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  • Blog (27)
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Image

Ventricular Pressure Volume + PV Loops

Research Application
… on safety standards. Surgical Instruction Video Series: Pressure Volume (PV) and Invasive Pressure ADInstruments has been working alongside surgical expert …
Image

Introduction to PV loops: Understanding points on the PV loop and measures of cardiac function

Blog
… Pressure-volume (PV) loops are the gold standard for measuring direct, real-time cardiac function. By … simultaneously plotting real-time ventricular pressure against ventricular volume, PV loops provide a unique, quantitative approach for determining the contractility of … University School of Medicine, provides a comprehensive introduction to the PV loop, how it compares to other techniques, and tips for interpreting measures of …
pressure volume loop labchart

PV Tips and Tricks: Expert advice for measuring pressure-volume loops in mice

Blog
… Variability in your pressure-volume (PV) measurements can be introduced at any stage of the experiment, from your catheter … your experimental design, plus handy tips and tricks for collecting high-quality PV loop data. Overview Fluid management   - Blood loss and insensible fluid loss …
Four catheters and the title 'Should you be using admittance or conductance calibration for PV Loops?'

Should you be using Admittance or Conductance calibration for PV Loops?

Blog
… Pressure-volume (PV) loops are the gold standard for measuring direct, real-time cardiac function. By … simultaneously plotting real-time ventricular pressure against ventricular volume, PV loops provide a unique, quantitative approach for determining the contractility of … measurement forms the basis for the volume measurement.  Image A pressure-volume loop graphs pressure against volume within the ventricle to produce a …
2024-Chris West Heart Spine PV Loop

Associate Professor Chris West: The heart, the spine, and the PV loop

Blog
… performance from the load on the heart. This is the reason Chris and his team use PV loops. Related: Introduction to PV loops: Understanding points on the PV loop and measures of cardiac function “With typical cardiac measures you have to ask …
Image

Keeping Cardiovascular Researchers in the Loop: Why studying pressure-volume loops could be useful for you...

Blog
… researcher? Find out why you should consider studying ventricular pressure-volume (PV) loops - the gold standard for measuring direct, real-time cardiac function. Why study PV Loops? Pressure-volume loops are the gold standard for measuring direct, real-time … severity, prognosis and response to therapies in patients with PH.   Analyzing PV Loop data - The problem with right ventricular PV loops Analyzing PV loop data is …
Image

Watch webinar: Cardiac Pressure-Volume Loop Data Analysis - Tips & Tricks

Blog
… In this free on-demand webinar, PV loop experts DeWayne Townsend (DVM, Ph.D.) and Adam Goodwill, (Ph.D.) discuss how to collect and analyze high-quality pressure-volume loop data. …
Image

Understanding the Importance of PV Catheter Calibration in Admittance and Conductance Systems

Blog
… Transcript Pressure-Volume (PV) Loops are the gold standard for measuring direct, real-time cardiac function. There are two technologies available for doing PV loop studies, admittance and conductance. Both systems call for calibration …
Image

Pressure-volume catheter placement in the left ventricle - Carotid vs. Apical approach

Blog
… Ventricular pressure-volume (PV) relationships are a well established and comprehensive means for assessing … miniaturization of catheters and optimization of surgical procedures, ventricular PV analysis has successfully been translated to small rodents, opening up the … is the best surgical approach for your PV research. For more information about PV loop data acquisition and analysis, check out Dr. DeWayne Townsend and Dr. Adam …
A blue tile with the words 'Standardizing Pressure-Volume research for more reliable outcomes', an image of a pv loop, and a photo of dr oliver wearing

Standardizing Pressure-Volume research for more reliable outcomes

Blog
… PV Loops are the gold-standard method for assessing cardiac function in animal … has an influence on the interpretation of the end Image Points on the PV Loop. results, limiting the potential impact of each experiment, complicating our …
Image

Getting to the heart of the problem: Understanding the causes of cardiac hypertrophy

Blog
… drug targets and therapies for treating the disease 3,4,5 .  The power of the PV Loop - A visual representation of disease progression  Min regularly uses  ventricular pressure-volume (PV) analyses to characterize and study cardiac hypertrophy. PV Loops are generated by …
Image

New Release: LabChart 8.1.11

Blog
… correction due to invalid volume data  to even the rarest of cases, with ease. PV Loop 2.4.1 Release We've optimized the PV Loop echo volume calibration so that it accurately calculates ESV and EDV values …
MPVS Duo blog tile

The Best of Both Worlds - The MPVS Duo from Millar

Blog
… The MPVS Duo is an intuitive pressure-volume loop measurement system from Millar.  Designed to work in conjunction with Millar’s gold-standard Mikro-Tip PV Duo catheters for the perfect combination of ease and accuracy, so you can carry … you interpret more transparent. One System for All Animal Models Millar Mikro-Tip PV Duo catheters range from 1F to 5F, enabling pressure-volume measurements to be …
catheter positioning blog tile

The Importance of Catheter Positioning in Pressure-Volume Data Collection

Blog
… Pressure-volume (PV) loop studies are the gold-standard for measuring direct cardiac function, providing … researchers can utilize XY View in Labchart to confirm the shape of their PV loop and aid in catheter placement. The challenges noted above can translate into …
Aascha D'Elia

High output, high performance: Dr Aascha D'Elia

Blog
… something new to work on, and you never get bored.” Image Aascha and her team run PV Loop experiments to assess cardiac function. They're highly specialized experiments … the experiments efficiently is crucial. Image LabChart’s latest version of the PV Loop Analysis Module includes new features designed to give you precise and …
Laurencie Brunel

Dr Laurencie Brunel: Understanding the impact of mitral valve replacement

Blog
… the load-independent contractility of the left ventricle by plotting continuous PV loops through LabChart, giving them a clear view of the impact each intervention had on left ventricular function.  Related: Introduction to PV loops: Understanding points on the PV loop and measures of cardiac function “I think we are showing that altering even the …
Blog Image for Millar acquisition of Transonic Scisense

Support for Scisense Customers

Blog
… to access optimal solutions for pressure measurements and pressure-volume (PV) loops. Transonic has also entrusted ADInstruments, as Millar’s exclusive global … will continue to have access to cutting-edge pressure and pressure-volume (PV) catheters and systems to meet industry needs.   “We’re pleased to partner with … together to produce and distribute gold-standard pressure and pressure-volume (PV) catheter technology to the global market. Learn more about ADInstruments and …
Image

Schooling up at Plato BioPharma

Blog
… surgery using Millar catheters , and shoring up their understanding of PV theory, heart mechanics and recorded parameters. Plato BioPharma is a … team, being able to perform this surgery and seeing the real-time visualization of PV loops during catheter insertion, traction and adjustment has given them a whole …
Image

Broken heart? Cardiac regeneration 'Therepi' might just be your savior

Blog
… cells and (5) Therepi with cells and refills. Using ventricular pressure-volume (PV) loop analysis to measure changes in cardiac function To measure the efficacy of the … they performed functional haemodynamic measurements using an echo ultrasound and a PV catheter ( Millar Mikro-Tip ) for each of the test groups. Ventricular pressure …
Image

Troubleshooting your Millar Catheter: Three common problems and how to fix them

Blog
… hardware e.g. your  Bridge Amp , PowerLab , C Series Interface or MPVS Duo PV Unit ? Contact your nearest ADInstruments technical support specialist today - … in the left ventricle – Carotid vs. Apical approach Expert tips for measuring PV loops in mice Understanding Ventricular Pressure-Volume Catheter Calibrations and Experimental Design PV Loop Module - For left and right ventricular PV Loop analysis Invasive Blood Pressure …

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