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Lt

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in the lab and at home

Step by step student lab protocols

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Curriculum based modules

 
Lt LabStation

Course access in lab setting only

Step by step student
lab protocols

Basic concepts & analysis focus

Curriculum based modules

 
LabChart
LabChart

Authentic lab-based data
recording experience

Advanced experimental protocols

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PV Loop and Spike Sorting

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Content

Pharmacology with Lt

This collection explores pharmacological phenomena such as agonists, antagonists, and dose-response relationships using a variety of different tissue preparations.

Click on a lesson name for a synopsis and equipment list or scroll down to see all hardware,
including pre-made systems and kits for your subject area.

+Airways Resistance

Students use a guinea pig trachea dissection to simulate asthma, and measure the effects of histamine and acetylcholine on airway contraction. Students also observe the effects of drugs used to treat asthma, such as salbutamol and theophylline, and their interaction.

This lesson requires one of the PowerLabs below

Products required for this lesson

+Chick Biventer Cervicis

In this lab students use the isolated biventer cervicis muscle from a chick to investigate how the curare poison affects muscle contraction, and which drugs may work as an antidote to curare.

This lesson requires one of the PowerLabs below

+Mammalian Atria

In this lab students use a guinea pig atria to examine how certain drugs affect the frequency and strength of myocardial contraction.

This lesson requires one of the PowerLabs below

+Mammalian Diaphragm

In this lab students use an isolated phrenic-innervated diaphragm muscle preparation to investigate how the drugs suxamethonium, tubocurarine, and edrophonium affect neuromuscular transmission.

This lesson requires one of the PowerLabs below

+Mammalian Heart

In this lab students use an isolated rabbit heart to investigate the effects of selected neurotransmitters and drugs on heart rate and the force of contraction.

This lesson requires one of the PowerLabs below

+Mammalian Jejunum

In this lab students will apply repetitive electrical stimulation to the sympathetic nerves of the isolated rabbit jejunum. This electrical stimulation inhibits rhythmic output from the enteric nerve plexuses, which in turn leads to relaxation of the intestine and reduced gastrointestinal motility. They will also investigate how the drug guanethidine prevents the release of norepinephrine from sympathetic ("adrenergic") nerve terminals.

This lesson requires one of the PowerLabs below

+Mammalian Uterus

In this lab students examine the effects of a variety of drugs (oxytocine, epinephrine, high potassium solution, salbutamol, and propanolol) on a stimulated mammalian uterus preparation.

This lesson requires one of the PowerLabs below

Products required for this lesson

+Stimulated Ileum

In this lab students will use a stimulated guinea pig ileum preparation to investigate how codeine and other drugs affect gastrointestinal motility.

This lesson requires one of the PowerLabs below

+Stimulated Rat Vas Deferens

In this lab students use a stimulated rat vas deferens to study drugs that act presynaptically and test the effects of these drugs on synaptic transmission. They also investigate the effects of a range of adrenoceptor agonists and antagonists.

This lesson requires one of the PowerLabs below

+Toad Rectus Abdominis

In this lab students use an isolated toad rectus abdominis muscle to investigate the effects of tubocurarine and suxamethonium on muscle contraction stimulated by acetylcholine application.

This lesson requires one of the PowerLabs below

Products required for this lesson

+Unstimulated Ileum

In this lab students examine the effects of a variety of drugs on the unstimulated guinea pig ileum preparation. Students also examine the effects of two mystery drugs and determine their mechanism of action.

This lesson requires one of the PowerLabs below

Products required for this lesson

+Unstimulated Rat Vas Deferens

In this lab students use an isolated rat vas deferens to investigate the effects of alpha adrenergic receptor agonists and antagonists, and drugs that affect the amount of norepinephrine in the synaptic cleft.

This lesson requires one of the PowerLabs below

Products required for this lesson

+Vascular Resistance

In this lab students perfuse the isolated hindquarters of a rat at a constant flow. From the changes in pressure required to maintain this flow, the vascular resistance is recorded.

This lesson requires one of the PowerLabs below

+Vascular Smooth Muscle

In this lab students will use arterial rings from a pig coronary artery to explore some drug effects. Arterial rings can be used to demonstrate classical responses to autonomic drugs on vascular smooth muscle. Arterial rings can also be used to show the recently-discovered role of the endothelium in modulating vascular responses.

This lesson requires one of the PowerLabs below

Products required for this lesson

Software Platform

Lt is a cloud-based learning platform that bridges the gap between theory and practice.

Content

Over 340 fully editable nursing, medicine and physiology lessons.

Software

Create, customize and deliver your own interactive content that students can access anywhere.

Hardware

Students can record and analyze physiological signals in Lt using PowerLab, to reinforce theory through experimentation.

Equipment

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Disclaimer: The above lessons, software platform and equipment are not a final recommendation.
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