By interrogating the gas exchange occurring in the lungs during breathing we can learn a lot about respiratory processes.
The exchange of gases (O2 & CO2) between the alveoli and blood occurs by simple diffusion: O2 diffusing from the alveoli into the blood and CO2 from the blood into the alveoli. Diffusion requires a concentration gradient. So, the concentration (or pressure) of O2 in the alveoli must be kept at a higher level that in the blood & the concentration (or pressure) of CO2 in the alveoli must be kept at a lower level than in the blood. We do this by breathing - continuously bringing fresh air (with a high percentage of O2 and much smaller fraction of CO2) into the lungs and alveoli.
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Integrate with other physiological recording options
In conjunction with our complete system shown below, any device (i.e. ergometer, exercise bike, treadmill) with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of event in LabChart. So you have even more flexibility and can integrate all your data streams in one place.
All of our hardware recommended for human use is backed by the appropriate safety certification standards. More information on safety standards.
A complete physiology recording system for monitoring cardiorespiratory and metabolic function during exercise.
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The Spirometer is a precision differential pressure transducer for measurements of respiration flow rates. ADInstruments provides spirometry machines, kits, and parts for a range of respiratory...
The Spirometer Pod measures respiratory flow rates in humans in conjunction with an appropriate respiratory flow head and PowerLab.
The Gas Analyzer allows the continuous measurement of respiratory gas concentrations from rats through to humans. It houses an infrared carbon dioxide sensor and optical oxygen detector....
The Thermistor Temperature Sensor is ideal for measuring air temperature from a gas mixing chamber. The thermistor is secured in a T-connector using a Tuohy Borst adapter and can be attached to a...
Nasal Temperature Probes are ideal for measuring nasal air temperature as an indicator of respiration.
Heated Pneumotach 800 L with Heater Controller
Used to minimize effects of condensation on the flow head in spirometry studies.
Exercise Physiology Accessory Kit
Contains items related to spirometry and gas analysis for use with the Exercise Physiology System.
Suitable for performing respiratory experiments on human subjects. Capable of recording inhalation and exhalation parameters such as minute ventilation and tidal volume, as well as PIF, PEF, FVC...
300L or 1000L flow heads suitable for use on adults in resting and exercising conditions. Supplied with tubing for connection to the spirometer or spirometer pod.
One-Way Valve Mouthpiece (pack of 100)
Disposable, one-way valve mouthpieces with a length of 65 mm and outer diameter of 30 mm. They are made from white cardboard and are supplied in a pack of 100.
Interface Tubing (Douglas Bag to Gas Analyzer)
Connects the Douglas bag to the Gas Analyzer with the Modified Tubing Adapter.
For respiratory flow circuit studies in a non-rebreathing, 2-way configuration.
Tubing Adapter (35mm inner diameter)
The Tubing Adapter is an autoclavable blue thermoplastic rubber that is 50 mm long.
Clean-bore Tubing & Tubing Adapter
Clean bore tubing, 25 cm in length with an inner diameter of 35 mm, connects Disposable Filters to the Respiratory Flow Heads and Heated Pneumotach.
A 180 cm (6 ft) long smooth bore tubing with integral end fittings (35 mm ID) for connection to the Gas Mixing Chamber and Face Mask.
Pack of 50 disposable droplet filters. Used in human respiratory experiments to remove water droplets from the air stream and protect against cross-contamination.
Contains desiccant material (silica gel) for removing water from a gas stream. It can be used multiple times and recharged by replacing the desiccant...
Douglas Bags (120 liters, pack of 60)
A pack of 60 Douglas Bags (120 liters), designed to hold expired air for respiratory studies.
The In-line Filter connects directly to the sampling port of the Gas Analyzer to protect the transducers from moisture and damaging particulates.
Calibration Syringe (3L, 35mm outer diameter/28.6mm inner diameter outlet)
Provides an easy and reliable method of calibrating respiratory equipment.
End cap (Red, R-series, pack of 100)
Used with the One-Way Valve Mouthpiece to prevent any air leakage when used in conjunction with the Douglas Bags.
This is a pack of 50 disposable nose clips used to clamp the nostrils comfortably while making respiratory measurements.
The SpO2 Ear and Finger Clips are designed to measure oxygen saturation. They are approved for human use and supplied with the appropriate Oximeter Pod.
Engineered for precise, consistent, reliable data acquisition of a wide range of physiological signals. PowerLab gives you the reproducible data you need while meeting the strictest international standards.
Creates a platform allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots.
Hypoxia studies
Respiratory disease studies e.g. COPD, asthma, emphysema, cystic fibrosis
Allergen/inflammation studies
Sports Research
The simultaneous measurement of respiratory gas concentrations and airflow with our metabolic systems permits the calculation of the following metabolic parameters.
Temperature is a useful tool in determining many factors such as subject health or the stability of an experimental preparation. It is also usefulas a calculation factor for comparing measurements taken in different states.
ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart analysis software and a PowerLab data acquisition unit you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.
Enabling Discovery
LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.
Data with Integrity
High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.
LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.
Respiratory Gas Analysis using the Exercise Physiology System and the Metabolic Add-On for LabChart.
RER is calculated by dividing VCO2 by VO2, therefore if the VCO2 is higher than expected but the VO2 is normal, this would explain the high RER. Alternatively, if the VCO2 is normal, but the VO2 seems low, this would also explain the high RER. In either case, the raw CO2 and O2 values should be assessed by recording known concentrations of each to make sure these are calibrated correctly. If the CO2 and O2 values are not contributing to the high RER, the flow calibration should be checked. Other factors that might cause a high RER are subject panting/breathing uncomfortable once the face mask is attached creating a higher than normal CO2 output. Another common problem can be air leaks, either from around the face mask which must be completely air tight, or within the breathing circuit.
×Additional acquisition and analysis features and add-ons to support your Respiratory Gas Analysis studies:
In this module you can easily calculate and display ventilatory parameters such as VCO2, VO2, VE and RER online from measurements of %O2, %CO2 and air flow.
Metabolic
MLS240/8
Derive multiple respiratory parameters from recorded flow and generate easy-to-read spirometry reports.
Spirometry
Free download
Simultaneously record and synchronize video in your LabChart data file. Replay to observe video and physiological data together.
Video Capture
MLS320/8
With this app you can stop and start recording and add comments or macros from your iPhone or iPad, so you don't have to be tethered to your computer during recording.
LabChart Remote
Free download
Share your data in the cloud or publish online for peer review the moment you finish recording or complete an experiment. You can also embed an interactive data panel with signals online, just like the example below. Learn more about LabChart Online or login.
LabChart Online
Mountain Lab- Studying the effects of stress and extreme conditions on human physiology
A special one hour webinar looking at the effects of tilt, exercise and high altitude on human...
This video demonstrates how to use the Gas Analyzer to measure respiratory gas concentrations...
Thank you for your interest in Respiratory Gas Analysis. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
×Thank you for your interest in Respiratory Gas Analysis. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.
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