How can the cuff membrane on the MLT125 rodent tail cuff be replaced?

Cuff membranes should be checked regularly. Over time, the membranes lose their elasticity and pores appear, leading to pressure losses in the system. When such wear has occurred, they should be replaced. Naturally, the service life of the membranes will depend on how well serviced they are and the number of operations carried out.

Generally, they should be changed when the first signs of loss of flexibility or drying are observed. The membrane must be an original PANLAB component. The use of parts made by other manufacturers is not recommended, as there is a major difference in the elasticity of the rubber between different makes, causing unpredictable cuff response.
Proceed as follows to replace cuffs for rats:
  1. Remove the two cylinder-shaped rings from the cuff ends, as shown in the following figures:
  2. Repeat the operation with the O-rings (black rubber rings) that affix the membrane. Remove the damaged membrane.
  3. Insert the new membrane into the cuff. Make sure that it is not taut to prevent additional strain on the cuff pressure. Spontaneous folds and wrinkles are indicative of good positioning. In other words, an improper positioning would look like next figure.
  4. Fold the edge of one of the two overflowing parts of the membrane, covering the peripheral circumference of the cuff.
  5. Fit the O-ring to the cuff to secure the end of the membrane.
  6. Repeat point 4 with the other end, making sure that the membrane walls are not taut.
  7. Fit the other O-ring and close the ends with the rings.
Proceed as follows to replace cuffs for mice:
  • Follow the points above, but under point 3 the membrane must be taut and well-adjusted.
For further technical assistance with this or any other issue, please contact ADInstruments Technical Support by clicking HERE.