Perform Epithelial Voltage Clamping using our complete systems for accurate measurements of transepithelial voltage, short circuit current, and membrane resistance.
The Ussing chamber, which was invented by Hans Henriksen Ussing, is used for housing and sustaining living epithelial tissue or a monolayer of cells, while an appropriate epithelial amplifier and suitable electrodes are used to measure the electrical properties of the membrane. These electrical properties indicate and quantify the transport of ions, nutrients, and drugs across the tissue.
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In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of the event in LabChart, giving you even more flexibility and the ability to integrate your data streams in one place.
All our hardware is backed by the appropriate safety certification standards. More information on safety standards.
A system for measuring epithelial transport signals from a single epithelial sample (tissue or cell layer). System includes the Epithelial Voltage Clamp (120 V compliance).
A system for measuring epithelial transport signals simultaneously from two epithelial samples (tissue or cell layer). System includes the Dual Channel Epithelial Voltage Clamp (50 V compliance).
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Epithelial Voltage Clamp Amplifiers
Amplifiers designed to provide accurate measurements of transepithelial voltage, short circuit current and membrane resistance.
Self-Contained Dual Ussing Chamber Base Assembly
Designed to be used with a dual epithelial voltage clamp and suitable inserts for measuring two electrical membrane parameters of various epithelial tissues or cells.
Self-Contained Single Ussing Chamber Base Assembly
Designed to be used with an epithelial voltage clamp and a suitable insert for measuring a single electrical membrane parameter of various epithelial tissues or cells.
Self-Contained Ussing Chamber Inserts
Self-Contained Ussing Chamber Inserts, which include Culture Cups Inserts for adaptors (Snapwell, Millicell, Transwell) and Tissue Inserts (with O-Ring, Round with 5 Pins or Slotted with 6 pins...
Culture Cup w/Falcon Insert 9.0 mm
The U9924F-09 Culture Cup w/Falcon Insert 9.0 mm is for use with Ussing Chambers.
Culture Cup w/Millicell Insert 12 mm
The U9924M-12 Culture Cup w/Millicell Insert 12 mm is for use with Ussing Chambers.
Culture Cup w/Snapwell Insert 12 mm
The U9924S Culture Cup w/Snapwell Insert 12 mm is for use with Ussing Chambers.
Culture Cup w/Transwell Insert 6.5 mm
The U9924T-06 Culture Cup w/Transwell Insert 6.5 mm is for use with Ussing Chambers.
NaviCyte Vertical Ussing Chamber System
The NaviCyte Vertical Ussing Chamber System is designed to simultaneously maintain and run up to six Ussing chambers in a single holder. The holder is paired with suitable epithelial voltage clamp...
NaviCyte Vertical Ussing Chambers
This Ussing chamber series allows surgically excised tissue sections or a monolayer of cells (SnapwellTM) to be mounted, housed, and sustained between two compartments,...
NaviCyte Vertical Chamber Caps and Electrodes
Accessories that include caps and electrodes for NaviCyte Vertical Ussing Chambers that are used to measure epithelial electrophysiological parameters with suitable amplifiers.
A metal enclosure that can be used for converting any 35 series PowerLab into a rack mountable enclosure.
Engineered for precise, consistent, reliable data acquisition of a wide range of physiological signals. PowerLab gives you the reproducible data you need while meeting the strictest international standards.
Creates a platform allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots.
Data acquisition and analysis re-imagined. Make unique discoveries with unlimited freedom and flexibility.
Epithelial ion transport
Drug absorption
Transmucosal studies
Transmembrane conductance
Epithelial permeability
Gastrointestinal studies
Skin studies
A range of signals can be recorded from living epithelial tissue or a monolayer of cells:
Perform Epithelial Voltage Clamping using our complete systems for accurate measurements of transepithelial voltage, short circuit current, and membrane resistance.
Temperature can be recorded in Ussing research.
ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart or LabChart Lightning analysis software and a PowerLab data acquisition unit, you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.
Enabling Discovery
LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.
Data acquisition and analysis re-imagined. Make unique discoveries with unlimited freedom and flexibility. Try LabChart Lightning »
Data with Integrity
High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.
LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.
Recorded short-circuit current (Isc) from two epithelial tissues maintained Ussing chambers in response to a drug agonist and are superimposed via Scope View.
Here are some tips to ensure you get stable recordings of short-circuit currents:
Additional acquisition and analysis features and add-ons to support your Ussing studies:
The Dose Response Software Module allows analysis and graphical display of dose response type data recorded in LabChart.
Dose Response
MLS390/8
Pre-process incoming signals to detect cycles and analyze waveforms in real-time.
Cyclic Measurements
Display, overlay, average and analyze periodic or evoked waveforms in real time. Ideal for finding that time from stimulus to response in repeated evoked potential recordings.
Scope View
Our most powerful channel calculation allows you access to LabChart's calculation engine, allowing customized formulae, detection, and analysis.
Arithmetic
Our simple two point calibration tool makes converting Voltage units to known measurement units quick and simple.
Units Conversion
Create a custom protocol to control stimulation frequency and timing of pulse trains.
Stimulator Dialog
Neuroscience Fundamentals: Using Scope, Peak Analysis and Spike Histogram
Three of the most widely utilized and complimentary tools to LabChart all have one common...
Thank you for your interest in Ussing. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
×Thank you for your interest in Ussing. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
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