MPVS-Ultra Single Segment Pressure-Volume Unit

Overview:

The 880-0168SS MPVS-Ultra Single Segment Pressure-Volume Unit can be used in the measurement of ventricular pressure and volume in mice and rats only. The unit provides pressure and volume measurements via BNC-BNC cables that connect directly to a PowerLab data acquisition unit from outputs including:

• Pressure 1
• Pressure 2
• Composite Volume
• Segment 1
• ECG
• Temperature and Cuvette (For diagnostic purposes)
• Segments 2 - 7 outputs are disabled by the software.

The MPVS-Ultra Single Segment Pressure-Volume Unit includes:

• US or European power cord, USB cable
• User manual and MPVS Ultra training CD
• MPVS Ultra Control software

Additional components purchased separately include:

• Pressure-volume catheters (see below for suitable catheters)
• 880-0170BNC Cable Kit
• 001-1056 PVAN Ultra Analysis Software
• 910-1049 Volume Calibration Cuvette (1.5 to 4.0 mm)
• 910-1048 Volume Calibration Cuvette (2 to 15 mm)
• 910-1060 Rho Calibration Cuvette Kit
• 880-0168U MPVS Ultra Upgrade (Converts SS Unit to MS Unit) for small and large animals
• MLA1052 Pressure Gauge kit which provides the necessary items to calibrate the pressure transducer

This unit is recommended for measuring ventricular pressure-volume in hearts from mice and rats using any of the following Single Segment Pressure-Volume catheters including:

• PVR-1030 Mouse PV Catheter (1F, 4E, 3mm) - Non Repair
• PVR-1035 Mouse PV Catheter (1F, 4E, 3.5mm) - Non Repair
• PVR-1045 Mouse PV Catheter (1F, 4E, 4.5mm) - Non Repair
• SPR-839 Mouse PV Catheter (1.4, 4E, 4.5mm)
• SPR-847 Rat PV Catheter (1.4F, 4E, 9mm)
• SPR-869 Rat PV Catheter (2F, 4E, 6mm)
• SPR-838 Rat PV Catheter (2F, 4E, 9mm)
• SPR-878 Rat PV Catheter (2F, 4E, 12mm)
• SPR-858 Rat PV Catheter (2F, 4E, 14mm)
• SPR-851 Rat PV Catheter (3F, 4E, 20mm)
• SPR-853 Mouse Dual PV Catheter (1.4F, 2P, 4E, 4mm)
• SPR-848 Mouse Dual PV Catheter (1.4F, 2P, 4E,4.5mm, Ap)
• SPR-864 Mouse Dual PV Catheter (1.4F, 2P, 4E,4.5mm, Car)
• SPR-901 Rat Dual PV Catheter (2F, 2P, 12mm, 4E)
• SPR-902 Rat Dual PV Catheter (2F, 2P, 12mm, 4E 9mm Ap)

The MPVS Ultra Single Segment Pressure-Volume Unit is included in ADInstruments PL3508B48/M MPVS Ultra Single Segment Foundation System for Mice and PL3508B48/R MPVS Ultra Single Segment Foundation System for Rats. The Pressure-Volume catheters listed above are to be purchased separately for use with these systems. For more information or assistance please contact your nearest ADInstruments representative.

 

Features:

• Analog outputs for two pressure signals and two volume outputs to easily integrate with PowerLab and LabChart.
• State-of-the-art technology
• Can be used with small animals
• Can be upgraded to  be used with large animals
  
• Flexible volume determination using selectable catheter segments
• Built-in volume calibration technique using volume calibration cuvettes
  
• Software-controlled user interface
• Adjustable gain settings to allow both in vivo and in vitro studies
• Dual pressure inputs
• Seamless integration with PowerLab and LabChart
• Compatible with all Millar Mikro-Tip P-V Catheters

Applications:

The MPVS Ultra™ Single Segment Pressure-Volume unit simultaneously and continuously measures high-fidelity left ventricular pressure and volume from the intact beating hearts of animals, from mice and rats. Common applications include:

• Baseline P-V loop analysis
• Occlusion P-V loop analysis
• Phenotyping gene manipulations
• Monitoring of cardiac failure or hypertrophy
• Cardiovascular remodeling
• Pharmacology and toxicology

To read more about this application see the Ventricular Pressure-Volume page.

Specifications: