Kaha telemetry machines

For the wireless recording of a variety of biological signals in small animals, ADInstruments offers our telemetry brand, Kaha Sciences.

Kaha Sciences sets the new standard in quality and power for implantable, wireless telemetry in rats and mice. Kaha Telemetry is the best option for research scientists, allowing you to record continuous data from freely moving animals across extended periods with accuracy, reliability, and sensitivity.

Kaha telemeters can record true high-fidelity signals such as ventricular and arterial pressures, sympathetic nerve activity (SNA), biopotentials (e.g. ECG, EMG & EEG), tissue oxygen, and optogenetics stimulating and recording.

Power

Patented wireless power technology allows for higher sampling rates (2 kHz), improved time resolutions, and opens the door for the unique use of more complicated and power intensive technologies such as oxygen sensors and high quality Millar Mikro-Tip™ sensors (rat pressure telemeters).

Quality

Rat pressure telemeters incorporate a gold standard Millar Mikro-Tip™ catheter containing a solid-state sensor at the catheter tip. This provides customers with the ability and confidence to measure long-term, highly accurate and sensitive recordings from intracardiac through to intracranial pressures.

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The Benefits of Telemetry

The use of telemetry within animal research is beneficial for a wide array of reasons and is a recommended industry practice for improved animal welfare.

  • Conscious – Anesthesia affects most physiological control systems and can significantly confound your results. Telemetry allows data to be collected from conscious animals after they have recovered from surgery and enables cognitive and behavioral studies not possible under anesthesia.
  • Unrestrained – Restraining animals induces stress which affects normal physiological functions and the data recorded. Telemetry allows data collection from animals in their home cage without the stress induced by the presence of researchers or handling.
  • Long-term – By monitoring physiological functions over days, weeks or months, researchers can study biological rhythms and follow the development of pathology as it occurs. Within animal design, telemetry strengthens the statistical power of a study and can reduce group sizes.

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Kaha Sciences Buyers Guide

Kaha

Kaha Sciences is a brand of ADInstruments NZ Ltd. ADInstruments gives researchers access to a trusted global sales and support network with over 35 years of industry experience.

Surgical Instruction And Webinar Video Series

Our online Kaha Sciences Support Section contains surgical videos and recordings of application and product webinars to help you best use and care for your Kaha telemetry system.

See video series

System Configuration

A typical telemetry setup requires one telemeter of your choice and one SmartPad or tBase per animal. Each laboratory will just require one Configurator in order to configure all your Kaha equipment.

  1. Select and pair transmission frequencies between SmartPads and their Telemeters using Configurator.
  2. Surgically implant the Telemeter.
  3. Connect the SmartPad to a PowerLab and/or Instrument Interface via BNC.

You are then ready to analyze your data using LabChart 8 or LabChart Lightning.

Rat Signal Options:

Pressure

Biopotentials
(ie., ECG, EMG, EEG)

Sympathetic nerve
activity (SNA)

Tissue oxygen

Temperature (output
in all telemeters)

Optogenetics

Mouse Signal Options:

Biopotentials

Index of activity

Proven within the research community

Kaha catheters have been tested and validated as an accurate and trustworthy combination for research.

  • Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration Connar Stanley James Westgate, Christina Kamp-Jensen, Ida Marchen Egerod Israelsen, Trine Toft-Bertelsen, Jonathan Henry Wardman, Christian Ahm Jensen, Bjarne Styrishave, Nanna MacAulay, Rigmor Højland Jensen and Sajedeh Eftekhari British Journal of Pharmacology, 2023.

    Correction of medication nonadherence results in better seizure outcomes than dose escalation in a novel preclinical epilepsy model of adherence A. Cameron Hill, Kyle E. Thomson, Thomas G. Newell, and H. Steve White Epilepsia, vol. 60, no. 3, 2019, pp. 475–84 

    Hypertensive Response to Ischemic Stroke in the Normotensive Wistar Rat Pratik Thakkar, Ailsa McGregor, Paul Alan Barber, Julian F.R. Paton, Carolyn Barrett, and Fiona McBryde Stroke, vol. 50, no. 9, 2019, pp. 2522–30. 

  • Neuroprosthetic Baroreflex controls haemodynamics after spinal cord injury Jordan W. Squair, Matthieu Gautier, Lois Mahe, Jan Elaine Soriano, Andreas Rowald, Arnaud Bichat, Newton Cho, Mark A. Anderson, Nicholas D. James, Jerome Gandar, Anthony V. Incognito, Giuseppe Schiavone, Zoe K. Sarafis, Achilleas Laskaratos, Kay Bartholdi, Robin Demesmaeker, Salif Komi, Charlotte Moerman, Bita Vaseghi, Berkeley Scott, Ryan Rosentreter, Claudia Kathe, Jimmy Ravier, Laura McCracken, and Aaron A. Phillips Nature, vol. 590, no. 7845, 2021, pp. 308–14. 

    Long-term monitoring of intracranial pressure in freely-moving rats; impact of different physiological states Sajedeh Eftekhari, Connar Stanley James Westgate, Katrine Printz Johansen, Signe Rath Bruun & Rigmor H. Jensen Fluids and Barriers of the CNS, 17 (39), 2020. 

    Angiotensin II-induced hypertension in rats is only transiently accompanied by lower renal oxygenation Tonja. W. Emans, Daniela Patinha, Jaap. A. Joles, Maarten. P. Koeners, Ben. J. Janssen & C. T. Paul Krediet Scientific Reports, 8 (1), pp. 16342, 2018, ISBN: 2045-2322. 

  • A rat model of complete atrioventricular block recapitulates clinical indices of bradycardia and provides a platform to test disease-modifying therapies Nam Kyun Kim, David Wolfson, Natasha Fernandez, Minji Shin & Hee Cheol Cho Scientific Reports, 9 , pp. 6930, 2019. 

    Dual implantation of a radio-telemeter and vascular access port allows repeated hemodynamic and pharmacological measures in conscious lean and obese rats C T Bussey, A E de Leeuw, R F Cook, Z Ashley, J Schofield, R R Lamberts Laboratory animals, 48 (3), pp. 250-260, 2014, ISBN: 1758-1117. 

    Recording of intracranial pressure in conscious rats via telemetry Sarah-Jane Guild, Fiona D. McBryde, and Simon C. Malpas Journal of Applied Physiology, 119 (5), pp. 576-581, 2015. 

  • A brainstem monosynaptic excitatory pathway that drives locomotor activities and sympathetic cardiovascular responses Koba, Satoshi; Kumada, Nao; Narai, Emi; Kataoka, Naoya; Nakamura, Kazuhiro; Watanabe, Tatsuo In: Nature Communications, vol. 13, no. 1, 2022.

  • Dr Fiona McBryde

    "The solid state aspect means that the pressure signal is transduced at the very tip...transducing it here that means we're recording exactly what's happening so it's the most high resolution signal that you can currently get"

    Dr Fiona McBryde, University of Auckland

  • Dr Sajedeh Eftekhari

    We showed that it is possible to perform long-term and continuous ICP monitoring in freely moving rats for up to 50 days using this telemetry device. This had a very high degree of stability and the animals are recovering well.

    Dr Sajedeh Eftekhari, Danish Headache Center

 

Go Beyond the Standard Approach with LabChart

 

With LabChart analysis software, your research questions drive the analysis options, not the other way around. Providing the perfect balance of ease, flexibility and power, LabChart allows you to acquire signals from multiple sources simultaneously and apply advanced calculations as your experiment unfolds.

  • Getting started with LabChart is straight-forward and user-friendly meaning the learning curve for new users is much lower.
  • You can choose to either use a range standard analysis tools like cyclic measurements, spectrum, channel calculations, data pad; or you can easily customize macros specific to your own unique research requirements to provide flexibility in your study design.
  • LabChart tracks every action you take while never modifying your raw data, ensuring the integrity of your results so you can focus on the true insights of your research.
  • Flexibility via PowerLab to add other analog signals such as gas analysis, spirometry, stimulation and cystometry into your research with confidence.

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