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  3. High-Impact Research Publications Using ADInstruments

High-Impact Research Publications Using ADInstruments

Explore a curated selection of peer-reviewed research that utilizes ADInstruments products, from anatomy to zoology and across the life sciences.

Diversity of cortical activity changes beyond depression during Spreading Depolarizations

2023 · Azat Nasretdinov, Daria Vinokurova, Coline Lemale et al. · Nature Communications
Product PowerLab Product LabChart

Abstract Spreading depolarizations (SDs) are classically thought to be associated with spreading depression of cortical activity. Here, we found that SDs in patients with subarachnoid hemorrhage produce variable, ranging from depression to booming, changes in…

DOI: 10.1038/s41467-023-43509-3

DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters

2023 · Nienke Stege, Tim Eijgenraam, Vivian Teixeira et al. · Circulation Research
Product PowerLab Product LabChart Product Bio Amp

BACKGROUND: The p.Arg14del variant of the PLN (phospholamban) gene causes cardiomyopathy, leading to severe heart failure. Calcium handling defects and perinuclear PLN aggr…

DOI: 10.1161/circresaha.123.323304

Electroacupuncture improves swallowing function in a post-stroke dysphagia mouse model by activating the motor cortex inputs to the nucleus tractus solitarii through the parabrachial nuclei

2023 · Lulu Yao, Qiuping Ye, Yun Liu et al. · Nature Communications
Product LabChart

Abstract As a traditional medical therapy, stimulation at the Lianquan (CV23) acupoint, located at the depression superior to the hyoid bone, has been shown to be beneficial in dysphagia. However, little is known about the neurological mechanism by which this…

DOI: 10.1038/s41467-023-36448-6

Humidity sensors that alert mosquitoes to nearby hosts and egg-laying sites

2023 · Willem Laursen, Gonzalo Budelli, Ruocong Tang et al. · Neuron
Product PowerLab Product LabChart

DOI: 10.1016/j.neuron.2022.12.025

Hybrid assembly of polymeric nanofiber network for robust and electronically conductive hydrogels

2023 · Huimin He, Hao Li, Aoyang Pu et al. · Nature Communications
Product PowerLab

Abstract Electroconductive hydrogels have been applied in implantable bioelectronics, tissue engineering platforms, soft actuators, and other emerging technologies. However, achieving high conductivity and mechanical rob…

DOI: 10.1038/s41467-023-36438-8

Intestinal neuropod cell GUCY2C regulates visceral pain

2023 · Joshua Barton, Annie Londregran, Tyler Alexander et al. · Journal of Clinical Investigation
Product PowerLab Product LabChart

DOI: 10.1172/jci165578

Liquid crystal elastomer based dynamic device for urethral support: Potential treatment for stress urinary incontinence

2023 · Seelay Tasmim, Zuha Yousuf, Farial Rahman et al. · Biomaterials
Product PowerLab Product LabChart Product Bridge Amp

DOI: 10.1016/j.biomaterials.2022.121912

Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension

2023 · Sarasa Isobe, Ramesh Nair, Helen Kang et al. · Nature Communications
Product PowerLab Product LabChart

Abstract Pulmonary arterial hypertension (PAH) is a progressive disease in which pulmonary arterial (PA) endothelial cell (EC) dysfunction is associated with unrepaired DNA damage. BMPR2 is the most common genetic cause of PAH. We report that human PAEC with…

DOI: 10.1038/s41467-023-43039-y

Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling

2023 · Luca Rosalia, Caglar Ozturk, Debkalpa Goswami et al. · Science Robotics
Product PowerLab Product LabChart

Aortic stenosis (AS) affects about 1.5 million people in the United States and is associated with a 5-year survival rate of 20% if untreated. In these patients, aortic valve replacement is performed to restore adequate hemodynamics and alleviate symptoms. The…

DOI: 10.1126/scirobotics.ade2184

Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation

2023 · Jone López-Erauskin, Mariana Bravo-Hernandez, Maximiliano Presa et al. · Nature Neuroscience
Product PowerLab Product Stimulus Isolator

DOI: 10.1038/s41593-023-01496-0

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