Respiratory Gas Analysis
By interrogating the gas exchange occurring in the lungs during breathing we can learn a lot about respiratory processes.
The exchange of gases (O2 & CO2) between the alveoli and blood occurs by simple diffusion: O2 diffusing from the alveoli into the blood and CO2 from the blood into the alveoli. Diffusion requires a concentration gradient. So, the concentration (or pressure) of O2 in the alveoli must be kept at a higher level that in the blood & the concentration (or pressure) of CO2 in the alveoli must be kept at a lower level than in the blood. We do this by breathing - continuously bringing fresh air (with a high percentage of O2 and much smaller fraction of CO2) into the lungs and alveoli.
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Integrate with other physiological recording options
In conjunction with our complete system shown below, any device (i.e. ergometer, exercise bike, treadmill) with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of event in LabChart. So you have even more flexibility and can integrate all your data streams in one place.
All of our hardware recommended for human use is backed by the appropriate safety certification standards. More information on safety standards.
Complete Systems or Kits
An exercise physiology equipment kit suitable for conducting respiratory gas analysis and metabolic measurements in student laboratories investigating the effects of exercise.
Suitable for performing respiratory experiments on human subjects. Capable of recording inhalation and exhalation parameters such as minute ventilation and tidal volume, as well as PIF, PEF, FVC and FEV1.
Measure & analyze the physiological effects of exercise. A complete physiology recording system for monitoring cardiorespiratory and metabolic function during exercise.
Related Components and Products
Data acquisition and analysis re-imagined. Make unique discoveries with unlimited freedom and flexibility.
Engineered for precise, consistent, reliable data acquisition of a wide range of physiological signals. PowerLab gives you the reproducible data you need while meeting the strictest international standards.
Creates a platform allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots.
The Spirometer is a precision differential pressure transducer for measurements of respiration flow rates. ADInstruments provides spirometry accessories for a range of respiratory experiments.
The Spirometer Pod is ideal for teaching, which provides entry level human respiratory flow measurements using an appropriate respiratory flow head and PowerLab data acquisition system.
The Gas Analyzer allows the continuous measurement of respiratory gas concentrations from rats through to humans. It houses an infrared carbon dioxide sensor and optical oxygen detector. The CO2/O2 respiratory gas analyzer samples expired gas from a mixing chamber with a damped, micro-vacuum sampling pump. A flow control knob on the front of the unit provides sampling rates of 35 to 200 ml/min, although maximum flow values may vary for different sizes and lengths of tubing.
Included with the Gas Analyzer:
Nasal Temperature Probes are ideal for measuring nasal air temperature as an indicator of respiration. Designed to operate over the range 0 - 50°C, they are well suited to applications such as biomedical temperature monitoring requiring repeatability, high sensitivity and rapid response. May be connected to the Thermistor Pod or with an 8-pin DIN connector for use with any Bridge Amp. Units with extra lead length of 10 m are also available.
The SpO2 Ear and Finger Clips are designed to measure oxygen saturation. They are approved for human use and supplied with the appropriate Oximeter Pod.
The Thermistor Temperature Sensor is ideal for measuring air temperature from a gas mixing chamber. The thermistor is secured in a T-connector using a Tuohy Borst adapter and can be attached to a luer port. The can be attached to the the Gas Mixing Chamber and Gas Analyzer for CO2 and O2 analysis in metabolic studies. The thermistor has a lead length of 0.9 meter and is designed to operate over the range 0 - 50°C with a high sensitivity and rapid response.
Contains items related to spirometry and gas analysis for use with the Exercise Physiology System.
A 180 cm (6 ft) long smooth bore tubing with integral end fittings (35 mm ID) for connection to the Gas Mixing Chamber and Face Mask.
Provides an easy and reliable method of calibrating respiratory equipment.
Other Hans Rudolph Syringes are available on request with volumes ranging from 10 mL to 7 L.
Clean bore tubing, 25 cm in length with an inner diameter of 35 mm, connects Disposable Filters to the Respiratory Flow Heads and Heated Pneumotach.
Contains desiccant material (silica gel) for removing water from a gas stream. It can be used multiple times and recharged by replacing the desiccant material. The silica gel changes color from blue to pink when it needs replacing.
Size (L x B x H): 9.5 x 6 x 2.5 cm
Desiccant volume: ~70.5 g 4Å Molecular Sieve with indicator
Used with the One-Way Valve Mouthpiece to prevent any air leakage when used in conjunction with the Douglas Bags.
Kits include silicon face mask, head strap and Y-shaped two-way non-rebreathing valve. Range of sizes available. Silicon faces masks can also be purchased separately
An adapter used to connect the Clean Bore Tubing to Respiratory Flow Heads and Heated Pneumotach.
For use with the gas analyzer. Has a 4.7L capacity for collecting, mixing and sampling expired respiratory gases.
Used to minimize effects of condensation on the flow head in spirometry studies.
Connects the Douglas bag to the Gas Analyzer with the Modified Tubing Adapter.
For respiratory flow circuit studies in a non-rebreathing, 2-way configuration. It has very low resistance, minimal leakage and miniscule dead space due to the unique tricuspid valve diaphragm that collapses onto itself and allows nearly straight-through flow.
Can also be purchased as part of the Exercise Breathing Kit.
Included in the Exercise Consumables Kit and designed for connection of the gas analyzer to the Douglas bag.
300L or 1000L flow heads suitable for use on adults in resting and exercising conditions. Supplied with tubing for connection to the spirometer or spirometer pod.
Vinyl mouthpiece (10pk) for use with disposable filters in respiratory studies.
The Tubing Adapter is an autoclavable blue thermoplastic rubber that is 50 mm long. Both ends have an inside diameter of 35 mm (1 3/8") and it is used to connect the Respiratory Flow Head 1000L to the Gas Mixing Chamber outlet port.
A molecular sieve desiccant for refilling the Desiccant Cartridge (1 kg ).
The desiccant material contains silica gel which changes color from blue to pink when the material needs to be replaced.
Pack of 50 disposable droplet filters. These bacterial-viral filters have 99.999% bacterial filtration efficiency and 99.99% viral filtration efficiency, while also offering low flow resistance and low dead space of 45 mL. Used in human respiratory experiments to remove water droplets from the air stream and protect against cross-contamination.
Dimensions: Subject end 31 mm outer diameter, tubing end 34 mm outer diameter.
A pack of 60 Douglas Bags (120 liters), designed to hold expired air for respiratory studies.
Can also be purchased as part of the Exercise Breathing Consumables Kit.
Dimensions: The opening has an outside diameter of 37-39 mm (including top ridge) and an inside diameter of 30 mm.
The In-line Filter connects directly to the sampling port of the Gas Analyzer to protect the transducers from moisture and damaging particulates.
This is a pack of 50 disposable nose clips used to clamp the nostrils comfortably while making respiratory measurements. Each nose clip features soft, grooved pads to give it a gentle, non-slip grip to ensure a proper fit, and is held comfortably in place by spring action. Made of white plastic.
Disposable, one-way valve mouthpieces with a length of 65 mm and outer diameter of 30 mm. They are made from white cardboard and are supplied in a pack of 100.
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Flexible Data Acquisition
ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart or LabChart Lightning analysis software and a PowerLab data acquisition unit, you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.
LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.
Data acquisition and analysis re-imagined. Make unique discoveries with unlimited freedom and flexibility.
High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.
A modular data acquisition foundation system that provides unparalleled flexibility for researchers looking to invest in customizable, reliable solutions for both now, and in the future.
All your analysis in one place
LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.
Features and Add-Ons
Additional acquisition and analysis options to support your Respiratory Gas Analysis analysis:
Data acquisition and analysis re-imagined.
Make unique discoveries with unlimited freedom and flexibility.
