The oxygen consumption is
the amount of oxygen that is used up by the organism's body over
time.
Therefore the calculation
would be:
VO2 = Chminute volume
* (ChO2 – O2inspired) / 100
whereas Chminute
volume is the channel that calculates the Minute Volume
(Spirometry extension), ChO2 is the channel that records
the O2 concentration in % and O2inspired is the O2
concentration of the inspired air (usually 20,9 %).
To be more precise, the
VO2 is calculated as the difference of inspired and expired Minute
volumes:
VO2 = ViFiO2 – VeFeO2
where Fi is an inspired
fraction, Fe is an expired fraction, and Vi and Ve are the minute
volumes of inspired and expired air.
As a standard practice
only expiration (or inspiration) is measured and the other values
need to be calculated using the Haldane transformation (the sum of
O2, CO2 and N fraction equals 1).
Also, a volume correction
is applied: VO2 is expressed at STPD (Standard Temperature and
Pressure in Dry conditions: 0 °C (273.15 K) and 760 mmHg, zero
humidity) but measurements are at BTPS (Body Temperature (36.6 °C),
Ambient Pressure, saturated with water vapour). All these have to be
taken into account. For a detailed description see LabChart Help |
Metabolic | Metabolic Calculations.
The final formula is:
with
and
This translates in LabChart's Channel Calculation | Arithmetics to (see also
attached file):
Ch6*
(760-(13,955-(0,658425*36.6)+(0,0419*(36.6^2))))/(273+36.6)*(273/760)*
(0,2093*((1-(0,01*Ch1)-(0,01*Ch2))/0,7904)-(0,01*Ch1)))
where Ch6 is the Minute Ventilation, Ch1 is %O2 and Ch2 is %CO2.
The
whole calculation can be smoothed using the smoothsec() function:
smoothsec(
(Ch6*
(760-(13,955-(0,658425*36.6)+(0,0419*(36.6^2))))/(273+36.6)*(273/760)*
(0,2093*((1-(0,01*Ch1)-(0,01*Ch2))/0,7904)-(0,01*Ch1)));15)
VCO2
is calculated using the equation that correspond to that given above
for VO2, but with the obvious substitutions:
smoothsec(
(Ch6*
(760-(13,955-(0,658425*36.6)+(0,0419*(36.6^2))))/(273+36.6)*(273/760)*
(0,0003*((1-(0,01*Ch1)-(0,01*Ch2))/0,7904)+(0,01*Ch2)));15)