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Respiratory Pressure

Respiratory Pressure

Pressure is an important function supporting respiration. A pressure gradient is required to generate respiration flow. In spontaneous respiration, inspiratory flow is achieved by creating a sub-atmospheric pressure in the alveoli by increasing the volume of the thoracic cavity under the action of the inspiratory muscles. During expiration, the intra-alveolar pressure becomes slightly higher than atmospheric pressure and gas flow to the mouth results. 

Airway pressure in humans can recorded through the use of pressure transducers inserted into the throat and connected to our fully isolated and human approved blood pressure amplifiers, a PowerLab data acquisition unit and LabChart analysis software. 

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Respiratory Pressure

Products and Solutions

Record multiple<br />
signals at one time

Record multiple
signals at one time

Integrate base products with your own choice of transducer

Integrate base products with your own choice of transducer

Mix and match products<br />
for a custom solution

Mix and match products
for a custom solution

Integrate with<br />
other physiological<br />
recording options

Integrate with
other physiological
recording options

In conjunction with our complete system shown below, any device (i.e. ergometer, exercise bike, treadmill) with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of event in LabChart. So you have even more flexibility and can integrate all your data streams in one place.

All of our hardware recommended for human use is backed by the appropriate safety certification standards. More information on safety standards.

Typical Respiratory Pressure Studies

Hypoxia studies

Respiratory disease studies e.g. COPD, asthma, emphysema, cystic fibrosis

Allergen/inflammation studies

Restrictive or Constrictive airway disorders

Signals Supported

dP/dT
+

dP/dt is a signal derived from pressure, typically ventricular blood pressure, that indicates the change in pressure over time.

Pressure
+

Record and analysis a range of respiratory and  pulmonary pressures including

  • Airway resistance (pressure difference developed per unit flow into or out of the lungs)
  • Airway conductance (flow generated per unit of pressure drop across the airways)
  • Compliance (volume change per unit of pressure change)
  • As well as Maximal Inspiratory Pressure (MIP) (greatest subatmospheric pressure developed during inspiration against an occluded airway)
  • And Maximal Expiratory Pressure (MEP) (highest pressure that can be developed during a forceful expiratory effort against an occluded airway) 

Flexible Data Acquisition

ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart analysis software and a PowerLab data acquisition unit you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

LabChart

Enabling Discovery

LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.

LabChart and Respiratory Pressure

PowerLab

LabChart

Data with Integrity

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.

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All your Respiratory Pressure analysis in one place

LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.

Sampling from two regions in the airway

Millar Mikro-Tip catheters with dual pressure sensors allow users to simultaneously sample from two regions in the airway, allowing for simple comparison of the differentiation in airway pressure, as well as resistance and compliance. This is a very useful approach when studying airway restriction.

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Features and Add-Ons

Additional acquisition and analysis features and add-ons to support your Respiratory Pressure studies:

Explore Respiratory Pressure Data in LabChart Reader

LabChart Reader is a free application for conducting limited analyses of LabChart data. Download a trial package with example data below.

Platform Required

Thanks! Your trial package is now downloading.

Once downloaded, please unzip the folder and install the LabChart Reader application.

Open the "LabChart Data Files" folder to find data files (".adicht"). Data files can be opened in LabChart Reader by double clicking on the file name.

Request a demo

Thank you for your interest in Respiratory Pressure. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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Ask a question

Thank you for your interest in Respiratory Pressure. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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