Isolated Tissue Baths

Isolated Tissue Baths

Isolated tissue baths are used to maintain the integrity of muscle tissue for several hours, in a controlled environment, while physiological measurements are performed.

Controlling conditions like temperature, oxygenation, nutrients and pH is a useful way to observe and compare evoked responses to drugs and electrical stimulation. The tissue responds to the stimuli by contracting or relaxing, and an isometric or isotonic transducer is used to measure force or displacement, respectively. A wide a variety of tissue from various species can be studied, including chick, toad, rabbit, rat, mouse and guinea-pig.

PowerLab and LabChart, combined with a tissue bath apparatus, provide a simple, sophisticated solution for Isolated Tissue Research.

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Isometric contraction analysis of a toad rectus muscle to the presence of acetylcholine and suxamethonium using Dose Response Module

Products and Solutions

Record multiple
signals at one time

Simple, streamlined systems
you can build upon

Mix and match products for a custom solution

Integrate all your
data streams
in one place

In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of the event in LabChart, giving you even more flexibility and the ability to integrate your data streams in one place.

All our hardware is backed by the appropriate safety certification standards. More information on safety standards.

Complete System

Panlab Organ Bath Systems

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Panlab multi-chamber Organ Bath Systems combine modular PowerLab data acquisition system options, LabChart software, and measuring instruments (Bridge Amplifier, Isometric Transducer) with a...

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Panlab Organ Bath Systems

RSBPAN004/C, RSBPAN008/C, RSBPAN016/C

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Radnoti 4 Chamber Tissue-Organ Bath System

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A highly modular and comprehensive research system for simultaneously measuring and analysing isometric force from 4 isolated tissues. Combines a Front End Interface, Bridge Amp, Isometric Transducers and LabChart with a Radnoti 4 Chamber Tissue-Organ Bath Apparatus.

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Radnoti 4 Chamber Tissue-Organ Bath System

RSBRAD504/C

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Radnoti 8 Chamber Tissue-Organ Bath System

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A highly modular and comprehensive research system for simultaneously measuring and analysing isometric force from 8 isolated tissues. Combines a PowerLab C, Front End Interface, Bridge Amp, Isometric Transducers and LabChart with a Radnoti 8 Chamber Tissue-Organ Bath Apparatus. Includes a Radnoti 4 to 8 Chamber Conversion Kit.

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Radnoti 8 Chamber Tissue-Organ Bath System

RSBRAD508/C

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Radnoti 16 Chamber Tissue-Organ Bath System

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A highly modular and comprehensive research system for simultaneously measuring and analysing isometric force from 16 isolated tissues. Combines a PowerLab C, 2 x Front End Interfaces, Bridge Amp, Isometric Transducers and LabChart with a Radnoti 16 Chamber Tissue-Organ Bath Apparatus. Includes a Radnoti 4 to 8 Chamber Conversion Kit.

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Radnoti 16 Chamber Tissue-Organ Bath System

RSBRAD516/C

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Components & Related Products

Typical Studies using Isolated Tissue Baths

Pharmacological discovery studies

Determining the effects of drugs

Drug therapy studies

Molecular modeling of drugs

Pharmacological dissection of cell function

Muscle fatigue and performance

Isolated tissue experiments and research

In vitro tissue response

Signals Supported

Electrical Stimulation

Measure electrical stimulation and pacing for your in vitro research.

Fluid Flow

Fluid flow can be recorded in isolated tissue and organ research.

Force

Force can be measured in isolated tissue and organ research.

Temperature

Temperature is a useful tool in determining many factors such as subject health or the stability of an experimental preparation. It is also usefulas a calculation factor for comparing measurements taken in different states.

Flexible Data Acquisition

ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart or LabChart Lightning analysis software and a PowerLab data acquisition unit, you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

Enabling Discovery

LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds. Learn more about LabChart and Isolated Tissue Baths »

LabChart Lightning

Data acquisition and analysis re-imagined. Make unique discoveries with unlimited freedom and flexibility. Try LabChart Lightning »

PowerLab

Data with Integrity

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards. Learn more »

PowerLab C

PowerLab C

Re-engineered for
unparalleled flexibility

A modular data acquisition foundation system that provides unparalleled flexibility for researchers looking to invest in customizable, reliable solutions for both now, and in the future. Learn more »

All your analysis in one place

LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.

Isometric contraction analysis of a toad rectus muscle to the presence of acetylcholine and suxamethonium using Dose Response Module

Pro Tip

Pro Tip: Important principles to observe when performing tissue bath experiments.

Features and Add-Ons

Additional acquisition and analysis features and add-ons to support your Isolated Tissue Baths studies:

LabChart Lightning

Data acquisition and analysis re-imagined.

Make unique discoveries with unlimited freedom and flexibility.

Try LabChart Lightning now for free

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Citations

4480 papers

in Isolated Tissue Baths on Google Scholar cite ADInstruments.