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Ventricular Pressure Volume

Ventricular Pressure Volume

Changes in ventricular function for both normal and diseased conditions can be studied through analysis of ventricular pressure volume loops. The gold standard method for measuring direct, real-time complete cardiac function, particularly myocardial contractility measurements, PV loops can be generated by plotting real-time left ventricular pressure against left ventricular volume during a complete cardiac cycle.

Providing instant cardiovascular function feedback based on morphology, position and timing of the loop, ventricular pressure volume is the only research technique that provides you full diastolic analysis and allows you to vary the load and measure beat-to-beat response of that changing load in cardiac performance.

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Ventricular Pressure Volume

Products and Solutions

Gold standard<br />
catheters

Gold standard
catheters

Begin with a<br />
foundation system<br />
and build from there

Begin with a
foundation system
and build from there

Mix and match<br />
products for a<br />
custom solution

Mix and match
products for a
custom solution

Integrate all<br />
your data streams<br />
in one place

Integrate all
your data streams
in one place

We are  proud to be exclusive global distributors of Millar Mikro-Tip®  pressure catheters and associated hardware for ventricular pressure volume recording. By combining these highly sensitive, minimally invasive  catheters with the power and integrity of PowerLab data acquisition and LabChart data analysis software, you can be sure you’ll get results you can trust.

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In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of events in LabChart. So you have even more flexibility and can integrate all your data streams in one place.

All of our hardware recommended for human use is backed by the appropriate safety certification standards. More information on safety standards.

Foundation Systems

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Components & Related Products

Typical Ventricular Pressure Volume Studies

Systolic and diastolic dysfunction

Pulmonary hypertension

Cardiac hypertrophy

Cardiac failure

Cardiovascular remodelling and vascular occlusions

Pharmacology / toxicology studies

Transgenic manipulation

Ischemia / Reperfusion studies

Gene manipulations

Cardiac resynchronization therapy

Surgical interventions

Signals Supported

dP/dT
+

dP/dt is a signal derived from pressure, typically ventricular blood pressure, that indicates the change in pressure over time.

Products related to dP/dT and Ventricular Pressure Volume

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ECG
+

Millar Mikro-Tip PV catheters are also able to measure intercardiac ECG from the MPVS Ultra System when placed inside the left ventricle of an animal. The peak of the R wave aligns with end-diastolic pressure in the left ventricle which may be used to enhance the analysis settings of LabChart’s PV Module.

Products related to ECG and Ventricular Pressure Volume

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Pressure
+

Accurately measure continuous real-time left ventricular blood pressure directly and simultaneously with left ventricular volume .  at the source using a range of Millar Mikro-Tip PV catheters and system options. With PV loop analysis a wide array of hemodynamic parameters can be gathered for assessment of complete cardiac function.

Products related to Pressure and Ventricular Pressure Volume

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Volume
+

Accurately measure continuous real-time left ventricular blood volume directly and simultaneously with left ventricular pressure  at the source using a range of Millar Mikro-Tip PV catheters and system options. With PV loop analysis a wide array of hemodynamic parameters can be gathered for assessment of complete cardiac function. 

Products related to Volume and Ventricular Pressure Volume

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Flexible Data Acquisition

ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart analysis software and a PowerLab data acquisition unit you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

LabChart

Enabling Discovery

LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.

LabChart and Ventricular Pressure Volume

PowerLab

LabChart

Data with Integrity

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.

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All your Ventricular Pressure Volume analysis in one place

LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.

  • Inferior vena cava (IVC) occlusion data from a rat featuring the Loop View, PRSW Plot, and Hemodynamics Table from LabChart’s PV Loop Analysis Add-On.

    Inferior vena cava (IVC) occlusion data from a rat featuring the Loop View, PRSW Plot, and Hemodynamics Table from LabChart’s PV Loop Analysis Add-On.
  • Real time monitoring of Ventricular Pressure and Volume signals, Arterial pressure, and dP/dt calculated using cyclic measurements

    Real time monitoring of Ventricular Pressure and Volume signals, Arterial pressure, and dP/dt calculated using cyclic measurements
  • An IVC occlusion, featuring typical analysis plots such as Preload-recruitable stroke work and Afterload dependent mechanical work

    An IVC occlusion, featuring typical analysis plots such as Preload-recruitable stroke work and Afterload dependent mechanical work

Features and Add-Ons

Additional acquisition and analysis features and add-ons to support your Ventricular Pressure Volume studies:

Caring for your Millar Mikro-Tip® Catheters

Millar Mikro-Tip Catheters require a certain level of care to ensure accuracy and the anticipated lifespan of your catheters. For a few best practice tips to help get you started with your catheters, see our guide here.

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Ventricular Pressure Volume Data in LabChart

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Citations

3,900 papers

in Ventricular Pressure Volume on Google Scholar cite ADInstruments.

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Thank you for your interest in Ventricular Pressure Volume. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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Thank you for your interest in Ventricular Pressure Volume. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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