Aortic Stenosis results from the aortic valve not opening completely, which causes an increase in aortic resistance (afterload). The increase in aortic resistance causes left ventricular pressure to increase greatly during ejection. As a result, end-systolic volume increases since less blood is pumped out of the ventricle. Since less blood is pumped, the end-systolic volume will also increase slightly, decreasing stroke volume. This activates the Frank-Starling mechanism, increasing the contraction's force to maintain stroke volume.
Aortic stenosis will cause PV loops to shift up and to the right.
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