When implanting a telemetry transmitter or other device, it is important to consider any possible irritation. Subcutaneous placement may be suitable for some devices but care must be taken to make a pocket to one side of the incision that is big enough for the device to fit easily. Placement of the device directly under the incision should be avoided. The site of device placement should be chosen so that the skin is not stretched too tight over the device as this may cause irritation to the animal.
Intraperitoneal placement provides a good alternative to subcutaneous placement as it reduces the skin irritation. When implanting transmitters consideration must also be given to suitable placement of the device for charging. In rats, the best placement is within the peritoneal cavity.