How is mitral regurgitation characterized by left ventricle pressure volume loops?

Mitral Regurgitation results when the mitral valve fails to close and blood flows back into the left atrium during systole. There is no true isovolumic contraction since blood flows back into the left atrium. There is also no true isovolumic relaxation since when the aortic valve closes and the heart begins to relax, blood continues to flow back into the left atrium.


Left ventricle pressure volume loops may appear distorted as depicted in the following example: 


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