Mouse PV Catheters
Overview
Millar offers the world's only solid-state Pressure-Volume (PV) catheters for cardiovascular research in mice.
These ultra-miniature catheters combine both pressure sensors and electrodes for simultaneous measurement of left or right ventricular pressure and volume measurements continuously from the intact, beating hearts of mice.
Built to the highest quality standards, Millar PV catheters provide end-diastolic, and end-systolic volumes, allowing researchers to calculate stroke volume, ejection fraction, cardiac output, stroke work, Tau, dP/dt Max and Min, contraction time, and relaxation time.
Each catheter combines a proven Mikro-Tip MEMs pressure sensor with four electrodes to collect real-time pressure-volume data, enabling minimally invasive, continuous, intracardiac PV analysis.
There are two versions of each catheter size available:
- Those compatible with the Millar MPVS Duo Pressure-Volume System*
- Those compatible with the traditional MPVS Ultra Pressure-Volume Systems (these systems are no longer sold, but supporting catheters are still available)
*These catheters are also compatible with ADV550 / ADV500 units previously sold by Transonic Scisense.
Non-repairable discount options are available for the Mouse PV Catheter (SPR-839 and SPR-839A only). Contact us to find out more and if this is the right option for you.
Required Products:
- MPVS Duo Foundation System, or
- MPVS Duo + PowerLab and LabChart (or other DAQ of choice)
Recommended:
- Volume Calibration Cuvettes to convert volume units into mL for mice and rats may be purchased separately, if required but not included in your Configuration (see below).
Product Configurations
Mouse PV Catheter (1.1F, 4E, 3.0mm, 4.5cm, PI, Non Repairable)
This PV catheter's length (3.5 cm), diameter (1.1F), and electrode spacing (3.0 mm) are optimal for ventricular volume measurement in smaller mice, and for right ventricle measurements.
For standard-sized animals, the Mouse PV Catheter (1.1F, 4E, 4.5 mm, 3.5 cm, PI, Non Repairable) is recommended.
Compatible with Millar MPVS Ultra Units.
Mouse PV Catheter (1.1F, 4E, 3.5mm, 4.5cm, PI, Non Repairable)
This PV catheter's length (3.5 cm) and electrode spacing (3.5 mm) are optimized for ventricular volume measurement in smaller mice (< 25 g), and for right ventricle measurements. The smaller diameter (1.1F) of the catheter minimizes obstruction of blood flow in the vessel and allows improved surgical access to the right ventricle and pulmonary arteries.
For standard-sized animals, the Mouse PV Catheter (1.1F, 4E, 4.5 mm, 3.5 cm, PI, Non Repairable) is recommended.
Compatible with Millar MPVS Ultra Units.
Mouse PV Catheter (1.1F, 4E, 4.5mm, 4.5cm, PI, Non Repairable)
This PV catheter's length (3.5 cm) and electrode spacing (4.5 mm) are optimized for ventricular volume measurement in standard-sized mice (25 g or greater). The 1.1F diameter of the catheter material minimizes the obstruction of blood flow in the vessel and allows for improved surgical access, which enables the use of smaller, younger mice for earlier detection of disease or treatment.
Compatible with Millar MPVS Ultra Units.
Mouse PV Catheter (1.4F, 4E, 4.5mm, 3.5cm, PI)
This Polyimide Mikro-Tip pressure-volume catheter for normal/large mice has a 3.5 cm effective length with a pressure sensor (1.4F) and four electrodes (electrode spacing 4.5 mm). The pressure sensor is centered between E2 & E3. Catheter body is 0.8F. Compatible with Millar MPVS Ultra Units. The SPR-839 is reusable and can be repaired.
Mouse PV Catheter (1.1F, 4E, 3.0mm, 3.5cm, PI, Non Repairable, Duo)
This PV catheter's length (3.5 cm), diameter (1.1F), and electrode spacing (3.0 mm) are optimal for ventricular volume measurement in smaller mice, and for right ventricle measurements.
For standard-sized animals, the Mouse PV Catheter (1.1F, 4E, 4.5 mm, 3.5 cm, PI, Non Repairable) is recommended.
Compatible with Millar MPVS Duo Units and ADV500/550 units previously sold by Transonic Scisense.
Mouse PV Catheter (1.1F, 4E, 3.5mm, 4.5cm, PI, Non Repairable, Admittance/Conductance)
This PV catheter's length (3.5 cm) and electrode spacing (3.5 mm) are optimized for ventricular volume measurement in smaller mice (< 25 g), and for right ventricle measurements. The smaller diameter (1.1F) of the catheter minimizes obstruction of blood flow in the vessel and allows improved surgical access to the right ventricle and pulmonary arteries.
For standard-sized animals, the Mouse PV Catheter (1.1F, 4E, 4.5 mm, 3.5 cm, PI, Non Repairable) is recommended.
Compatible with Millar MPVS Duo Units and ADV500/550 units previously sold by Transonic Scisense.
Mouse PV Catheter (1.1F, 4E, 4.5mm, 4.5cm, PI, Non Repairable, Duo)
This PV catheter's length (3.5 cm) and electrode spacing (4.5 mm) are optimized for ventricular volume measurement in standard-sized mice (25 g or greater). The 1.1F diameter of the catheter material minimizes the obstruction of blood flow in the vessel and allows for improved surgical access, which enables the use of smaller, younger mice for earlier detection of disease or treatment.
Compatible with Millar MPVS Duo Units and ADV500/550 units previously sold by Transonic Scisense.
Mouse PV Catheter (1.4F, 4E, 4.5mm, 3.5cm, PI, Duo)
This Polyimide Mikro-Tip pressure-volume catheter for normal/large mice has a 3.5 cm effective length with a pressure sensor (1.4F) and four electrodes (electrode spacing 4.5 mm). The pressure sensor is centered between E2 & E3. Catheter body is 0.8F. Compatible with Millar MPVS Duo Units and ADV500/550 units previously sold by Transonic Scisense. The SPR-839 is reusable and can be repaired.
Related
Products
Research Applications
Cardiovascular Hemodynamics
Working Heart
Cardiovascular Isolated Heart Systems
In Vitro Pharmacology + Isolated Tissue and Organs
Key Features
- Ultra-miniature 1.1-1.4 F catheters, each housing a pressure sensor.
- Pressure and volume measurement from a single instrument.
- Flexible, durable catheter material (Polyimide Nylon).
- No motion artifact or damping of pressure signal.
- Pressure measurement at the source.
- High frequency response.
Applications:
These catheters combine pressure sensors and electrodes for simultaneous, high-fidelity pressure and volume measurements, enabling minimally invasive, continuous, intracardiac PV analysis.
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Details and Tech Specs
Technical
Best Practice Care:
Millar Mikro-Tip Catheters require a certain level of care to ensure accuracy and the anticipated lifespan of your catheters.
- Tergazyme (Alconox, Inc.) is required for cleaning and ensuring the removal of proteinaceous soils, tissue, blood and body fluids from the catheter. Please refer to Alconox, Inc.’s website to purchase from your local supplier.
- For MPVS Ultra Compatible Catheters - purchase of an ESD Adjustable Wrist Strap w/ 10’ Coil Cord (Blue, 4mm Snap) is highly recommended to protect these catheters from electrostatic discharge (ESD) damage during handling. These straps are not required for MPVS Duo compatible catheters.
- For a few best practice tips to help get you started with your catheters, see our guide here.
Calibration:
- MPVS Duo compatible catheters: The MPVS Duo provides step-by-step workflows to guide you through the calibration process.
- MPVS Ultra compatible catheters: The PV Loop Add-On for LabChart provides step-by-step Workflows to guide you through the calibration process.
| Model number | Length (cm) | Tip (French) | No. sensors | Electrode spacing | Use-life | Repairable | Compatibility |
|---|---|---|---|---|---|---|---|
| PVR-1030 | 24 | 1.1 | 1 | 3 mm | Reusable - Non-Sterile | no | MPVS Ultra |
| PVR-1030A | 24 | 1.1 | 1 | 3 mm | Reusable - Non-Sterile | no | MPVS Duo ADV500 ADV550 |
| PVR-1035 | 24 | 1.1 | 1 | 3.5 mm | Reusable - Non-Sterile | no | MPVS Ultra |
| PVR-1035A | 24 | 1.1 | 1 | 3.5 mm | Reusable - Non-Sterile | no | MPVS Duo ADV500 ADV550 |
| PVR-1045 | 24 | 1.1 | 1 | 4.5 mm | Reusable - Non-Sterile | no | MPVS Ultra |
| PVR-1045A | 24 | 1.1 | 1 | 4.5 mm | Reusable - Non-Sterile | no | MPVS Duo ADV500 ADV550 |
| SPR-839 | 4.5 | 1.4 | 1 | 4.5 mm | Reusable - Non-Sterile | yes | MPVS Ultra |
| SPR-839A | 4.5 | 1.4 | 1 | 4.5 mm | Reusable - Non-Sterile | yes | MPVS Duo ADV500 ADV550 |
