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Four Cardiovascular Applications Using Kaha Sciences Telemetry

Kaha Sciences telemetry solutions combine wireless power and state of the art pressure sensor technology to provide unrivaled accuracy and long-term recording in cardiovascular research.

With options to measure pressure (arterial, venous, and ventricular), ECG, sympathetic nerve activity, and tissue oxygen concentrations, 24/7 over the course of your experiment - Kaha Sciences' telemeters allow you to measure a range of cardiovascular signals to meet your research needs.

Related: Benefits of using telemetry in research »

Kaha Sciences Telemetry – Cardiovascular applications:

Pressure

Kaha Sciences rat pressure telemeters use the Millar Mikro-Tip® solid-state sensor technology, at the catheter tip to allow high fidelity, accurate, and repeatable pressure recordings. The 2 Fr (0.66 mm) sensor can record a range of pressures including; arterial blood pressure, venous pressure, and ventricular pressure.

Pressure Telemetry

Related: Benefits of using solid-state pressure sensors »

Telemeters are available with single (TRM54P) or dual (TRM54PP) catheters in lengths of 9, 15 or 25cm so customers can tailor their experiment and record up to two pressures with one telemeter.

The quality and accuracy of the signal allows confidence in basic feature extraction across animals (e.g. systolic, diastolic) but also facilitates more complex analysis such as spectral analysis and cardiac output from BP and dP/dt calculations from LVP.

Read more: Tips and Tricks for Successful Rat Telemetry Blood Pressure Recordings »

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ECG

Biopotential telemeters (TR50B and TR50BB) allow the long-term recording of ECGEMG, or EEG in freely moving rats. Our wireless power technology supports long-term, continuous recording at high sampling rates (2kHz) which is ideal for monitoring spontaneous pathophysiological activity, such as ectopic beats or the generation of arrhythmia.

ECG Telemetry

The TRM54PB telemeter also allows customers to combine ECG and pressure measurements from the same animal to assess cardiac and cardiovascular function.

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Sympathetic Nerve Activity (SNA)

The TRM56SP telemeters allow users to simultaneously record concurrent blood pressure and SNA from the same animal. This is particularly useful in studies of the development of hypertension and cardiovascular control.

Sympathetic Nerve Activity Telemetry

The input range of the SNA leads is ±60µV making it ideal for activity recording from fine, peripheral autonomic nerves.

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Tissue Oxygen

The TR57Y tissue oxygen telemeter is the only device available on the market that can measure tissue oxygen concentration from conscious rats, in real-time.

Tissue Oxygen

The telemeter uses a stable carbon paste electrode and can measure local ischemia and tissue metabolic activity in the kidney and brain. Combined with our wireless power technology researchers have been able to assess circadian variability in kidney tissue oxygen thanks to the ability to record 24/7.

Related: Tissue oxygen telemetry - How does it work and why is it beneficial to your research? »

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For more information about Kaha Sciences telemeters, or to discuss your specific research application please contact your nearest ADInstruments support representative.


Related resources:

Tips and tricks for long-term recordings of left ventricular pressure in rats »

Tips for handling and analyzing large telemetry data sets »

Five neuroscience applications using Kaha Sciences Telemetry »

Kaha telemeters: Surgical Videos and Webinars  »

19 May 2021

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