High-Impact Research Publications Using ADInstruments

Explore a curated selection of peer-reviewed research that utilizes ADInstruments products, from anatomy to zoology and across the life sciences.

A fully implantable telemetry system for the chronic monitoring of brain tissue oxygen in freely moving rats

2012 · D Russell, E Garry, A Taberner et al. · Journal of neuroscience methods
Area Animal > Telemetry Product Tissue Oxygen Telemeter

The ability to monitor tissue oxygen concentration in a specific region of the brain in a freely moving animal could provide a new paradigm in neuroscience research. We have developed a fully implantable telemetry system for the continuous and chronic recordin…

DOI: 10.1016/j.jneumeth.2011.11.019

Switch to glutamate receptor 2-lacking AMPA receptors increases neuronal excitability in hypothalamus and sympathetic drive in hypertension

2012 · D Li, H Byan, H Pan · The Journal of neuroscience : the official journal of the Society for Neuroscience
Area Animal > Telemetry Application Blood Pressure Product Blood Pressure Product Pressure Telemeter

Glutamatergic synaptic input in the hypothalamic paraventricular nucleus (PVN) plays a critical role in regulating sympathetic outflow in hypertension. GluR2-lacking AMPA receptors (AMPARs) are permeable to Ca(2+), and their currents show unique inward rectifi…

DOI: 10.1523/JNEUROSCI.3222-11.2012

Protein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension

2011 · Z Ye, D Li, L Li et al. · The Journal of neuroscience : the official journal of the Society for Neuroscience
Area Animal > Telemetry Application Blood Pressure Product Blood Pressure

Increased glutamatergic input in the paraventricular nucleus (PVN) is important for high sympathetic outflow in hypertension, but the associated molecular mechanisms remain unclear. Here, we determined the role of protein kinase CK2 (formerly casein kinase II)…

DOI: 10.1523/JNEUROSCI.1147-11.2011

A high bandwidth fully implantable mouse telemetry system for chronic ECG measurement

2011 · D Russell, D McCormick, A Taberner et al. · Conference proceedings : ...Annual International Conference of the IEEE Engineering in Medicine and Biology Society.IEEE Engineering in Medicine and Biology Society.Annual Conference
Area Animal > Telemetry Application ECG Signal ECG

We report on the development of a novel system that enables the wireless transmission of high-bandwidth physiological data from a freely moving mouse. The system employs inductive power transfer (IPT) to continuously power a battery-less transmitter using an a…

DOI: 10.1109/IEMBS.2011.6091889

Spectral analysis of electrocorticographic activity during pharmacological preconditioning and seizure induction by intrahippocampal domoic acid

2010 · P Sawant, D Mountfort, D Kerr · Hippocampus
Area Animal > Telemetry Application ECG Application EEG Signal ECG Signal EEG Product Dual Biopotential Telemeter (ECG, EEG and/or EMG)

Previously we have shown that low-dose domoic acid (DA) preconditioning produces tolerance to the behavioral effects of high-dose DA. In this study, we used electrocorticography (ECoG) to monitor subtle CNS changes during and after preconditioning. Young adult…

DOI: 10.1002/hipo.20698

Frequency response of implantable blood pressure telemetry systems

2010 · D McCormick, D Budgett, M Lim et al. · Clinical and experimental pharmacology & physiology
Area Animal > Telemetry Application Blood Pressure Product Blood Pressure

1. Measurement of blood pressure via telemetry in a variety of animal species has become an indispensable part of cardiovascular physiology, drug development and safety pharmacology. 2. These telemetry systems use fluid-filled catheters, which differ from comm…

DOI: 10.1111/j.1440-1681.2010.05406.x

Cyclic intermittent hypoxia enhances renal sympathetic response to ICV ET-1 in conscious rats

2010 · J Huang, T Xie, Y Wu et al. · Respiratory physiology & neurobiology
Area Animal > Telemetry Application Blood Pressure Product Blood Pressure

To test the hypothesis that central changes in sympathoregulation might contribute to sympathoexcitation after cyclic intermittent hypoxia (CIH) we exposed male Sprague-Dawley rats to CIH or to room air sham (Sham) for 8h/d for 3 weeks. After completion of the…

DOI: 10.1016/j.resp.2010.03.008

Sympathetic response to chemostimulation in conscious rats exposed to chronic intermittent hypoxia

2009 · J Huang, S Lusina, T Xie et al. · Respiratory physiology & neurobiology
Area Animal > Telemetry Application Blood Pressure Product Blood Pressure

Exposure to cyclic intermittent hypoxia (CIH) is associated with elevated arterial pressure and sustained sympathoexcitation, but the causes of the augmented sympathetic activity remain poorly understood. We recorded arterial pressure, heart rate, and renal sy…

DOI: 10.1016/j.resp.2009.02.010

Powering implantable telemetry devices from localized magnetic fields

2007 · D McCormick, A Hu, P Nielsen et al. · Conference proceedings : ...Annual International Conference of the IEEE Engineering in Medicine and Biology Society.IEEE Engineering in Medicine and Biology Society.Annual Conference
Area Animal > Telemetry

This paper presents a novel method of inductively powering an implantable telemetry device over a large area. The system is based around an array of individually tuned series resonant circuits distributed across a charging pad. By varying the frequency of the…

DOI: 10.1109/IEMBS.2007.4352793