Oxford Optronix has a history of creating sophisticated equipment for clinical medicine and life sciences, with applications in tumor monitoring and angiogenesis, intra-cranial monitoring in brain injury and stroke, and oxygen transport and blood substitutes. While the direct streaming of data into LabChart is new, journal publications show that ADInstruments and Oxford Optronix equipment have actually been used in the same research for a long time - something that will now be much easier! No need to import or export data files into different programs or use another device as an interface, with the Oxford Optronix Device Enabler installed, LabChart will automatically detect your Oxford Optronix tissue vitality monitor, ready to record and analyze data into the same document as other signals recorded with your PowerLab.
It’s fascinating to see the variety of research using both Oxford Optronix devices and ADInstruments hardware and software - and now that we’re directly compatible through LabChart, we look forward to seeing even more. Here are some great examples:
In 2007, Khan et al published a study of the effects of caffeic acid phenethyl ester as a treatment following ischemic stroke. They found that the drug provided neurovascular protection in the animal model through antioxidant, anti-inflammatory and hemodynamic effects, alongside inhibition of factors mediating apoptotic cell death.
More recently, Rafferty et al explored factors that could constrain the evolution of live birth in reptiles by investigating embryonic development in turtles. Their results showed that localized and extreme hypoxia in turtle oviducts halts the development of their embryos until the eggs are laid - a useful trait for an animal that lays it's eggs in batches but also a probable explanation why live birth has never evolved in any species of turtle.
And published last month in the journal Spinal Cord, Budgell et al investigated how transcutaneous electrical nerve stimulation increases spinal cord blood flow following acute, non-destructive compression - with hopes that further research in this field could one day have clinical implications for the treatment of human spinal cord compression.
It's really exciting how the LabChart Compatibility project is gaining momentum, helping us to increase the range of biological parameters that you can detect, display and analyze in one place. (Read more about other devices that work with LabChart here.) Do you have hardware you'd like to see become LabChart Compatible? Contact us here, it would be great to hear from you!
Khan, M., Elango, C., Ansari, M. A., Singh, I. and Singh, A. K. (2007), Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia. Journal of Neurochemistry, 102: 365–377. doi: 10.1111/j.1471-4159.2007.04526.x
Rafferty, A., Evans, R., Scheelings, T. F., and Reina, R. (2013), Limited Oxygen Availability In Utero May Constrain the Evolution of Live Birth in Reptiles. The American Naturalist, Vol. 181, No. 2 (February 2013), pp. 245-253
Budgell, B. S., Sovak, G., and Soave, D. (2014), TENS augments blood flow in somatotopically linked spinal cord segments and mitigates compressive ischemia. Spinal Cord advance online publication 22 July 2014; doi: 10.1038/sc.2014.120