Langendorff System (Constant Pressure or Flow)

Overview:

The ML870B2 Langendorff System (Constant Pressure or Flow) is designed for the perfusion of small animal hearts such as mouse, rat and guinea pig. It is quick to set up and easy to use.

Components:

• ML870 PowerLab 8/30 (includes LabChart and Scope software)
• MLS260 LabChart Pro software
• ML176 Langendorff Apparatus and Thermostat Controller
• ML172 Minipuls-3 Peristaltic Pump
• ML175 STH Pump Controller
• ML221 Bridge Amps (2)
• MLT844 Physiological Pressure Transducer (2)
• ML136 Animal Bio Amp
• MLA1210 Spring Clip Electrodes (Set of 3)
• ML312 T-Type Pod
• MLT1401 T-Type Implantable Thermocouple Probe (IT-18)
• MLA2001 Langendorff Transducer Accessory Kit, which includes:
      Connection Tubing (Luer Male Lock to Female, 300mm)
      Luer 4-Way Male Lock Stopcocks
      Luer Male Lock Plugs
      Luer Male Lock Slip Connectors
      Transducer Bracket

Data Acquisition and Analysis:
The PowerLab 8/30 is shipped with ADInstruments software (LabChart and Scope), associated manuals and cables. The ML870/P is also supplied with LabChart Pro software which includes all the ADInstruments LabChart Modules(excluding GLP). LabChart Modules provide application specific data acquisition, analysis and display features.

The modules currently available include:

• Circadian Analysis (Windows) new
• Dose Response (Windows) new
• Peak Analysis (Windows) new
• Blood Pressure (Windows)
• ECG Analysis (Windows)
• Heart Rate Variability (Windows & Macintosh)
• Spike Histogram (Windows & Macintosh)
• Metabolic (Windows & Macintosh)
• Video Capture (Macintosh)
• Cardiac Output (Windows)
• DMT Normalization (Windows & Macintosh)

In purchasing this system containing LabChart Pro entitles the purchaser to 5 years of FREE LabChart Pro software upgrades and updates. Purchasers are also entitled to any ADInstruments modules released during this 5 year period (excludes GLP software).

For more information see the LabChart Pro page or contact your nearest ADInstruments representative.

Features:

• A simpler, more effective solution for constant perfusate flow or pressure using a Minipuls-3 Peristaltic Pump and ADInstruments STH Pump Controller.
• The STH Pump Controller is the key to the system as it eliminates the need for elevated reservoirs and allows continuous recording of flow rate without an expensive flowmeter.
• A robust and compact apparatus. The perfusate reservoir includes two thermostatically controlled compartments which allow different perfusate solutions to be changed easily.
• The versatile, 8-channel PowerLab 8/30 data acquisition system that can simultaneously monitor multiple parameters from your isolated heart experiments. These include left ventricular pressure, rate of ventricular pressure change, perfusate pressure and flow rate, developed pressure, cardiac electrical activity, temperature and others. The PowerLab analog output may also be used to control the frequency of pulses from an external stimulator.
• Two Physiological Pressure Transducers and Bridge Amplifiers connected to a PowerLab to record perfusate pressure and left ventricular pressure.
• The Animal Bio Amp to amplify the cardiac electrical activity
• The T-type Pod and T-type Implantable Thermocouple Probe (IT-18) for temperature monitoring

Applications:

The Langendorff System (Constant Pressure or Flow) is designed for the perfusion of small animal hearts such as mouse, rat and guinea pig. More information can be found within the Langendorff Heart application page.

Specifications: