… used in the measurement and analysis of blood pressure regulation in physiology research. This event is chaired by Dr. Nina Stachenfeld and includes a presentation … blood pressure regulation in humans The benefits of solid-state sensors in small animal telemetry recording for data quality Abstract: Hypertension (high blood … – LabChart Software Demonstration » Data Collection & Analysis in Human Autonomic Research: How to Guide Successful Testing» Measuring and Quantifying …

… Physiologist and Senior Lecturer at the University of Auckland, whose pre-clinical research focuses on understanding blood pressure regulation in the brain in response … to life-threatening diseases like ischemic stroke. Through the use of small animal telemetry , she is able to perform long-term studies looking into the … selfish brain hypothesis. We believe that the brain, through its control of the autonomic nervous system, has the ability to modulate systemic blood pressure. And if …

… disease remains one of the leading causes of death worldwide and how research studies in large animals are vital to translating findings from research … The use of large animals allows chronic measurements of arterial pressure and blood flow which are not always possible in rodent models. These measurements allow a … re-located back to Auckland in 2014 where he is running his own lab investigating autonomic control of the circulation in ovine models of hypertension and heart …

… of the body via the spine and cranial nerves, tracking fluctuations and adjusting autonomic systems. Spinal cord injuries alter or sever that feedback mechanism and … a scientific journey that covers every step the team took from developing an animal model of autonomic dysreflexia through to testing a stimulator implanted in … including anomalous interactions contributing to clinical disorders, Aaron's research focuses on developing novel therapeutics for people with neurological health …

… PV Loops are the gold-standard method for assessing cardiac function in animal studies. The technique produces load-independent measurements of heart … and treatment models. It turns out, one of the greatest limits of pressure-volume research is the non-standardized approach to performing and publishing this research. … Occlusions should be brief (10–15 seconds) to avoid activating confounding autonomic reflexes. For systolic indices, three replicate inferior vena cava …

… Blood flow measurements offer us a clear picture of cardiovascular health.  The … transit-time technology for animals of all sizes. Transonic Flowprobes - Research Applications: Acute Renal Blood Flow in Rabbits Mesenteric Venous and Arterial Flow in Rats Fetal Cardiovascular Development in Sheep Autonomic Cardiovascular Control in Sheep   Acute Renal Blood Flow in Rabbits …

… specific focus on the Organ-Cultured Anterior Segment (OCAS) model using different animal species. Key Learning Objectives: An overview of Organ-cultured Anterior … Invasive Blood Pressure – fundamentals and best practices for preclinical research» Autonomic Blood Pressure with ADInstruments» How to Calibrate a Millar Catheter using …

… experts who are using Transonic fluid flow measurements in their perivascular research. This event offers a valuable platform for researchers to connect, exchange … from four researchers who currently use Transonic Systems in their small and large animal studies Address frequent research challenges such as surgery and placement of … Professor Rohit Ramchandra will discuss investigating chronic recordings of autonomic nerve activity and blood flow to various organs in large animal models. …

… Kevin O’Gallagher, PhD, discuss planning for success when translating preclinical research and the importance of building relationships with their clinical colleagues. … control in spinal cord injury patients Telemetry for long-term monitoring of animal models of hypertension, ischemic stroke, and diabetes Invasive and noninvasive … is an integrative cardiovascular physiologist focusing on the relationship between autonomic activity, blood pressure, and organ blood flow. Fiona's recent research …

… their diverse projects. Learn firsthand from researchers as they delve into their research projects and the telemeters they utilized. Discover the unique benefits of … Applications Using Kaha Science Telemetry  Three Simple Tips for Small Animal Telemetry Guest Speakers: Dr. Fiona McBryde, PhD Senior Research Fellow, … an integrative cardiovascular physiologist, delves into the intricate interplay of autonomic activity, blood pressure dynamics, and organ perfusion. Her recent …

… from researchers using Kaha telemeters. Kaha Sciences Telemetry – High-Impact Research: Naturalistic Variations in Intracranial Pressure Oxygen, Carbon Dioxide, … is a finite amount of room inside your skull. Changes in the amount of tissue, blood, or cerebrospinal fluid inside the skull alter the overall intracranial … technology, but we can get an idea of the kinds of events that impact ICP from animal studies. Eftekhari et al. explored long-term ICP fluctuations by recording …

… required in the areas that need them. The parallel activation of movement and the autonomic nervous system is driven by the central command, increasing breathing rate, heart rate, and blood pressure as well as motivating us to perform these energy-intensive movements. … needed to start their journey. “By introducing telemetry and optogenetics into our research programme,” Satoshi says, “we’ve been able to develop a research environment …

… living in their home cages without the use of tethers. The use of telemetry in animal research is a recommended industry practice for improved animal welfare. Using … ) telemeters were implanted in a single rat to simultaneously record arterial blood pressure, intracranial pressure, and brain tissue oxygen to investigate …

… insight into hypertension and thousands of other diseases that afflict humankind, animal models of human disease are frequently used. Due to the vast number of … required anaesthesia. However anaesthetics can have complex, biphasic effects on autonomic nervous system function, necessitating the use of indirect measures such as … hypertension, sympathectomy of the renal supply can substantially lower blood pressure. Mice were instrumented with an indwelling catheter containing a …

… technology to provide unrivaled accuracy and long-term recording in cardiovascular research. With options to measure pressure (arterial, venous, and ventricular), ECG, … also allows customers to combine  ECG  and  pressure  measurements from the same animal to assess cardiac and cardiovascular function. Publications: Kim, N. K., … SNA leads is ±60µV making it ideal for activity recording from fine, peripheral autonomic nerves. Publications: McBryde, F. D., Liu, B. H., Roloff, E. V., Kasparov, …

… practices to run their experiments. We’re witnessing a new wave of cutting-edge research using our fully implantable Kaha telemeters.  Below we highlight just a few … . Related: Getting started with small animal Telemetry: Fiona’s top three tips »   Heart rate variability is dissimilar to vagal tone The vagus nerve is the largest nerve in the autonomic nervous system, innervating the heart, lungs, and digestive system. The …

… Wheelchair Rugby Squad for 5 years during his Master’s and PhD, assessing their autonomic and cardiovascular performance on every scale he could, measuring the … up a postdoc position in Professor Andrei Krassioukov’s lab, moving toward small animal models of autonomic function and spinal cord injury to try and fill those … in Pressure-Volume Data Collection “I have a basic physiology arm to my research program now that just explores autonomic control of the heart under …

… group at the University of NSW highlights the many facets of psychophysiological research and reiterates the inherent relationship between psychological processes and … and an interest in physiology, Alex embarked to do honours in the field of autonomic dysreflexia, a dangerous and potentially fatal complication that often … by the researchers are below. Autonomic responses to acute infection From animal studies, it is well documented that stress-induced sympathetic activation …

… known as our Enteric Nervous System (ENS). The ENS is the largest component of our autonomic nervous system and is unique in the fact that it can function independently … that propagated along the whole colon, even though the colon was isolated from the animal. This amazed me in 1992 and still does today.”   Shining a light on the … the inner workings of the ENS.  What is optogenetics? Optogenetics is a modern research tool that allows neuroscientists to control the activity of neurons using …

… Ensure that the loop is close to the telemeter body as it will lie within the animal's body. The size of the loop will depend on the desired length of the fiber. … information and useful resources relating to optogenetics applications and research. If you have any questions, please contact your ADInstruments support … Page » Additional resources Optogenetic Activation of Selective Cardiac Autonomic Neurons (webinar) » Discover the Kaha Sciences Suite of products to set up …