Perivascular Flowprobes
Measure acute and chronic in vivo flow in both small and large animal blood vessels.
Overview
We are pleased to announce that ADInstruments are now the exclusive global distributors* of Transonic System's leading transit-time flow measurement solutions for life science research.
*excl. Korea and Japan
Measure acute and chronic in vivo flow in both small and large animal blood vessels with this complete line of gold standard Perivascular Flowprobes from Transonic.
Transonic’s signature high-resolution ultrasonic transit-time technology can measure volume blood flows of < 1 mL/min in vessels as small as 0.3 mm in diameter as well as flows up to 200 L/min in 36 mm diameter vessels. Ideal for researchers looking to study various physiological conditions which can alter systemic blood flow and distribution, such as heart failure, ageing, exercise, hypertension and circulatory compromise.
Perivascular flowprobes are placed external to the vessel and do not interfere with flow to the target tissues. For use with Perivascular Flow System Options.
Product Configurations
PS and PR Flowprobes
These Flowprobes loosely encircle the vessel and position two transducers opposing a reflective plate to measure volume flow. The PS and PR series are available in a range of sizes, from 0.5 mm – 20 mm diameter. Often known as mouse nanoprobes, miniature PS series Flowprobes can be used to measure mouse-sized blood flows of < 1 ml/min in 0.5, 0.7 or 1.5 mm vessel diameters. A 75 – 95% fit of the vessel in the probe is recommended for accurate measurements.
- PR and PS series probes are available for acute use (specify with prefix "MA") or as a custom, implantable configuration ("MC").
- The choice of cable orientation is available for the PR and PS series only. Choose the cable orientation that best suits the anatomical site:
- Back "B" = perpendicular to the vessel;
- Side "S" = parallel to the vessel;
- Lateral "L" = for thoracotomy or special application.
- Sizes: n = 0.5, 0.7, 1.5, 2, 2.5, 3, 4, 6, 8, 10, 12, 14, 16, 20 mm vessel diameter
- Acute Use: MA- nPSx (where n = size, series = PS, cable orientation = x)
- MA-nPSB (back cable orientation perpendicular to vessel)
- MA-nPSS (side cable orientation parallel to vessel)
- MA-nPSL (lateral cable orientation 0.5, 1.5, 2, 2.5, 3 only)
- Chronic Use: MC- nPSx-__-__-__-__ (specify cable length, reflector style, connector style, and acute/ chronic calibration)
- Sizes: n = 1, 1.5 mm vessel diameter
- Acute Use:
- MA-nPRB (back cable orientation perpendicular to vessel)
- MA-nPRS (side cable orientation parallel to vessel)
- Chronic Use: MC- nPRx-__-__-__-__ (specify cable length, reflector style, connector style, and acute/ chronic calibration)
Microcirculation Flowprobes 0.5 and 0.7mm
V Series flowprobes, also known as Flex series nanoprobes, are designed for acute flow measurements with high resolution at low flows in small blood vessels, which is ideal for mice. The smaller probe is suitable for vessel diameters of 0.25 - 0.5 mm (mouse and rat femoral or hepatic arteries), while the larger probe is suitable for vessel diameters of 0.35 - 0.7 mm (mouse carotid and mesenteric arteries or portal vein; and rat carotid, superior mesenteric and renal arteries). Each flowprobe has a 60 cm cable and a Flexi-handle with CRA10 connector.
COnfidence Flowprobes
These cardiac output (CO) Flowprobes represent a completely new concept in Flowprobe design. Validated X-pattern full flow illumination is enhanced by a soft plastic probe liner to cushion the vessel, permitting sustained ultrasonic transmission with little need for acoustic coupling gel during acute intraoperative use and safe for extended implantation without complicated protocols to protect the vessel. Ideal for accurate, immediate, beat-to-beat measurements on the ascending aorta and pulmonary artery in large animal studies.
- Please specify cable length and connector (see Details tab).
- Product code: MCnPAU where n = Size
- Sizes: n = 8, 10, 12, 14, 16, 20, 24, 28, 32, 36 mm vessel diameter
- Disposable Ultrafit Liners are available in two styles:
- acute open style for momentary measurement
- closed full-circle style for extended & chronic application
- Each COnfidence Flowprobe is supplied with 1 acute and 1 closed Disposable Ultrafit liner of the same diameter as the Flowprobe. These liners are recommended for single use only and can be purchased separately (reorder) in packs of 5.
Note: The PAU series replaces the PAX series.
Related
Research Applications
Key Features
- Absolute volume flow data from mice to large animals
- Perivascular Flowprobes designed for use with Flowmeter systems
- Acute use and implantable flowprobes for arteries, veins and ducts
- Multiple configurations to meet experimental needs of many animal models
- Unparalleled accuracy and signature high resolution flow waveforms
Support
Support Articles
Our Support Articles contain answers to common questions, how-tos, solutions, and documentation.
Training and Workshops
Maximize time and resources with our customized training services delivered at your facility, on your equipment, on your terms.
Details and Tech Specs
Technical
Flowprobes specifications include:
n = size
ori = cable orientation
ref = reflector style
len = cable length
con = connector
cal = calibration
| Product Code | Product Name |
|---|---|
| MA-n-PS-ori | Precision S series Flowprobes |
| MC-n-PR-ori-ref-len-con-cal | Custom Precision R series Flowprobes |
| MA-n-VB FLEX | Microcirculation Flex V series Flowprobes |
| MA-n-PAU | COnfidence PAU series Flowprobes |
Sizes
| Flowprobes/Flowsensors | n | Units |
|---|---|---|
| PS | 0.5, 0.7, 1.5, 2, 2.5, 3, 4, 6, 8, 10, 12, 14, 16, 20 | Vessel Diameter (mm) |
| PR | 1, 1.5 | Vessel Diameter (mm) |
| V | 0.5, 0.7 | Vessel Diameter (mm) |
| PAU | 8, 10, 12, 14, 16, 20, 24, 28, 32, 36 | Vessel Diameter (mm) |
| PXL | 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 16, 20 | Tubing Outside Diameter (x1/16 inches) |
| PXN | 25 | Tubing Inside Diameter (mm) |
| Code | Orientation | PS Series | PR Series |
|---|---|---|---|
| B | Back | 0.5 – 20 | 1 – 1.5 |
| S | Side | 0.5 – 20 | 1 – 1.5 |
| L | Lateral | 0.5, 1.5 – 2.5 | N/A |
| *Determined by anatomical approach | |||
Calibration
| Code | Description | PS/ PR | PMP/ V | PAU |
|---|---|---|---|---|
| GA | Acute calibration | all sizes | ||
| GC | Chronic calibration | all sizes | N/A | |
| GAC | Acute/ Chronic calibration | N/A | N/A | all sizes |
| Code | Description | PS Series | PR Series | PAU Series |
|---|---|---|---|---|
| WCxx | Up to 60 cm | Nanoprobes | 1 – 1.5 | |
| WCxxx | Up to 100 cm | 2 - 20* | N/A | |
| WCxxx | Up to 200 cm | N/A | N/A | 8 - 36* |
| *Substitute xx for shorter lengths | ||||
| Code | Description | PS Series | PR Series | MA Standard |
|---|---|---|---|---|
| LS | L with slide cover | 3 - 20 | N/A | 3 - 20 PS |
| JN | J without slide | 0.5 - 16 | 1 - 1.5 | 1.5 PSL |
| JFH | J without slide, with flexi-handle | 2PSB | 1 - 1.5PRB | |
| JS | J with slide cover | 2 - 16 | 1 - 1.5 | 2 - 2.5 PS, 1 - 1.5 PR |
| Code | Description | Acute/Chronic | Animals | ID Key Required | PS/ PR | PAU |
|---|---|---|---|---|---|---|
| CRA10 | 10-pin Redel acute connector | Acute | All | No | all sizes | |
| CRS10 | 10-pin Redel sealed connector with cap | Chronic | Dog and larger | No | all sizes | |
| CS12 | 12-pin titanium connector with cap | Chronic | Dog and larger | No | 1 - 20 | all sizes |
| CB12 | 12-pin titanium skin button with cap | Chronic | Dog and larger | No | 1 - 20 | all sizes |
| CM4B | 4-pin mini connector with cap and straight cable | Chronic | Rat, Rabbit and larger | Yes | all sizes | N/A |
| CM4S | 4-pin mini connector with cap and right angle cable | Chronic | Rat and Rabbit | Yes | all sizes | N/A |
| CA4B | 4-pin micro connector with straight cable | Chronic | Rat and Mouse | Yes | 0.5 - 1.0 | N/A |
| CA4S | 4-pin micro connector with right angle cable | Chronic | Rat and Mouse | Yes | 0.5 - 1.0 | N/A |
