Abstract The prevalence of heart failure with preserved ejection fraction (HFpEF) is increasing, while treatment options are inadequate. Hypertension and obesity-related metabolic dysfunction contribute to HFpEF. Nitro-oleic acid (NO2-OA) impacts me…
Abstract Background Very preterm infants often require respiratory support after birth with current recommendations suggesting the use of continuous positive airway pressure (C…
Increased cardiac excitability and reduced electrical coupling promote cardiac arrhythmia and can be quantified by input resistance ( R m ), pacing threshold ( I…
Abstract Preeclampsia (PE) and peripartum sepsis are two complications of pregnancy and are often associated with disturbed renal function due possibly to dysregulated renin angiotensin system. Here we evaluated hemodynamic and renal consequences of…
Hearing loss, affecting individuals of all ages, can impair education, social function, and quality of life. Current treatments, such as hearing aids and implants, aim to mitigate these effects but often fall short in addressing the critical issue of accuratel…
Abstract Small, gaseous molecules such as nitric oxide, carbon monoxide and hydrogen sulfide are produced as signalling molecules in mammalian cells. Here, we show that low concentrations of cyanide are generated endogenously in various mammalian ti…
