Ussing

The Ussing chamber, which was invented by Hans Henriksen Ussing, is used for housing and sustaining living epithelial tissue or a monolayer of cells, while an appropriate epithelial amplifier and suitable electrodes are used to measure the electrical properties of the membrane. These electrical properties indicate and quantify the transport of ions, nutrients, and drugs across the tissue.

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Recorded short-circuit current (Isc) from two epithelial tissues maintained Ussing chambers in response to a drug agonist and are superimposed via Scope View.

Products and Solutions

Record multiple
signals at one time

Simple, streamlined systems
you can build upon

Mix and match products for a custom solution

Integrate all your
data streams
in one place

In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of the event in LabChart, giving you even more flexibility and the ability to integrate your data streams in one place.

All our hardware is backed by the appropriate safety certification standards. More information on safety standards.

Complete System

Single Channel Epithelial Voltage Clamp System

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A system for measuring epithelial transport signals from a single epithelial sample (tissue or cell layer). System includes the Epithelial Voltage Clamp (120 V compliance).

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Single Channel Epithelial Voltage Clamp System

PL3508B77-V

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Dual Channel Epithelial Voltage Clamp System

Quote Request

A system for measuring epithelial transport signals simultaneously from two epithelial samples (tissue or cell layer). System includes the Dual Channel Epithelial Voltage Clamp (50 V compliance).

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Dual Channel Epithelial Voltage Clamp System

PL3508B78-V

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Components & Related Products

Typical Ussing Chamber Studies

Epithelial ion transport

Drug absorption

Transmucosal studies

Transmembrane conductance

Epithelial permeability

Gastrointestinal studies

Skin studies

Signals Supported

A range of signals can be recorded from living epithelial tissue or a monolayer of cells:

Extracellular Recordings

Perform Epithelial Voltage Clamping using our complete systems for accurate measurements of transepithelial voltage, short circuit current, and membrane resistance.

Temperature

Temperature can be recorded in Ussing research.

Flexible Data Acquisition

ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart analysis software and a PowerLab data acquisition unit you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

Enabling Discovery

LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.

LabChart and Ussing

PowerLab

Data with Integrity

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.

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All your Ussing analysis in one place

LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.

Recorded short-circuit current (Isc) from two epithelial tissues maintained Ussing chambers in response to a drug agonist and are superimposed via Scope View.