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Why do I have limited menu icons for the PV loop module?

Support Article
… PV Loop version 2 saw the introduction of workflow for a step-by-step guide to Pressure … visible in the tool bar.  When the workflow is complete, all of the icons for the PV loop module will be visible and available for use. If you wish to use the module …
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Does PV Loop support the regression parameters in PVAN's regression file?

Support Article
… PV Loop calculates most of these parameters, but because the regression equations are in … a parameter that is calculated during a time-varying elastance  analysis , however PV Loop doesn't currently perform this type of analysis.   (If you think this would be a …
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How can I apply an Alpha Correction using PV Loop Workflow?

Support Article
… performed after the cuvette and saline calibration steps, which will match the PV-Loop module's calculated values to a reference source. You can calculate the alpha … by dividing the cardiac output (CO) or stroke volume (SV) recorded by the  PV Loop Module  by CO or SV measurements from another source such as aortic flow …
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How can I edit the PV loop view for publishing purposes?

Support Article
… Loop View displays the detected pressure volume loops as an XY line graph of pressure … to remove loops from the analysis by unchecking the box next to the required loop number:     These loops will then turn to a light grey to show they have been … example, make sure the plot is the active window in LabChart and choose Edit>Copy PV Loop Loop View... In Microsoft Word, choose Paste Special and choose the Windows …
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Can the ADInstruments PV-Loop Module be used with an admittance catheter system?

Support Article
… Although the PV Loop Module is intended for use with a Millar Pressure-Volume System (MPVS) based on … system are properly calibrated, data can be acquired in Step Four of the PV-Loop workflow.                                           Steps Five through Seven …
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How can maximal elastance (Emax) be calculated with the PV Loop Module?

Support Article
… occlusion. Then, select your occlusion data and analyze your selection with the PV Loop Module. Simply use the Loop View and make sure ESPVR is checked. The equation will be something like this:  …
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Why is the PV Loop Module unable to draw an exponential EDPVR line?

Support Article
… pressure values. It is recommended to perform a new LV pressure calibration. The PV Loop module should then able to draw the exponential EDPVR line. For further …
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What PV loop techniques can be used with the MPVS Duo?

Support Article
… or admittance techniques.   The MPVS Duo's guided workflow alongside LabChart's PV Loop Module allows the user to switch between techniques and analyze the resulting …
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Why aren't my analysis and plotting features showing in the PV Loop Module drop down menu?

Support Article
… You may notice that your PV-Loop Module dropdown menu needs key analysis options added.  As shown below, the …                     This is expected behavior when using the Workflow Mode of the PV-Loop Module .  The analysis plotting features in the PV Loop Module   will   only …
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How can I measure the time the heart spends in Systole and Diastole using the LabChart PV Loop Module?

Support Article
… It is possible to use information provided by the PV Loop Module to calculate the time that the heart spends in systole and diastole for … some additional setup is required.  A link to a LabChart file that uses the PV Loop Module , Cyclic Measurements Channel Calculation, and Arithmetic Channel …
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Why is the End Diastolic Pressure Volume Relationship (EDPVR) not present in the PV Loop Module's Hemodynamics Table?

Support Article
… When LabChart's  PV Loop Analysis Module is set to use Sinusoidal Pressure Fit for End Systole detection … Table.   You can, however, still gain information about EDPVR within the PV Loop Module. In the Loop View graph, you have the option to display the ESPVR and  …
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Why are values for the same hemodynamic parameters different in the Blood Pressure Module and PV-Loop Module analyses?

Support Article
… and will affect all of the calculations for these modules to some degree. The PV Loop Module uses a 2-point derivative calculation method , which is the same method used by Millar Instruments' PVAN software. This is to ensure that the PV Loop Module's results will match results previously obtained with the PVAN …
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Why is the end systolic volume (ESV) larger than the end diastolic volume (EDV) in the PV-Loop Module's Hemodynamics table?

Support Article
… This temporally mis-aligns the pressure and volume data, and causes the LabChart PV-Loop Module to incorrectly identify the EDV and ESV values. For further technical …
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Where can I learn more about the surgical, data acquistion, and data analysis techniques used in Pressure-Volume loop experiments?

Support Article
… Video Series  HERE  covers many surgical procedures needed for Pressure Volume (PV) and Invasive Pressure studies. The Millar Knowledge Center, accessed HERE , is a great resource for learning the background of the Pressure-Volume (PV) loop experiment and surgical and analysis techniques. It is free to use and only …
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Can the Millar MPVS Ultra system be used to record PV data from the right ventricle in small and large animals?

Support Article
… growing number of researchers are studying  right ventricle (RV) pressure volume (PV) loops with the Millar MPVS Ultra system  in both small and large animals. Because RV PV is a relatively new area of research, there are a limited number of publications … left ventricle (LV) loops, ADInstruments introduced two new algorithms into the PV Loop Module 2.5 . These new algorithms provide improved, automatic detection of …
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When recording PV-Loop data, why is the subject's pressure signal and heart rate lower than expected?

Support Article

The animal is either over-anesthetized or has lost too much blood during the course of the surgical procedure. Adjust the anesthesia concentration and/or dosage, or choose a more appropriate anesthetic agent. Minimize blood loss during surgery by...

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How is aortic stenosis characterized by left ventricle pressure volume loops?

Support Article
… the contraction's force to maintain stroke volume.  Aortic stenosis will cause PV loops to shift up and to the right.   For further technic al assistance with this …
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What catheter volume segment length do I use for particular animal models with the Millar MPVS Duo?

Support Article
… Millar MPVS Duo interface. The segment being used will be displayed on the “New PV Loop Protocol: Optimize Catheter Position” screen shown below.     A Ventri-Cath … that span different ventricular scenarios.      If you see an odd shape in your PV loops, the most likely reason is if the volume sensing segment is not placed …
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Can I use the Rho Cuvette with my MPVS Duo?

Support Article
… using Bahn’s equation, which will require the Rho value to be entered into the PV workflow in LabChart's PV Loop Module to get a suitable readout that was previously applied in the MPVS Ultra …
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What does the Millar Manufacturer Warranty for Mikro-Tip Catheters cover?

Support Article
… Out of Box Failure Millar guarantees Mikro-Tip™ Pressure and Pressure-Volume (PV) Loop catheters will function within specification at first use within thirty (30) … to the customer. Manufacturer Warranty Mikro-Tip™ Pressure and Pressure-Volume (PV) Loop catheters are protected by a limited manufacturer warranty. Millar warrants …

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