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  • Blog (27)
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video

Webinar | Cardiac Energetics at the Working-Heart Level: Leveraging PV Loops for Efficiency

Video
… Bioengineering Institute, our team has constructed an experimental device (work-loop calorimeter) that enables measurement of cardiac efficiency at the tissue … and Operating your Radnoti Working Heart System Ventricular Pressure Volume + PV Loops Guest Speakers: Image Above: Esau Mhandu (left) and Dr. June-Chiew Han … measurement include working-heart rig (ex vivo heart experiments) and work-loop calorimetry (in vitro tissue experiments).   Esau Mhandu PhD Candidate …
Image

Watch webinar: Cardiac Pressure-Volume Loop Data Analysis - Tips & Tricks

Blog
… In this free on-demand webinar, PV loop experts DeWayne Townsend (DVM, Ph.D.) and Adam Goodwill, (Ph.D.) discuss how to collect and analyze high-quality pressure-volume loop data. …
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What does the Millar Manufacturer Warranty for Mikro-Tip Catheters cover?

Support Article
… Out of Box Failure Millar guarantees Mikro-Tip™ Pressure and Pressure-Volume (PV) Loop catheters will function within specification at first use within thirty (30) … to the customer. Manufacturer Warranty Mikro-Tip™ Pressure and Pressure-Volume (PV) Loop catheters are protected by a limited manufacturer warranty. Millar warrants …
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What are the volumes of the Millar small animal Dip-well Cuvettes and why do they vary depending on the catheter I use?

Support Article
… When calibrating the volume of small animal PV catheters, you'll use one of two cuvette models: the 910-1048 (11 wells) or the … are available: For the 910-1048 For the 910-1049 If you're using the ADInstruments PV Loop Module for LabChart 7 or higher, it includes settings files that pre-populate …
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How can multiple analysis settings for LabChart Analysis Modules be saved in a Data File?

Support Article
… with LabChart Modules ( Blood Pressure , ECG Analysis , HRV , Peak Analysis , PV Loop , and Spike Histogram ) to save the module settings associated with one or more …
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Why are some of my menu items greyed out on the MPVS Duo?

Support Article
… out. This will generally depend on some previous actions. A summary is below: ‘New PV loop protocol’ should only be grey if the catheter is not detected. If a catheter is …
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Which model of the Ventri-Cath catheter is most suitable for my animal model?

Support Article
… each model can be used for. Note, this distance can be dynamically adjusted during PV loop procedures to match individual ventricular axis in the MPVS Ultra control …
image

Cardiac Energetics at the Working-Heart Level: Leveraging PV Loops for Efficiency

Event
… Bioengineering Institute, our team has constructed an experimental device (work-loop calorimeter) that enables measurement of cardiac efficiency at the tissue … and Operating your Radnoti Working Heart System Ventricular Pressure Volume + PV Loops Guest Speakers: Image Above: Esau Mhandu (left) and Dr. June-Chiew Han … measurement include working-heart rig (ex vivo heart experiments) and work-loop calorimetry (in vitro tissue experiments).   Esau Mhandu PhD Candidate …
Image

Understanding the Importance of PV Catheter Calibration in Admittance and Conductance Systems

Blog
… Transcript Pressure-Volume (PV) Loops are the gold standard for measuring direct, real-time cardiac function. There are two technologies available for doing PV loop studies, admittance and conductance. Both systems call for calibration …
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What is the manufacturer warranty period for Millar products?

Support Article
… is outside of this 3-year repair window, your catheter cannot be repaired. PV-Loop and Pressure control units do not fall under this 3-year repairable window, and …
Image

Pressure-volume catheter placement in the left ventricle - Carotid vs. Apical approach

Blog
… Ventricular pressure-volume (PV) relationships are a well established and comprehensive means for assessing … miniaturization of catheters and optimization of surgical procedures, ventricular PV analysis has successfully been translated to small rodents, opening up the … is the best surgical approach for your PV research. For more information about PV loop data acquisition and analysis, check out Dr. DeWayne Townsend and Dr. Adam …
A blue tile with the words 'Standardizing Pressure-Volume research for more reliable outcomes', an image of a pv loop, and a photo of dr oliver wearing

Standardizing Pressure-Volume research for more reliable outcomes

Blog
… PV Loops are the gold-standard method for assessing cardiac function in animal … has an influence on the interpretation of the end Image Points on the PV Loop. results, limiting the potential impact of each experiment, complicating our …
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What does the end diastolic pressure volume relationship (EDPVR) tell me on set of pressure volume loops?

Support Article
… and an increase in compliance might be related to a dilated cardiomyopathy.   PV Basics.pdf Am J Physiol Heart Circ Physiol-2005-Burkhoff-H501-12.pdf For further …
Image

Getting to the heart of the problem: Understanding the causes of cardiac hypertrophy

Blog
… drug targets and therapies for treating the disease 3,4,5 .  The power of the PV Loop - A visual representation of disease progression  Min regularly uses  ventricular pressure-volume (PV) analyses to characterize and study cardiac hypertrophy. PV Loops are generated by …
video

Webinar: Measurement of Cardiac Function Using Pressure-Volume Loops in Swine

Video
… to catheterize the left ventricle Which catheter/sheath options are available for PV catheter introduction What to expect when performing left ventricle PV loop analysis Abstract: Translational models are extremely important for testing …
video

Calibration Walkthrough for PV using Echo

Video
… complete cardiac function, particularly myocardial contractility measurements. The PV Loop Analysis Module in LabChart 8 offers smart presets for different animals and … workflows guiding you step-by-step from calibration through to analysis. If using PV Loop version 2.3 or above, you can make use of your echocardiogram unit in PV Loop …
image

A Webinar on PV Loop

Event
… ADInstruments is pleased to invite you to our upcoming Webinar on PV loop webinar with Daniel Donner and Aascha Brown from the Baker Institute.  Date: …
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What calibration parameters do I use in Admittance Mode with the Millar MPVS Duo?

Support Article
… the screen prompts users to enter the calibration parameters for the admittance PV Loop Protocol, as shown below.   The Millar MPVS Duo requires three study parameters …
Image

New Release: LabChart 8.1.11

Blog
… correction due to invalid volume data  to even the rarest of cases, with ease. PV Loop 2.4.1 Release We've optimized the PV Loop echo volume calibration so that it accurately calculates ESV and EDV values …
MPVS Duo blog tile

The Best of Both Worlds - The MPVS Duo from Millar

Blog
… The MPVS Duo is an intuitive pressure-volume loop measurement system from Millar.  Designed to work in conjunction with Millar’s gold-standard Mikro-Tip PV Duo catheters for the perfect combination of ease and accuracy, so you can carry … you interpret more transparent. One System for All Animal Models Millar Mikro-Tip PV Duo catheters range from 1F to 5F, enabling pressure-volume measurements to be …

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