PV Loop 2.5 Update

Web video URL

Great news! LabChart’s latest version of the PV Loop Analysis Module includes new features designed to give you precise and accurate measurements of right and left ventricular contractility in small and large animal models. 

In version 2.5, we have added two new algorithms for detecting end-systole in both right and left ventricular PV loops, and in situations where your PV loop may take on a more 'triangular' shape.

The PV Loop Analysis Software Module for LabChart is specifically designed for the analysis of in vivo ventricular pressure-volume data in small and large animals, or ex vivo, using working heart systems. Analyze ventricular pressure-volume baseline and occlusion data in realtime or post-acquisition.

More about the PV Loop Module »

What's new in PV Loop 2.5?

  • Added a new single-beat detection method ‘Sinusoidal pressure fit’.
  • Added single-beat ESPVR (end-systolic pressure-volume relationship) into the hemodynamics table.
  • Added single-beat Piso (max pressure of an isovolumic beat) into the hemodynamics table.
  • Added a new ‘Loop tangent fit’ method for calculating ESPVR and the End Systolic points from multiple beats during occlusions.

Note: the Sinusoidal pressure fit’ and ‘Loop tangent fit’ methods are especially useful for right ventricle measurements and other situations where the PV loop has a ‘triangular’ shape.

How to download PV Loop 2.5

You can download the PV Loop Module using LabChart's Feature Manager, or on our website: PV Loop 2.5 for Windows.

System Requirements

 PV Loop 2.5 is only compatible with LabChart v8.1.13 or later.

Want to know more?

Find out more about the PV Loop Analysis Module and the new features by visiting the PV Loop help in LabChart or check out the links below:

Additional resources:

Tips and Tricks for measuring pressure-volume loops in mice »

Introduction to PV loops: Understanding points on the PV loop and measures of cardiac function »

Catheter placement in the left ventricle – Carotid vs. Apical approach »

Understanding ventricular pressure-volume catheter calibrations and experimental design »

Related products