Extracellular recordings that are supported include: single or multiple unit recordings, whole nerve recordings, field potentials, and epithelial voltage clamping.
Extracellular research measures and characterizes the electrical properties of cells and tissues, particularly neurons and neuronal tissue. Measurements are usually performed either in the extracellular fluid near the cell of interest, or non-invasively. These measurements can be divided into three main groups, which include single/multiple unit recordings, whole nerve recordings, and extracellular field potentials. Epithelial voltage clamping recording can also be classified under extracellular recordings.
Easily acquire and analyze extracellular potentials from nerves and brain slices, and seamlessly assess conscious neural activity, extracellular spikes, and extracelllular field potentials, by using a combination of the PowerLab 35 series and our extracellular neural amplifiers.
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In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of the event in LabChart, giving you even more flexibility and the ability to integrate your data streams in one place.
All our hardware is backed by the appropriate safety certification standards. More information on safety standards.
Designed for recording extracellular signals using an AC/DC Differential Amplifier with Active Headstage, which is compatible with either glass or metal microelectrodes.
A system for measuring epithelial transport signals from a single epithelial sample (tissue or cell layer). System includes the Epithelial Voltage Clamp (120 V compliance).
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Differential Amplifier with Active Headstage
An AC/DC single channel differential amplifier that is highly suited for extracellular recording using glass or metal microelectrodes.
4 Channel Extracellular Differential Amplifier
A four channel low noise, high input impedance, AC/DC differential pre-amplifier, which ideally suited for extracellular recordings.
Dual Channel Epithelial Voltage Clamp (50 V compliance)
For studies of epithelial transport and the electrical properties of tissue. Can also be purchased as part of the Dual Channel Epithelial Voltage Clamp System.
Epithelial Voltage Clamp (120 V compliance)
For studies of epithelial transport and the electrical properties of tissue. Can also be purchased as part of the Single Channel Epithelial Voltage Clamp System.
Self-contained Ussing Chamber Systems, available in single-channel and dual-channel models. Contact us using the Quote Request for Ussing Chamber pricing.
U2500, U9926, U2500/M, U2500/A, U2500/B, U2500/C, U2500/S, U2500/T, U9926/M, U9926/A, U9926/B, U9926/C, U9926/S, U9926/T
Self-Contained Ussing Chamber Inserts
Self-Contained Ussing Chamber Inserts, which include Culture Cups Inserts for adaptors (Snapwell, Millicell, Transwell) and Tissue Inserts (with O-Ring, Round with 5 Pins or Slotted with 6 pins...
The E Series Electrode Holders are used for interfacing various neurophysiological recording electrodes to suitable corresponding headstages of extracellular AC/DC pre-amplifiers, and...
E45W-F10VH, E45W-F12VH, E45W-F15VH, E45W-F20VH, ESP/W-F10N, ESP/W-F12N, ESP/W-F15N, ESP/W-F20N, ESP-F10N, ESP-F12N, ESP-F15N, ESP-F20N, ESW-F10V, ESW-F12V, ESW-F15V, ESW-F20V,
Engineered for precise, consistent, reliable data acquisition of a wide range of physiological signals. PowerLab gives you the reproducible data you need while meeting the strictest international standards.
Creates a platform allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots.
Neurophysiology Neuroscience
Neural circuits and networks
Neural transmission
Action or synaptic potentials
Extracellular recordings that are supported include: single or multiple unit recordings, whole nerve recordings, field potentials, and epithelial voltage clamping.
Fluid flow can be recorded in extracellular research.
Temperature can be recorded in extracellular research.
ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart analysis software and a PowerLab data acquisition unit you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.
Enabling Discovery
LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.
Data with Integrity
High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.
LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.
This data was recorded from an extracellular microelectrode. The resulting action potentials are analyzed using the Spike Histogram Add-On; a histogram of the amplitudes and other analyses for both units are displayed.
This is a common issue in electrophysiology as you are dealing with very small signals as well as high impedance and capacitance of electrodes. All of ADInstruments hardware is optimized with high-quality noise specifications, but it is always good to have a few other tricks up your sleeve to help in your setup.
Additional acquisition and analysis features and add-ons to support your Extracellular studies:
The Peak Analysis Module for LabChart provides automatic detection and analysis of multiple, non-overlapping, signal peaks.
Peak Analysis
MLS380/8
The Spike Histogram Module for LabChart provides the ability to record and analyze extracellular spike data in real time.
Spike Histogram
MLS062/8
Display, overlay, average and analyze periodic or evoked waveforms in real time. Ideal for finding that time from stimulus to response in repeated evoked potential recordings.
Scope View
Powerfully convert your time based signal to its component frequencies.
Spectrum
Neuroscience Fundamentals: Using Scope, Peak Analysis and Spike Histogram
Three of the most widely utilized and complimentary tools to LabChart all have one common...
Thank you for your interest in Extracellular. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
×Thank you for your interest in Extracellular. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
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