Radnoti

Radnoti is now an ADInstruments brand.

A merger of expertise, technology, and purpose.

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Radnoti Products

The unique combination of crystal clear Radnoti glassware, modular and robust instruments, and state of the art data acquisition and analysis with PowerLab and LabChart creates a system unsurpassed in quality, finish, and user experience. Providing you more efficient and effective tools for your research laboratory.

Complete Systems and Kits

PowerLab C Rodent Langendorff Foundation System

PowerLab C Rodent Langendorff Foundation System

The PowerLab C Rodent Langendorff Foundation System is designed to perfuse an isolated mouse or rat heart, either in constant perfusion pressure or constant perfusion flow. Included is the high-quality, modular, yet compact ADInstruments Rodent Langendorff Apparatus, which provides flexibility for configuring various isolated heart experimental solutions. Additionally, the system is also supplied with LabChart Lightning software, flexible PowerLab C data acquisition, and hardware for measuring perfusion pressure and temperature. Further tailored parameters can be made by additionally purchasing from a range of compatible isolated heart kits, which includes measurements of left ventricular developed pressure, heart rate and biopotentials.

Isolated Working Heart Systems

Working Heart Systems

Isolated Working Heart Systems provide all the glassware for perfusing small animal hearts, and the acquisition hardware and software for working heart data collection and analysis, including pressure, biopotentials and temperature.

Langendorff Systems - Radnoti (Constant Pressure or Flow)

Langendorff Systems - Radnoti (Constant Pressure or Flow)

Langendorff Foundation Systems that provide high quality glassware to perfuse an isolated mouse or rat heart in Langendorff mode with a versatile PowerLab and LabChart data acquisition and analysis system. Langendorff Isolated Heart Systems can be tailored to measure a number of parameters including pressure, biopotentials and temperature via a wide range of kits, available separately. 

Radnoti Organ Bath Systems - 4 Chamber

Radnoti Organ Bath Systems

The Radnoti Organ Bath Kits combine modular PowerLab data acquisition system options, a Bridge Amplifier, Isometric Transducers and LabChart software with a Radnoti Tissue-Organ Bath Apparatus.

Isolated Perfused Rodent Liver Foundation System

Isolated Perfused Rodent Liver Foundation System

A foundation system that provides the glassware for perfusing an isolated rodent liver to maintain its hepatic function. The system is equipped with acquisition hardware and software for data collection and analysis of parameters including pressure, flow, and temperature.

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Isolated Heart Pressure Kits

Isolated Heart Pressure Kits are hardware add-ons for Langendorff and Working Heart Foundation Systems. Each kit allows the measurement of pressure for a specific application.

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Isolated Heart Action Potential Kits

Isolated heart kits that allow surface cardiac action potential ("ECG") measurements from an isolated perfused rodent heart in Langendorff and Working Heart systems.

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Isolated Perfusion Temperature & pH Kit

A perfusion kit that is designed to measure pH and temperature in any appropriate and meaningful location of an isolated perfusion circuit such as the Langendorff and Working Heart systems.

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Isolated Heart Pacing Kits

The Isolated Heart Pacing Kit is an add-on that allows surface pacing/stimulating of an isolated rodent heart in the Langendorff and Working Heart foundation systems.

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Working Heart Pressure Volume Kits

Using one of state-of-the-art technology to simultaneously measure beat to beat left ventricular pressure and volume of isolated working rodent hearts via an apical stab method.

Instruments

ADInstruments Rodent Langendorff Apparatus

ADInstruments Rodent Langendorff Apparatus

The ADInstruments Rodent Langendorff Apparatus is relatively compact yet modular, which provides flexibility when configuring various isolated heart experimental solutions. This high-quality stainless steel and borosilicate glass apparatus includes an ADInstruments Direct Perfusion Core, which allows recirculation and reoxygenation of perfusate after priming of the apparatus, and measurements to be made close to the cannulated heart.

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Radnoti Working Heart Apparatus

For preparations of working heart, constant flow and constant pressure Langendorff preparations.

Radnoti Langendorff Constant Perfusion Pressure Apparatuses

Radnoti Langendorff Constant Perfusion Pressure Apparatuses

Designed to maintain cardiac function of isolated heart preparations in gravity-fed constant perfusion pressure Langendorff mode, and are available in recirculating and non-recirculating configurations. Several sizes are also available to accommodate different heart sizes including mouse, rat, guinea pig, rabbit or cat.

Radnoti Langendorff Constant Perfusion Flow Apparatuses

Radnoti Langendorff Constant Perfusion Flow Apparatuses

Designed to maintain cardiac function of isolated heart preparations in constant perfusion flow Langendorff mode, and are available in recirculating and non-recirculating configurations. Several sizes are also available to accommodate different heart sizes including mouse, rat, guinea pig, rabbit or cat.

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Radnoti Organ Baths

High quality modular tissue/organ baths, suitable for in vitro dose-response studies in research and teaching labs. 

Radnoti Isolated Rodent Liver/Kidney Apparatus

Radnoti Isolated Rodent Liver/Kidney Apparatus

A glass apparatus designed to maintain the function of an isolated rodent (mouse or rat) liver or kidney preparation, and measure up to two perfusion pressures in the perfusion circuit.

Radnoti Masterflex Peristaltic Pumps

Radnoti Masterflex Peristaltic Pumps

The Masterflex® peristaltic pumps are specifically selected for their dependable and precise performance. Their design centers around a pump drive, the corresponding pump head and tubing.
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Radnoti Thermal Bath/Circulator

This digital, heated circulator allows temperature control from ambient temperature to 120°C. Ideal for the bench top.

RADSTIM series

Radnoti RADSTIM Multi Channel Stimulator

The Radnoti RADSTIM Multi Channel Stimulator series provides extreme flexibility in functionality, both voltage and current stimulation, and a wide stimulation range. In combination with Automation Control System software, they offer significant stimulation power in a compact bundle.

Glassware Components

Radnoti Water Jacketed Reservoir

Radnoti Water Jacketed Reservoirs

Radnoti water jacketed reservoirs are designed to work with a compatible thermoregulated water bath recirculator to maintain a volume of buffer solution at precise temperatures prior to delivery to the perfused or superfused sample.
Filling Funnel

Radnoti Reservoir Filling Funnel

A Reservoir Filling Funnel with an in-built breather tube is designed for use with Radnoti Water Jacketed Reservoirs.

Radnoti Oxygenating Bubblers

Radnoti Oxygenating Bubblers

These Oxygenating Bubblers allow the perfusion media to be gassed effectively by maintaining peak gas tension that ensures optimum sample function. They include either a single or dual fluid return inlets, which are ideal for situations, such as a constant flow setup that requires recirculation of buffer solution with minimal loss.
Radnoti Heating Coils

Radnoti Heating Coils

Radnoti Heating Coils are heat exchangers that are designed to pre-warm or reheat solutions, to ensure that they have the desired temperature, before they come into contact with the tissue or organ sample of study, such as in tissue-organ baths or cell chambers.
Water Jacket and Perfusion Manifolds

Radnoti Water Jacket and Perfusion Manifolds

Radnoti glass manifolds that cater to different flow branching requirements in a perfusion circuit and are a great way for managing flow in multiple applications.

Tissue Organ Baths

Radnoti 1660 Series Hi-Tech Tissue Organ Baths

Radnoti 1660 Series Hi-Tech Tissue Organ Baths

Tissue Organ Baths that represent a state of the art bath with innovative features that enhance experimental design and performance. They are incorporated in Radnoti Organ Bath setups as standard, which they attach to Radnoti Lab Stands via Single Ring Clamps and Universal Stand Clamps.
Radnoti 1583 Series Tissue Organ Baths

Radnoti 1583 Series Tissue Organ Baths

The Radnoti 1583 Series Tissue Organ Baths are elegant and simple, yet highly functional designed baths that have become an indispensable tool for studies in pharmacology, physiology, biochemistry and other biological sciences.
Radnoti 1585 Series Tissue Bath with Built In Electrodes

Radnoti 1585 Series Tissue Bath with Built In Electrodes

The Radnoti 1585 Series Tissue Organ Baths are designed to accommodate the requirement of very small bath volumes, which may be due to working with very small tissue samples or the need to lessen the required amount of expensive drugs.
 Radnoti Specialized Tissue Baths

Radnoti Specialized Tissue Baths

A range of high-quality Radnoti Tissue Organ Baths that are specially designed to accommodate specific tissue and study requirements.

Transducers

Radnoti Micro Pressure Sensor

Radnoti Micro Pressure Sensor

The Radnoti Micro Pressure & Amplifier is designed to provide an alternative to the standard fluid-filled dome or flow through pressure transducers.
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Radnoti Isolated Heart Monophasic Action Potential Electrode Sets

Electrode sets designed to be used together with any ADInstruments Bio Amp (purchased separately) for recording monophasic action potentials from isolated perfused rodent hearts in Radnoti Langendorff or Working Heart systems.

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Radnoti Isolated Heart Pacing Electrodes

Pacing electrodes designed for performing surface pacing/stimulation of an isolated perfused rodent hearts in either a Langendorff or Working Heart system.

Radnoti Platinum Stimulating Electrodes

Radnoti Platinum Stimulating Electrodes

A wide range of platinum electrodes are available for use with Radnoti Tissue-Organ Baths to provide electrical stimulation to a tissue sample via a compatible stimulator.
Flexible Balloon Catheters

Flexible Balloon Catheters

Used with latex balloons for measuring left ventricular pressure in the isolated rat heart preparation.

Accessories

Heart Systems

Radnoti Heart Chambers for Rat/Guinea Pig/Rabbit and Mouse

Radnoti Heart Chambers

The Radnoti Hi-Tech Heart Chambers for Rat/Guinea Pig/Rabbit and for Mouse have been designed for researchers using either Langendorff or working heart systems.

Radnoti Rams Head Heart Chamber Lid Assembly Support Bracket

Radnoti "Rams Head" Heart Chamber Lid Assembly Support Bracket

A support bracket that can be attached to a Radnoti Hi-Tech Heart Chamber Lid, which provides additional support for the attachment of the Radnoti Water Jacketed Flex Tubing Assembly, additional protects for the glass cannulas, and allows easier repositioning of the chamber lid.
Radnoti Bubble Trap Compliance Chamber

Radnoti Bubble Trap Compliance Chamber

A bubble trap and compliance chamber that traps any air bubbles in the perfusate flowing in, serves as a dampener or shock absorber for pulsation related to pump mechanics, and is completely water jacketed for accurate temperature control.
Radnoti 24mm Heart Chamber Adapters

Radnoti 24mm Heart Chamber Adapters

A range of 24 mm diameter borosilicate glass adapters that can be used to adapt the perfusion circuit after passing through the Radnoti Hi-Tech Heart Chamber as required.
Radnoti Oxygenating Chambers

Radnoti Oxygenating Chambers

Radnoti Oxygenating Chambers are designed to provide additional reoxygenation of solution in a perfusion circuit, while maintaining the desired temperature.
Radnoti Post Heart Buffer Reservoir

Radnoti Post Heart Buffer Reservoir

A water jacketed buffer reservoir that attaches to a Radnoti Hi-Tech Heart Chamber via a Radnoti Heart Chamber Adapter (24mm Female to Male Port), which allows collection and rewarming of effluent solution prior to recirculation.
Radnoti Water Jacketed Flex Tubing Assemblies

Radnoti Water Jacketed Flex Tubing Assemblies

The Radnoti Water Jacket Tubing Assembly is designed to address the heat loss that occurs during perfusate transfer through tubing, by providing complete water jacketing to the transfer tubing.

Tissue Bath Systems

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Radnoti 4 to 8 Chamber Conversion Kit

Includes all the tubing and connectors required for combining two 4 channel Radnoti systems to make an 8 channel system.

 Radnoti Transducer Positioner

Radnoti Transducer Positioner

The Radnoti Transducer Positioner is designed to steadily hold via a screw and position a force transducer in Radnoti Organ Baths, which helps to provide stable and accurate pre-tensioning.
Radnoti Micrometer Adapter Assembly

Radnoti Micrometer Adapter Assembly

The Radnoti Micrometer Adapter Assembly is designed to work with Radnoti Transducer Positioner to fulfill the need of extremely precise and accurate measurements of tissue muscle length/tension in a Radnoti Tissue Organ Bath.
Radnoti Tissue Hooks and Clips

Radnoti Tissue Hooks and Clips

We offer a range of tissue hooks and tissue clips designed to work with our Radnoti Tissue Bath Systems.
Radnoti Tissue Ring Supports

Radnoti Tissue Ring Supports

Radnoti Tissue Ring Supports that are designed specifically for mounting tissue ring samples such as aortic, intestinal, vascular or tissue ring segments that need to be set up for an isometric contractile force measurement. The design consists of a combination of a lower L-shaped support and an upper triangular-shaped support.

Other Hardware

Radnoti Ring Clamps

Radnoti Ring Clamps

Ring clamps are designed to hold and attach Radnoti glassware to Radnoti Lab Stands depending on the required apparatus configuration.
Radnoti Lab Stands, Support Rods and Stand Clamps

Radnoti Lab Stands, Support Rods and Stand Clamps

Radnoti Lab Stands that are designed for both durability and flexibility and Radnoti Universal Stand Clamps with its unique V slot configuration, cater to a great range of apparatus configurations.
Radnoti Specialized Tubing and Spare Parts

Radnoti Specialized Tubing and Spare Parts

There are a variety of tubings used in Radnoti glass apparatuses for various required functions.
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In-vitro Liver/Kidney Perfusion Chamber

A glass chamber to be used in a Radnoti Isolated Rodent Liver/Kidney Apparatus for housing, cannulating and perfusing an isolated rodent liver/kidney.

Glass Lab Accessories

Radnoti Micro Weighing Funnels

Radnoti Micro Weighing Funnels

The Radnoti Micro Weighing Funnels are indispensable tools in biological and chemical laboratories. This highly functional but simple design combines two tools in one.

Collection of Tissue Grinders

Tissue Grinders

Radnoti tissue grinders are constructed out of borosilicate glass and are designed for dependable performance, efficiency and durability.

Spare Parts

Heart Systems

Radnoti Glass Cannulas

Radnoti Glass Cannulas for Radnoti High Tech Heart Chambers

Borosilicate glass cannulas that are designed for easy insertion into the lid of the Radnoti High Tech Heart Chambers.
Radnoti Stainless Steel Cannulas for Radnoti High Tech Heart Chambers (Mouse)

Radnoti Stainless Steel Cannulas

Stainless steel cannulas that are designed to accommodate the cannulation of an isolated rodent heart (mice and small rats), which consist of a stainless steel needle shaft that is press fit mounted in a removable female luer.
Radnoti 1.0 µm Glass Fiber Filters

Radnoti 1.0 µm Glass Fiber Filters

Filters can be inserted in the pump output line to remove proteins and other precipitates released by the heart during perfusate recirculation, offering a more convenient alternative to systems with permanent filters that require thorough cleaning after each use.
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Left Ventricle Pressure Latex Balloons

Used with a flexible balloon catheter, a Physiological Pressure Transducer and Bridge Amplifier to measure left ventricular developed pressure (LVDP) in isolated perfused rodent hearts.

Tissue Bath Systems

Radnoti 5 Liter Vacuum Flask

Radnoti 5 Liter Vacuum Flask

An sturdy, thick-walled bottle with built in vacuum adapter lid that is designed to be used as a waste aspirator bottle for a Radnoti Tissue Organ Bath.
Radnoti TNV Valves and Oxygen Disperser Tubes

Radnoti Teflon Needle Valves and Oxygen Disperser Tubes

Radnoti Oxygenating Tubes and gassing manifolds incorporate Teflon needle valves (TNV), which provide a more controllable, accurate and dependable gas flow when compared to the awkward tubing clamping method. Additionally, the sintered disc at the end of oxygenating tubes provides an even and uniform gas dispersion.

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