In this discussion, three leading experts reveal how they are using the Transonic Tubing System in their in vitro circulatory loop research. This session will explore best practices, challenges and tips and tricks for mock circulatory loop setups. Whether you're an experienced researcher or curious to know more about volume flow measurement in a tubing setup, this session promises to offer valuable insights.
Key Highlights:
- Hear from three researchers who currently use Transonic Tubing Systems and Flowsensors in their research covering mock circulatory loop and cardiovascular applications.
- Discover the unique benefits of the Transonic Tubing System and its pivotal role in advancing circulation research.
User Presentations:
- Dr. Andrew Stephens
In Vitro Evaluation of Oversizing in Surgical Valve Replacement
Dr. Stephens will discuss how he uses Transonic tubing systems in his research into the effects of heart valve oversizing in different sized patients. In his presentation, he will cover how his team used a mock circulatory loop to evaluate different surgical valve sizes and different aortic roots, simulating different levels of valve oversizing.
- Dr. Antony McNamee
Haemocompatibility Evaluation of Cardiovascular Devices: Leveraging Transonic Systems within ASTM F1841 Frameworks
Dr. McNamee will explore how he uses Transonic flowsensors in in vitro haemocompatibility testing of cardiovascular devices. With particular reference to ASTM F1841 guidance for assessing blood damage in mock circulatory loops, he will share his recent experimental setups, where Transonic systems were integrated for precise flow measurement and closed-loop control.
- Sai Paladee
Silicone Hearts and Models: PV Loop Generation and BiVACOR Stress Tests
Sai Paladee will share insights on the development and use of a custom anatomical fluid model designed to evaluate BiVACOR’s performance under diverse physiological conditions, including suction events, variations in vascular resistance, and changes in aortic compliance. He will also highlight the unique biventricular silicone setup of the St Vincent's mock circulatory loop and demonstrate how Transonic flowsensors are being integrated to generate pressure–volume (PV) loops for advanced device assessment.
Panel Discussion:
- Panel discussion and Q&A
- Speakers will address common system, setup and measurement challenges and offer valuable advice for aspiring circulatory and cardiovascular researchers
Related Products:
Transonic Tubing System
Transonic Flowsensors
Perivascular and Tubing Flowmeters
Powerlab C - Instrument Interface
LabChart Pro
LabChart Lightning
Additional Resources:
Transonic Tubing Setup
Guest Speakers:
Dr. Andrew Stephens
Senior Lecturer and Researcher,
School of Electrical Engineering and Robotics
Director, Advanced Cardiorespiratory Engineering Laboratory (ACE LAB)
Queensland University of Technology, Queensland
Dr. Andrew Stephens is a Senior Lecturer and Researcher at Queensland University of Technology, School of Electrical Engineering and Robotics. He is also the director of the Advanced Cardiorespiratory Engineering Laboratory (ACE LAB), which focuses on designing and improving devices to treat heart and lung failure.
Dr. Antony McNamee
Senior Lecturer in Biorheology, School of SHS - Exercise Science
DECRA Fellow of the Australian Research Council
Griffith University, Queensland
Dr. Antony McNamee is a Senior Lecturer in Biorheology at Griffith University and an ARC DECRA Fellow. His research focuses on blood physiology, with a particular emphasis on how life-support systems and artificial organs interact with red blood cells and cardiovascular function. Dr. McNamee has developed a distinctive multidisciplinary skillset across biophysics, cardiovascular physiology, medical device testing, and allied engineering, enabling him to design and apply novel technologies for device evaluation and clinical translation. He has contributed to international standards development and leads research programs on blood rheology, haemocompatibility testing, artificial blood development, microfluidics, and red blood cell biomechanics.
Sai Paladee
Research Assistant, St Vincent's Hospital,
University of New South Wales, Sydney
Sai-Kishan Paladee is a Research Assistant at St Vincent’s Hospital, working under Professor Chris Hayward on mechanical circulatory support devices. He completed a Master of Biomedical Engineering and a Bachelor of Mechatronic Engineering (Hons) at UNSW, with a thesis on adaptive control for the HeartMate 3 LVAD. His current research focuses on evaluating BiVACOR TAH performance using advanced mock circulatory loop testing.