Spike Histogram Module for Windows
- Model# MLS062/7
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Overview:
The MLS062/7 Spike Histogram Module for Windows provides neuroscientists in conjunction with our PowerLab systems, the ability to record and analyze extracellular spike data in real time and offline.
This module allows the user to quickly discriminate and analyze extracellular neural spike activity using two discrimination methods. Discriminated spikes can be viewed in specialized histogram windows including amplitude histogram, rate meter, peristimulus histogram, autocorrelogram and more.
Spike Histogram 2.0 Module requires a PowerLab system and LabChart 7.0.1 or later.
The Spike Histogram Module is also available as part of LabChart Pro. The LabChart Pro software package includes all LabChart Modules. Existing LabChart users and PowerLab system purchasers can upgrade to LabChart Pro at a special price. If you need more information please contact your ADInstruments Representative.
For more information download the Software Booklet (5.83 MB) or contact your nearest ADInstruments Representative.
Sample Applications:
Spike Histogram Module can be used for the analysis of extracellular spike recordings in studies including:
Features & Benefits:
- Advanced spike discrimination and data analysis in real time or after recording.
- Two discrimination methods
- Fast and easy template matching for spike discrimination or
- Freehand contour drawing for precise selection of spikes
- Automatic indication and examination of changes in neural firing rate.
- Multi-channel, multi-unit analysis allows comparison of any physiologic measures recorded
- Channel calculations displaying properties of the defined unit(s) such as frequency
- Spike Histogram Settings dialog allows
- Data source selection
- Extracted waveforms detection threshold, pretrigger and total trigger period
- Template matching options
- Spike units defined in the Discriminator View window can be used as an Event Source in Scope View. Spike triggered averaging can be performed by setting up averaging using time-based occurrence of spikes.
- Six specialized histogram windows:
- Rate Meter plots the spike firing rate against time
- Amplitude displays a histogram of spike amplitudes from different populations
- Interspike Interval displays a histogram of interspike intervals distribution
- Peristimulus Time Histograms examines changes in neural firing rates due to a repeated stimulus
- Autocorrelation Histogram detects periodicity in an individual unit or any inherent periodicity in spike
- Cross-correlation Histogram detects periodicity or temporal dependence of two physiologic parameters
- Ability to export data into NeuroExplorer® for further analysis of spike trains. NeuroExplorer provides an extensive set of spike train analysis options and histograms including burst analysis, spectral analysis and Poincaré maps.
Screenshots & Videos:
LabChart spike recording (top left) analysis using Spike Discriminator View (lower left) with individual spike units in Scope View (top right) and analysis using Autocorrelation Histogram (lower right).
Spike Histogram Discriminator view window. Scatter Plot of spikes contained within the current user-defined limits in Chart View window (dragging the limit lines refines the discrimination) (left). Overlay of whole individual spike shapes with selected unit of spikes from left pane colored red (right). Black bold line represents individual spike selected in left pane.
Spike Histogram Settings dialog.
Amplitude displays a histogram of amplitudes.
Interspike Interval displays a histogram of intervals between spikes.
Rate Meter Window plots the firing rate against time.
Peristimulus Time Histogram examines the changes in neural firing rates due to a repeated stimulus or event.
Autocorrelation Histogram detects periodicity in an individual unit or any inherent periodicity in spike.
Cross-correlation histogram detects periodicity or temporal dependence of two physiologic parameters.
Spike Histogram channel calculation dialog.
Spike units defined in Spike Histogram Discriminator Window can be used as an Event Source in LabChart Scope View.
Data from LabChart exported to NeuroExplorer software for extensive spike train analysis.
