The Langendorff System is designed for the perfusion of small animal hearts such as mouse, rat and guinea pig. It is quick to set up and easy to use.
While traditional Langendorff apparatus uses complex, delicate glassware and elevated reservoirs for constant pressure perfusion, the ADInstruments Langendorff System provides a simpler, more effective solution for constant perfusate flow or pressure using a
Minipuls-3 Peristaltic Pump and ADInstruments
STH Pump Controller. The STH Pump Controller is the key to the system as it eliminates the need for elevated reservoirs and allows continuous recording of flow rate without an expensive flowmeter.
The Langendorff apparatus is robust and compact. The perfusate reservoir includes two thermostatically controlled compartments which allow different perfusate solutions to be changed easily.
The versatile, 8-channel
PowerLab 8/30 data acquisition system can simultaneously monitor multiple parameters from your isolated heart experiments. These include left ventricular pressure, rate of ventricular pressure change, perfusate pressure and flow rate, developed pressure, cardiac electrical activity, temperature and others. The PowerLab analog output may also be used to control the frequency of pulses from an external stimulator.
With the Langendorff System, perfusate pressure and left ventricular pressure are recorded using two
Physiological Pressure Transducers and
Bridge Amplifiers connected to a PowerLab. The cardiac electrical activity can be amplified using the
Animal Bio Amp and temperature monitored with the
T-type Pod and
T-type Implantable Thermocouple Probe (IT-18).
Components:
Data Acquisition and Analysis:
The PowerLab 8/30 is shipped with ADInstruments software (
LabChart and
Scope), associated manuals and cables. The ML870/P is also supplied with
LabChart Pro software which includes all the ADInstruments LabChart Modules (excluding GLP). LabChart Modules provide application specific data acquisition, analysis and display features.
The modules currently available include:
In purchasing this system containing LabChart Pro entitles the purchaser to 5 years of FREE LabChart Pro software upgrades and updates. Purchasers are also entitled to any ADInstruments modules released during this 5 year period (excludes GLP software).
For more information see the LabChart Pro page or contact your nearest ADInstruments representative.