What does the end diastolic pressure volume relationship (EDPVR) tell me on set of pressure volume loops?

End Diastolic Pressure Volume Relationship (EDPVR) relates to the passive filling curve of the left ventricle during diastole and is a measure of passive chamber stiffness (see attached citations). The slope of EDPVR is the reciprocal of compliance and is used to measure ventricular stiffness. A decrease in compliance may be related to ventricular hypertrophy, and an increase in compliance might be related to a dilated cardiomyopathy.


PV Basics.pdf

Am J Physiol Heart Circ Physiol-2005-Burkhoff-H501-12.pdf

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