By interrogating the gas exchange occurring in the lungs during breathing we can learn a lot about respiratory processes.
The exchange of gases (O2 & CO2) between the alveoli and blood occurs by simple diffusion: O2 diffusing from the alveoli into the blood and CO2 from the blood into the alveoli. Diffusion requires a concentration gradient. So, the concentration (or pressure) of O2 in the alveoli must be kept at a higher level that in the blood & the concentration (or pressure) of CO2 in the alveoli must be kept at a lower level than in the blood. We do this by breathing - continuously bringing fresh air (with a high percentage of O2 and much smaller fraction of CO2) into the lungs and alveoli.
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In conjunction with our complete system shown below, any device (i.e. ergometer, exercise bike, treadmill) with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of event in LabChart. So you have even more flexibility and can integrate all your data streams in one place.
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Hypoxia studies
Respiratory disease studies e.g. COPD, asthma, emphysema, cystic fibrosis
Allergen/inflammation studies
Sports Research
The simultaneous measurement of respiratory gas concentrations and airflow with our metabolic systems permits the calculation of the following metabolic parameters.
Temperature is a useful tool in determining many factors such as subject health or the stability of an experimental preparation. It is also usefulas a calculation factor for comparing measurements taken in different states.
ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart analysis software and a PowerLab data acquisition unit you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.
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LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.
Data with Integrity
High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.
LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.
Respiratory Gas Analysis using the Exercise Physiology System and the Metabolic Add-On for LabChart.
RER is calculated by dividing VCO2 by VO2, therefore if the VCO2 is higher than expected but the VO2 is normal, this would explain the high RER. Alternatively, if the VCO2 is normal, but the VO2 seems low, this would also explain the high RER. In either case, the raw CO2 and O2 values should be assessed by recording known concentrations of each to make sure these are calibrated correctly. If the CO2 and O2 values are not contributing to the high RER, the flow calibration should be checked. Other factors that might cause a high RER are subject panting/breathing uncomfortable once the face mask is attached creating a higher than normal CO2 output. Another common problem can be air leaks, either from around the face mask which must be completely air tight, or within the breathing circuit.
×Additional acquisition and analysis features and add-ons to support your Respiratory Gas Analysis studies:
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This video demonstrates how to use the Gas Analyzer to measure respiratory gas concentrations...
Thank you for your interest in Respiratory Gas Analysis. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
×Thank you for your interest in Respiratory Gas Analysis. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
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