Patch Clamp Recording System with 5101-10G Headstage
- Product# PL3508B79/10-V
- Add to Quote Request
Overview:
The PL3508B79/10-V Patch Clamp Recording System with 5101-10G Headstage is suitable for measuring currents up to ±1 nA via the headstage in whole cell measurements and single channel studies. Microelectrodes or glass electrodes/micropipettes are not supplied. Other resistive-feedback headstages are also separately available for use with the PC-501A Patch Clamp Amplifier.
System Components:
- PL3508 PowerLab 8/35 (includes LabChart software)
- MLS260/7 LabChart Pro software
- PLA190 19 Inch Rack Adapter
- PC-501A/10-V Patch Clamp with 5101-10G Headstage
- 5101-10G Headstage for PC-501A/10-V (10 GOhm) (for recording single channel currents up to ±10 nA)
- MC-10G 10 GOhm Model Cell for PC-501A/10-V
- QSW-A15P Q Series Electrode Holder (Str, Port, Ag Wire, 1.5 mm)
Ordering Information:
When ordering the PL3508B79/10-V please specify the following.
Mains Power (V) = 115 for 110-115V or 220 for 220-240V
Accessories (purchased separately):
- Electrode Holders (selection based on the outer diameter of user’s glass electrode)
Headstages (purchased separately):
- 5101-100M Headstage for PC-501A/8-V (100 MOhm) (for recording currents up to ±100 nA, supplied with the PL3508B79/8-V Patch Clamp Recording System with 5101-100M Headstage or PC-501A/8-V Patch Clamp Amplifier with 5101-100M Headstage)
- 5101-01G Headstage for PC-501A/9-V (1 GOhm) (for recording currents up to ±10 nA, supplied with the PL3508B79/9-V Patch Clamp Recording System with 5101-01G Headstage or PC-501A/9-V Patch Clamp Amplifier with 5101-01G Headstage)
Data Acquisition and Analysis:
The PowerLab 8/35 is shipped with ADInstruments LabChart software that provides data recording integrity, display and analysis features. The research system is also supplied with LabChart Pro software, which includes all the ADInstruments LabChart Modules (excluding GLP Client and Server). LabChart Modules provide application specific data acquisition, analysis and display features.
LabChart Pro also entitles the purchaser to 5 years of FREE LabChart Pro software upgrades and updates. Purchasers are also entitled to any LabChart Module released during this 5 year period (excludes GLP Client and Server).
For more information see the LabChart Pro page or contact your nearest ADInstruments representative.
Features:
- Independent V-hold and I-hold circuitry (3 operating modes)
- V Clamp Mode: Input is clamped to a maximum of ±1 V. Commands are the sum of the holding voltage and any external input signals.
- Zero Current Mode: Bridges the voltage and current clamp modes. All commands are inactive except the junction zero, which functions in this case as an offset control for the electrode and tip potentials associated with the pipette.
- I Clamp Mode: In the current clamp mode, active commands are the current hold and any external command input signals, summed. Clamp stability is enhanced with the selection of three clamp speeds.
- Compensation Controls
- Voltage Offsets (including junction potentials): Automatically compensated with the auto zero or manually with the junction zero.
- Capacity Compensation: Paired controls; fast (0-5 µs), medium (0-2 ms) and slow (0-20 ms) compensate the current transient caused by a step command signal. Each pair has a separate control for amplitude and time constant.
- Series Resistance: Signal errors contributed by the electrode (access) resistance in whole cell recording are subtracted from the output with the series R comp control. The compensated resistance (0-100 MΩ) is read from a ten turn dial.
- Leak Subtract: Used to compensate leakage current due to the voltage drop across the seal (shunt) resistance.
- 4-pole low-pass Bessel filter
- Internally generated test signals
- Variable duration zap circuit
