Mouse Pressure Volume (PV) Catheters from Millar

Overview

Millar Pressure-Volume (PV) catheters have revolutionized cardiovascular research in small animals. These ultra-miniature catheters are capable of measuring left ventricular pressure and volume simultaneously and continuously from the intact, beating hearts of mice. Built to the highest quality standards, the catheters combine a proven Mikro-Tip® pressure sensor with four electrodes to collect real-time pressure-volume data, enabling minimally invasive, continuous, intracardiac PV analysis.

Each contains four platinum electrodes arranged in two pairs. The paired electrodes are separated by 0.5 mm, while the distance between the pair varies between catheters. The pressure sensor is located in the center, between the two pairs of electrodes.

They can be used with:

MPVS Ultra Foundation Systems
MPVS Ultra Single Segment Pressure-Volume Unit
MPVS-400 Pressure-Volume Unit (replaced by MPVS Ultra Single Segment Pressure-Volume Unit)

MPVS PV-Units require the MPVS Ultra Cable Pack (purchased separately).

Calibration: A Pressure Gauge kit that provides the necessary items to calibrate the pressure transducers is available. The PV Loop Add-On for LabChart provides step-by-step Workflows to guide you through the calibration process.

Millar Mikro-Tip Catheters require a certain level of care to ensure accuracy and the anticipated lifespan of your catheters. Tergazyme (Alconox, Inc.) is required for cleaning and ensuring the removal of proteinaceous soils, tissue, blood and body fluids from the catheter. Please refer to Alconox, Inc.’s website to purchase from your local supplier. For a few best practice tips to help get you started with your catheters, see our guide here. Additionally, the purchase of an ESD Adjustable Wrist Strap w/ 10’ Coil Cord (Blue, 4mm Snap) is highly recommended to protect these catheters from electrostatic discharge (ESD) damage during handling.

Non-repairable discount options are available for the Mouse PV Catheter (SPR-839 only). Contact us to find out more and if this is the right option for you.

Configurations

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Apical)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-SPR-848

SPR-848

This PV catheter is ideally suited for use in mice hearts using the open-chest, ventricular apical stab method. This catheter has two pressure sensors.

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Carotid)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-SPR-864

SPR-864

This PV catheter is ideally suited for use in mice hearts using the closed-chest, carotid method. The catheter has two pressure sensors.

Mouse PV Catheter (1.4F, 4E, 4 mm, Taper)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-SPR-853

SPR-853

This is an ultra-miniature PV Catheter (1.4F Polyimide Nylon) with a tapered end, suitable for use in mice.

Mouse PV Catheter (1.4F, 4E, 4.5 mm, 3.5 cm, PI)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-SPR-839

SPR-839

This is a repairable PV catheter with an effective length of 3.5 cm, suitable for use in mice. An economical, non-repairable model is also available.

Mouse PV Catheter (1.4F, 6E, Selectable Seg, 4 mm/6 mm)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-SPR-866

SPR-866

This is a selectable, segmented PV Catheter, containing 2 pressure sensors, which can be used in measuring ventricular function in a mouse. It is suitable for use with the MPVS Ultra PV Unit (large and small animals), which has replaced the MPVS-400.

Please note, however, that this catheter cannot be used with the MPVS Ultra Single Segment PV Unit.

Mouse PV Catheter (1F, 4E, 3.0 mm, 4.5 cm, PI, Non Repairable)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-PVR-1030

PVR-1030

This PV catheter's length (3.25 cm) and electrode spacing (3.0 mm) are optimal for ventricular volume measurement in smaller mice, and for right ventricle measurements. Coupled with the smaller diameter (1F), this is the world’s smallest pressure-volume catheter!

For standard-sized animals, the the Mouse PV Catheter (1F, 4E, 4.5 mm, 4.5 cm, PI, Non Repairable) is recommended.

Mouse PV Catheter (1F, 4E, 3.5 mm, 4.5 cm, PI, Non Repairable)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-PVR-1035

PVR-1035

This PV catheter's length (3.25 cm) and electrode spacing (3.5 mm) are optimized for ventricular volume measurement in smaller mice (< 25 g), and for right ventricle measurements. The smaller diameter (1F) of the catheter minimizes obstruction of blood flow in the vessel and allows improved surgical access to the right ventricle and pulmonary arteries.

For standard-sized animals, the Mouse PV Catheter (1F, 4E, 4.5 mm, 4.5 cm, PI, Non Repairable) is recommended.

Mouse PV Catheter (1F, 4E, 4.5 mm, 4.5 cm, PI, Non Repairable)
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https://www.adinstruments.com/products/mouse-pv-catheters#product-PVR-1045

PVR-1045

This PV catheter's length (3.25 cm) and electrode spacing (4.5 mm) are optimized for ventricular volume measurement in standard-sized mice (25 g or greater). The 1F diameter of the catheter material minimizes the obstruction of blood flow in the vessel and allows for improved surgical access, which enables the use of smaller, younger mice for earlier detection of disease or treatment.

Features

Ultra-miniature 1-1.4 F catheters, each housing a pressure sensor.
Pressure and volume measurement from a single instrument.
Flexible, durable catheter material (Polyimide Nylon).
No motion artifact or damping of pressure signal.
Pressure measurement at the source.
High frequency response.

Applications: These catheters combine pressure sensors and electrodes for simultaneous, high-fidelity pressure and volume measurements, enabling minimally invasive, continuous, intracardiac PV analysis.

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Details and Tech Specs

Product Codes

SPR-848

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Apical)

SPR-864

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Carotid)

SPR-853

Mouse PV Catheter (1.4F, 4E, 4 mm, Taper)

SPR-839

Mouse PV Catheter (1.4F, 4E, 4.5 mm, 3.5 cm, PI)

SPR-866

Mouse PV Catheter (1.4F, 6E, Selectable Seg, 4 mm/6 mm)

PVR-1030

Mouse PV Catheter (1F, 4E, 3.0 mm, 4.5 cm, PI, Non Repairable)

PVR-1035

Mouse PV Catheter (1F, 4E, 3.5 mm, 4.5 cm, PI, Non Repairable)

PVR-1045

Mouse PV Catheter (1F, 4E, 4.5 mm, 4.5 cm, PI, Non Repairable)

Technical

Mouse Pressure-Volume Catheters

Model number	Length (cm)	Tip (French)	No. sensors	Electrode spacing	Use-life	Repairable
PVR-1030	3.25	1	1	3 mm	Reusable - Non-Sterile	no
PVR-1035	3.25	1	1	3.5 mm	Reusable - Non-Sterile	no
PVR-1045	3.25	1	1	4.5 mm	Reusable - Non-Sterile	no
SPR-839	3.25	1.4	1	4.5 mm	Reusable - Non-Sterile	yes
SPR-848		1.4	2	4.5 mm	Reusable - Non-Sterile
SPR-853		1.4	1	4.0 mm	Reusable - Non-Sterile
SPR-864	3.5	1.4	2	4.5 mm	Reusable - Non-Sterile	yes
SPR-866		1.4	2	4 mm/ 6 mm	Reusable - Non-Sterile

Mouse PV Catheter (1.4F, 4E, 4 mm, Taper)

Mouse PV Catheter (1.4F, 4E, 4.5 mm, 3.5 cm, PI)

Mouse PV Catheter (1.4F, 6E, Selectable Seg, 4 mm/6 mm)

Mouse PV Catheter (1F, 4E, 3.0 mm, 4.5 cm, PI, Non Repairable)

Mouse PV Catheter (1F, 4E, 3.5 mm, 4.5 cm, PI, Non Repairable)

Mouse PV Catheter (1F, 4E, 4.5 mm, 4.5 cm, PI, Non Repairable)

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Apical)

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Carotid)

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Apical)

Mouse PV Catheter (1.4F, 2P, 4E, 4.5 mm, Carotid)

Mouse PV Catheter (1.4F, 4E, 4 mm, Taper)

Mouse PV Catheter (1.4F, 4E, 4.5 mm, 3.5 cm, PI)

Mouse PV Catheter (1.4F, 6E, Selectable Seg, 4 mm/6 mm)

Mouse PV Catheter (1F, 4E, 3.0 mm, 4.5 cm, PI, Non Repairable)

Mouse PV Catheter (1F, 4E, 3.5 mm, 4.5 cm, PI, Non Repairable)

Mouse PV Catheter (1F, 4E, 4.5 mm, 4.5 cm, PI, Non Repairable)

Mouse PV Catheters