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  • Blog (27)
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Image

Introduction to PV loops: Understanding points on the PV loop and measures of cardiac function

Blog
… Pressure-volume (PV) loops are the gold standard for measuring direct, real-time cardiac function. By … simultaneously plotting real-time ventricular pressure against ventricular volume, PV loops provide a unique, quantitative approach for determining the contractility of … University School of Medicine, provides a comprehensive introduction to the PV loop, how it compares to other techniques, and tips for interpreting measures of …
video

PV Loop 2.5 Update

Video
… Great news! LabChart’s latest version of the PV Loop Analysis Module includes new features designed to give you precise and accurate … two new algorithms for detecting end-systole in both right and left ventricular PV loops, and in situations where your PV loop may take on a more 'triangular' shape. …
pressure volume loop labchart

PV Tips and Tricks: Expert advice for measuring pressure-volume loops in mice

Blog
… Variability in your pressure-volume (PV) measurements can be introduced at any stage of the experiment, from your catheter … your experimental design, plus handy tips and tricks for collecting high-quality PV loop data. Overview Fluid management   - Blood loss and insensible fluid loss …
video

Optimizing Preclinical PV Loop Techniques and Analysis in Mice

Video
… started with Pressure-Volume acquisition and analysis, or those already using PV Loops who may benefit from tips on increasing throughout and experimental … connection and setup; through to an introduction to the Labchart workflow for PV and how to optimize workflow from acquisition of PV Loops to how to analyze them … to PV assessments: Including compliance and inotropy / interpreting the loop Surgical procedure setup: Including preparation tips, equipment setup and …
video

Cardiac PV Loop Data Analysis: Tips & Tricks (Webinar)

Video
…   This is a useful webinar for cardiovascular researchers who currently use PV Loops and would like to improve, or those who are interested in exploring PV loops for future cardiovascular research. Abstract: During this session, PV loop experts DeWayne Townsend, DVM, PhD and Adam Goodwill, PhD discuss how to collect …
Four catheters and the title 'Should you be using admittance or conductance calibration for PV Loops?'

Should you be using Admittance or Conductance calibration for PV Loops?

Blog
… Pressure-volume (PV) loops are the gold standard for measuring direct, real-time cardiac function. By … simultaneously plotting real-time ventricular pressure against ventricular volume, PV loops provide a unique, quantitative approach for determining the contractility of … measurement forms the basis for the volume measurement.  Image A pressure-volume loop graphs pressure against volume within the ventricle to produce a …
2024-Chris West Heart Spine PV Loop

Associate Professor Chris West: The heart, the spine, and the PV loop

Blog
… performance from the load on the heart. This is the reason Chris and his team use PV loops. Related: Introduction to PV loops: Understanding points on the PV loop and measures of cardiac function “With typical cardiac measures you have to ask …
video

Calibration and Setup of your MPVS Ultra (using PV Loop module)

Video
… animals large and small. Proper configuration is paramount to running a successful PV experiment. Join David as he discusses the proper steps for configuring a typical … hardware and software setup using the multisegment catheters, cables and Ultra PV system. David will also discuss how to properly use the built-in volume … techniques using Rho cuvette and Baan’s equation. Utilizes the specialized PV Loop Analysis Module in LabChart.    Click here for information on the MPVS Duo >> …
Image

Keeping Cardiovascular Researchers in the Loop: Why studying pressure-volume loops could be useful for you...

Blog
… researcher? Find out why you should consider studying ventricular pressure-volume (PV) loops - the gold standard for measuring direct, real-time cardiac function. Why study PV Loops? Pressure-volume loops are the gold standard for measuring direct, real-time … severity, prognosis and response to therapies in patients with PH.   Analyzing PV Loop data - The problem with right ventricular PV loops Analyzing PV loop data is …
video

Webinar | Cardiac Energetics at the Working-Heart Level: Leveraging PV Loops for Efficiency

Video
… Bioengineering Institute, our team has constructed an experimental device (work-loop calorimeter) that enables measurement of cardiac efficiency at the tissue … and Operating your Radnoti Working Heart System Ventricular Pressure Volume + PV Loops Guest Speakers: Image Above: Esau Mhandu (left) and Dr. June-Chiew Han … measurement include working-heart rig (ex vivo heart experiments) and work-loop calorimetry (in vitro tissue experiments).   Esau Mhandu PhD Candidate …
Image

Watch webinar: Cardiac Pressure-Volume Loop Data Analysis - Tips & Tricks

Blog
… In this free on-demand webinar, PV loop experts DeWayne Townsend (DVM, Ph.D.) and Adam Goodwill, (Ph.D.) discuss how to collect and analyze high-quality pressure-volume loop data. …
Image

Understanding the Importance of PV Catheter Calibration in Admittance and Conductance Systems

Blog
… Transcript Pressure-Volume (PV) Loops are the gold standard for measuring direct, real-time cardiac function. There are two technologies available for doing PV loop studies, admittance and conductance. Both systems call for calibration …
Image

Pressure-volume catheter placement in the left ventricle - Carotid vs. Apical approach

Blog
… Ventricular pressure-volume (PV) relationships are a well established and comprehensive means for assessing … miniaturization of catheters and optimization of surgical procedures, ventricular PV analysis has successfully been translated to small rodents, opening up the … is the best surgical approach for your PV research. For more information about PV loop data acquisition and analysis, check out Dr. DeWayne Townsend and Dr. Adam …
A blue tile with the words 'Standardizing Pressure-Volume research for more reliable outcomes', an image of a pv loop, and a photo of dr oliver wearing

Standardizing Pressure-Volume research for more reliable outcomes

Blog
… PV Loops are the gold-standard method for assessing cardiac function in animal … has an influence on the interpretation of the end Image Points on the PV Loop. results, limiting the potential impact of each experiment, complicating our …
Image

Getting to the heart of the problem: Understanding the causes of cardiac hypertrophy

Blog
… drug targets and therapies for treating the disease 3,4,5 .  The power of the PV Loop - A visual representation of disease progression  Min regularly uses  ventricular pressure-volume (PV) analyses to characterize and study cardiac hypertrophy. PV Loops are generated by …
video

Webinar: Measurement of Cardiac Function Using Pressure-Volume Loops in Swine

Video
… to catheterize the left ventricle Which catheter/sheath options are available for PV catheter introduction What to expect when performing left ventricle PV loop analysis Abstract: Translational models are extremely important for testing …
video

Calibration Walkthrough for PV using Echo

Video
… complete cardiac function, particularly myocardial contractility measurements. The PV Loop Analysis Module in LabChart 8 offers smart presets for different animals and … workflows guiding you step-by-step from calibration through to analysis. If using PV Loop version 2.3 or above, you can make use of your echocardiogram unit in PV Loop …
Image

New Release: LabChart 8.1.11

Blog
… correction due to invalid volume data  to even the rarest of cases, with ease. PV Loop 2.4.1 Release We've optimized the PV Loop echo volume calibration so that it accurately calculates ESV and EDV values …
MPVS Duo blog tile

The Best of Both Worlds - The MPVS Duo from Millar

Blog
… The MPVS Duo is an intuitive pressure-volume loop measurement system from Millar.  Designed to work in conjunction with Millar’s gold-standard Mikro-Tip PV Duo catheters for the perfect combination of ease and accuracy, so you can carry … you interpret more transparent. One System for All Animal Models Millar Mikro-Tip PV Duo catheters range from 1F to 5F, enabling pressure-volume measurements to be …
catheter positioning blog tile

The Importance of Catheter Positioning in Pressure-Volume Data Collection

Blog
… Pressure-volume (PV) loop studies are the gold-standard for measuring direct cardiac function, providing … researchers can utilize XY View in Labchart to confirm the shape of their PV loop and aid in catheter placement. The challenges noted above can translate into …

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