… be measured in situ and why tissue oxygen telemetry could be beneficial to your research... Overview: 1.  Why is tissue oxygen an important measure? 2.  Techniques … imaging techniques offer a large field of view, they all require some level of animal restraint/anesthesia that can limit the types of studies performed.   Newer … that be days, weeks, or months. Given that some forms of dementia, stroke and cardiovascular diseases are associated with alterations in blood flow, the ability to …

… PV Loops are the gold-standard method for assessing cardiac function in animal studies. The technique produces load-independent measurements of heart … and treatment models. It turns out, one of the greatest limits of pressure-volume research is the non-standardized approach to performing and publishing this research. … understanding of cardiac function. Anesthetics All anesthetics cause some level of cardiovascular disruption, so the choice must be made carefully based on the …

… What is isolated organ research - and why should you be doing it? As the name implies, isolated organ … of the experiment protocol as required by the study. In addition, since it is an invasive method, you can directly place sensors or electrodes on the organ … Helping with matters of the (isolated) heart: Simplicity & flexibility for cardiovascular and pharmacology research References Yeh T., Wechsler A.S. (1998) The …

… with high fidelity. Below we have outlined some unique intracranial pressure research applications using Mikro-Tip® catheters , plus some applications that … SPR-751S . This broad approach ensures simultaneous measurement of intracranial, cardiovascular, and intrapleural pressures for a complete overview of the impact of … of the Millar pressure catheter » Solid-state vs. Fluid-filled catheters | Invasive blood pressure telemetry» What are the physical dimension of the Mikro-Tip …

… Millar pressure catheters are primarily designed for measuring highly accurate cardiovascular pressures , these sensors have been used for measuring a range of … IFP, and reduced treatment response. Mice are by far the most commonly used animal model in cancer research, leading to a range of well-established methods for direct and …

… the contractility of heart independent of preload and afterload. In this blog, Cardiovascular Physiologist Adam Goodwill (P.h.D) from Indiana University School of … By inserting a PV catheter into the left or right ventricle of an anesthetized animal, you can measure  all load-dependent data for every cardiac cycle from the … interstitial fluid, airway, and spinal pressures Adam G. Goodwill, PhD Assistant Research Professor, Anatomy Cell Biology & Physiology Indiana University School of …