Dual Channel Epithelial Voltage Clamp System
- Product# PL3508B78-V
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Overview:
The PL3508B78-V Dual Channel Epithelial Voltage Clamp System is designed for studies of epithelial transport and the electrical properties of tissues, using the EC-825A-V Dual Channel Epithelial Voltage Clamp (50 V compliance) and a suitable Ussing chamber (purchased separately). Measurements include transepithelial voltage, short circuit current and membrane resistance.
System Components:
- PL3508 PowerLab 8/35 (includes LabChart software)
- MLS260/7 LabChart Pro software
- PLA190 19 Inch Rack Adapter
- EC-825A-V Dual Channel Epithelial Voltage Clamp (50 V compliance)
Ordering Information:
When ordering the PL3508B78-V please specify the following.
Mains Power (V) = 115 for 110-115V or 220 for 220-240V
Ussing Chambers (purchased separately):
- U2500/A Dual Ussing Chamber w/O-Ring Insert 3.8 mm
- U2500/B Dual Ussing Chamber w/Pin Insert 3.8 mm
- U2500/C Dual Ussing Chamber w/Slotted Insert 1.6x7 mm 6 Pins
- U2500/M Dual Ussing Chamber w/Millicell Insert 12 mm
- U2500/S Dual Ussing Chamber w/Snapwell Insert 12 mm
- U2500/T Dual Ussing Chamber w/Transwell Insert 6.5 mm
Data Acquisition and Analysis:
The PowerLab 8/35 is shipped with ADInstruments LabChart software that provides data recording integrity, display and analysis features. The research system is also supplied with LabChart Pro software, which includes all the ADInstruments LabChart Modules (excluding GLP Client and Server). LabChart Modules provide application specific data acquisition, analysis and display features.
LabChart Pro also entitles the purchaser to 5 years of FREE LabChart Pro software upgrades and updates. Purchasers are also entitled to any LabChart Module released during this 5 year period (excludes GLP Client and Server).
For more information see the LabChart Pro page or contact your nearest ADInstruments representative.
Features:
- Differential voltage recordings are made with very high common mode rejection (CMR) providing accurate measurements free from the effects of common mode potential changes of a noisy environment.
- Membrane Resistance Measurement Circuit using a low frequency 2 Hz bipolar signal to avoid polarization of the membrane (ideal for monolayers).
- Three Clamp Speeds selection provide optimum recording conditions for a variety of applications, such as Fast mode (as fast as 10 µsec) for preparations with low access resistance (small tissues or monolayers) and Medium or Slow modes for stable, oscillation free clamping in larger tissues.
- Operating modes include voltage clamp, current clamp, voltmeter, and resistance.
- Independent Voltage and Current Commands.
- Internal DC Command (Hold) control for both Voltage clamp and Current clamp modes.
- The clamp can be operated by an external programmer, lab timer or computer - logic control of clamp mode and clamp command levels is possible as well as simultaneous mixing of external linear commands.
- Watertight Headstage with Model Membrane





