Radnoti Langendorff Constant Pressure Non-recirculating

Overview:

The 120105EZ-V Radnoti Langendorff Constant Pressure Non-recirculating (pump driven) apparatus is ideal for a rat, guinea pig or small rabbit Langendorff heart preparation, which is perfused at constant perfusion pressure and is non-recirculating. As the system is configured for constant perfusion pressure, changes in resistance from the heart will result in flow variations that can be monitored via a flow meter. The apparatus has complete water jacketing including the perfusion tubing.

Components:

• Water-Jacketed 2-Liter Reservoir
• Water-Jacketed Bubble Trap
• Water-Jacketed Heart Chamber
• Aortic cannula
• Lab Stand Assembly clamp hardware
• Tubing Connector Kit
• Pre-assembled Water Jacketed Flex Tube Assembly
• Peristaltic Pump and Pump Head
• Radnoti 170051B Thermal Circulator Water Bath

With additional equipment left ventricular pressure or apical force using the built-in pulley system and coronary resistance can be measured. For experimentation that requires the heart to autoregulate pressure, please see Radnoti constant flow systems 120103EZ-V.

This Radnoti isolated perfused heart system for rats can also be purchased as a complete data acquisition and analysis system in the Rat Langendorff Constant Pressure Non-Recirculating System.

Ordering Information:
When ordering the 120103EZ apparatus please specify the mains power voltage.
Where V= 115 for 110-115 mains power and 220 for 220-240 mains power.

Note:
For countries with 115V power service, the Thermo circulator requires a 20 AMPS outlet
For countries with 220V power service, the Thermo circulator requires a 15 AMPS outlet.
 

Features:

Applications:

This type of system is often used for dose response studies in pharmacology.  This constant pressure Langendorff system uses a peristaltic pump to perfuse the heart and since pressure is held constant, changes in coronary resistance are detected as changes in flow.  By using multiple reservoirs or a syringe pump, different solutions or drug concentrations can be delivered to the heart and washed out.

For more information about this application visit the Langendorff Heart page.

Specifications: