCl Pellet, 2.0 mm)

Note: Please specify line operating voltage (V = 115 or 220 VAC)

Features:

• Fixed gains of x1 and x10
• Capacitance Compensation neutralizes input capacitance for up to 50 pF
• Junction potentials of up to ±200 mV are nulled with the DC Position control
• Electrode Test provides convenient electrode resistance check
• Push button operated Buzz produces oscillations at pipette tip to facilitate cell impalement
• Convenient Probe Test port permits fast check of amplifier performance

Current Injection:
The injection circuitry of the IE-251A-V allows simultaneous stimulation and recording through microelectrode resistances up to 1000 MΩ in two ranges. Voltages at the Stimulus Input are converted to constant currents applied to the electrode. The steady state and transient components of the current injection artifact are nulled with the DC and transient balance controls. The corrected signal is viewed at the single-ended bridge output. Electrode resistance is read from the DC balance ten-turn dial.

Overdrive Indicators:
Two visual indicators call attention to overload conditions:

• Input Overdrive is illuminated whenever the probe input voltage exceeds ±1 V,caused by either excessive current through the microelectrode or an open circuit (open or blocked electrode)
• Current Overdrive warns of excessive voltage (>50 V) applied to the Stimulus Input

Applications:

The Intracellular Low Cost Electrometer can are designed for intracellular current clamping.

For more information see the Intracellular Recordings, Neurophysiology, Patch & Voltage Clamping and Evoked Potentials applications pages.

 

Specifications: