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  • Blog (109)
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Pressure-volume catheter placement in the left ventricle - Carotid vs. Apical approach

Blog
… (LV); the carotid (closed-chest) and apical (open-chest) approach. Below, cardiovascular physiologist DeWayne Townsend (DVM, Ph.D.) from the University of … heart for catheterization, which can influence the hemodynamic properties of the cardiovascular system.   Potential to damage the myocardium -   One major challenge …
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ADI people: Introducing Paula Croft, European Support Team Manager

Blog
… Paula Croft, the Manager of our European Support Team. Paula’s background in cardiovascular research at Kings College, London - where she used both the PowerLab … I wanted to work in the pharmaceutical industry but took my first job working in Cardiovascular Research at Kings College London - this is where I was first …
2024-ADI Rodent Langendorff-670x560.png

Choosing the right perfusate for your isolated Langendorff heart preparation

Blog
… >> So what are some of the perfusate systems you can use? Dr. Melanie White , cardiovascular researcher and pathology lecturer at the University of Sydney shares … isolated heart studies Our isolated heart systems - Simplicity and flexibility for cardiovascular and pharmacology research Three benefits of isolated organ research …
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The Benefits of Using Telemetry in Research

Blog
… Telemetry » Solid-state sensors at the catheter tip - why settle for less? » Cardiovascular Applications with Kaha Sciences Telemeters » Five unique neuroscience …
Image

Powerful equations: mathematics meets biology at the Science Museum, London

Blog
… people’s lives’, it’s hard to imagine a better fit than recent work by cardiovascular pharmacologist Dr Manasi Nandi and mathematician Dr Philip Aston , who … in intensive care units (ICU) around the world. Mathematician Dr Philip Aston and cardiovascular pharmacologist Dr Manasi Nandi will co-present an exhibit at the … Sciences and Medicine at King’s College London, Manasi’s research is focused on cardiovascular dysfunction in sepsis - a huge problem in hospitals which occurs when …
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Connecting with clinicians: Tips for translating your research to clinical practice

Blog
… in the first place? To help answer this question, we spoke to Fiona McBryde , a Cardiovascular Physiologist from the University of Auckland whose preclinical …
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Getting to the heart of the problem: Understanding the causes of cardiac hypertrophy

Blog
… mediating hypertrophic growth. Dr. Min Zi , a Researcher in the Division of Cardiovascular Sciences at Manchester University (UK), is one such scientist who is … Countries. Circulation 134(6), 441-450 (2016). 2. Mathew, J. et al . Reduction of cardiovascular risk by regression of electrocardiographic markers of left ventricular …
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The Lt Veterinary Physiology Collection: Access 60 online lessons designed for your animal science course!

Blog
… physiology lessons online to teach across key body systems, including nervous, cardiovascular, reproductive, endocrine, and more. Developed in association with … 3 Musculoskeletal System 4 Nervous System 5 Somatic and Special Senses 6 Cardiovascular System 7 Lymphatic and Immune Systems 8 Respiratory System 9 Digestive …
woman running with text next to her reading 'how the heart keeps up'

Research Insight | Professor Satoshi Koba: How the heart keeps up

Blog
… Monosynaptic Excitatory Pathway That Drives Locomotor Activities and Sympathetic Cardiovascular Responses.” Nature Communications , vol. 13, no. 1, Aug. 2022, … his team inhibited the circuit during freely-occurring exercise. As expected, the cardiovascular support for the exercising animals dropped, reverting to … as complicated as stopping the motivation to exercise, it simply switched the rats cardiovascular activity back to its typical, non-exercising patterns. The rats could …
Four people walking toward a plane

2025 PowerLab C Competition Winner: Jeremy Cohen

Blog
… A recent addition to Jeremy’s research program is the impact of altered gravity on cardiovascular regulation and hemodynamic responses. Under the guidance of Dr Richard … Jeremy has been working with the European Space Agency and Novespace, taking these cardiovascular measures during parabolic flights. This has enabled Jeremy and his team to assess the impact  of hypergravity and microgravity on the cardiovascular system. This research can help us to understand cardiovascular …
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Best practices for setting-up an isolated Langendorff heart preparation

Blog
… The isolated Langendorff heart has been a cornerstone of cardiovascular research for more than a century. Its long-standing scientific …
pressure volume loop labchart

PV Tips and Tricks: Expert advice for measuring pressure-volume loops in mice

Blog
… happening in the first place!   In this blog,  DeWayne Townsend (DVM, Ph.D.), a cardiovascular physiologist from the University of Minnesota Medical School, provides …
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Introduction to PV loops: Understanding points on the PV loop and measures of cardiac function

Blog
… the contractility of heart independent of preload and afterload. In this blog, Cardiovascular Physiologist Adam Goodwill (P.h.D) from Indiana University School of …
High Impact Publication Series

Neonatal Hyperoxia, Circadian Signals, and Spontaneous Hypertension - Five High Impact Publications From July 2024

Blog
… in July 2024.   Neonatal Hyperoxia Exposure Leads to Developmental Programming of Cardiovascular and Renal Disease in Adult Rats. In this article, published in … investigate the long-term effects of neonatal exposure to high oxygen levels on cardiovascular and renal health in rats. Using ADInstruments data acquisition … suggest that early-life exposure to high oxygen levels can cause lasting damage to cardiovascular and renal systems, highlighting the importance of developing targeted …
2024-Chris West Heart Spine PV Loop

Associate Professor Chris West: The heart, the spine, and the PV loop

Blog
… the injury have to try to function with incomplete information. Life-threatening cardiovascular complications are a common side effect. While his interest in … Rugby Squad for 5 years during his Master’s and PhD, assessing their autonomic and cardiovascular performance on every scale he could, measuring the impact of partial … fatigue or ventilatory constraint during or following exercise. However, their cardiovascular function was significantly impacted by their injuries, resulting in a …
High Impact Publication Series

Tumor Vasculature and Cardiac Fibrosis - High-Impact Publications from September 2024

Blog
… on Myocardial Stiffness Assessed by Natural Wave Imaging. Published in JACC. Cardiovascular Imaging Image Example ECG data in LabChart In this article, Venet et … exaggerated reflex. These findings are significant in understanding the heightened cardiovascular risks during exercise in heart failure patients. Read more: … Physiological Pressure Transducers EEG   Role of the Peripheral Chemoreceptors in Cardiovascular and Metabolic Control in Type 2 Diabetes. Published in The Journal of …
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ADInstruments workshops tour China

Blog
… courses. They were very impressed by these revoluti onary teaching solutions. The Cardiovascular workshop at  Wenzhou Medical University, in Wenzhou , with around 80 people attending. Dr Tan demonstrated several important applications in cardiovascular research, including pressure-volume (PV) studies , wire myography , …
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12 lead ECG placement for researchers - a simple guide to ECG positions

Blog
How to correctly place ECG leads to perform a 12 lead ECG on a human subject, for cardiovascular, physiological, and pharmacological research.
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Watch webinar: An introduction to isolated Langendorff heart - Experimental considerations and best practices

Blog
… Dr. Melanie White, cardiovascular researcher from the University of Sydney, provides a practical and … from a rat model)   The isolated Langendorff heart has been a cornerstone of cardiovascular research for more than a century. Its long-standing scientific …
Image

Celebrating Women in Science: Two Free Illustrations to Download and Keep!

Blog
… producing groundbreaking research in their respective fields...   Manasi Nandi - Cardiovascular Pharmacologist Dr. Manasi Nandi Ph.D. is a cardiovascular pharmacologist and a Senior Lecturer in Integrative Pharmacology at … College London.  Manasi’s research interest is in sepsis and septic shock, and the cardiovascular dysregulation that occurs in those patients. Her interdisciplinary …

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