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Isolated Organ

Isolated Organ

Isolated organ research allows for an organ to be studied in a controlled environment, free from external influences. Conditions such as temperature, the degree of oxygenation, available nutrients, and pH can be controlled for research purposes.

Perfusion of an organ - usually the heart, lungs, liver or kidney - may be required. Once the organ is successfully maintained outside the body, its physiological function can be studied via a whole suite of recordable parameters such as force, muscle contractions, pressure, and biopotentials.

ADInstruments offer a wide range of high-quality products, systems, and solutions to meet your isolated organ research needs, including a variety of tissue-organ bath systems. LabChart provides streamlined software to measure and analyze changes in blood pressure, flow, and volume, as well as many additional functions for pharmacological and cardiovascular research. We also offer a Dose Response Add-On, with analysis and graphical display of dose response data recorded in LabChart.

Analysis cardiovascular parameter from an isolated working heart experiment via Blood Pressure, Dose Response and Video Capture Modules

Products and Solutions

Record multiple<br />
signals at one time

Record multiple
signals at one time

Simple, streamlined systems<br />
you can build upon

Simple, streamlined systems
you can build upon

Mix and match products for a custom solution

Mix and match products for a custom solution

Integrate all your<br />
data streams<br />
in one place

Integrate all your
data streams
in one place

In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of the event in LabChart, giving you even more flexibility and the ability to integrate your data streams in one place.

All our hardware is backed by the appropriate safety certification standards. More information on safety standards.

Complete System

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Components & Related Products

Typical Isolated Organ Studies

Ischemia-reperfusion studies

Isolated tissue research

In vitro tissue response

Isolated organ drug studies

Hypertension studies

Heart modeling studies

Cardiovascular disease models

Signals Supported

dP/dT
+

dP/dt is a signal derived from pressure, typically ventricular blood pressure, that indicates the change in pressure over time.

ECG
+

Electrocardiography can be recorded for easy processing of heart rate, heart rate variability and similar functions.

Electrical Stimulation
+

Measure electrical stimulation and pacing for your in vitro research.

Fluid Flow
+

Fluid flow can be recorded in isolated organ research.

Force
+

Force can be measured in isolated organ research.

Heart Rate
+

Using pressure or electrical activity, monitor heart health by calculating heart rate.

pH
+

Measure pH with the ultimate working heart system and pH Amplifier.

Pressure
+

Measure parameters including perfusion/aortic pressure (afterload), dP/dt, Left ventricular pressure, left atrial pressure (preload) and developed pressure.

Temperature
+

Temperature is a useful tool in determining many factors such as subject health or the stability of an experimental preparation. It is also usefulas a calculation factor for comparing measurements taken in different states.

Volume
+

Measure volume of isolated organs.

Flexible Data Acquisition

ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart or LabChart Lightning analysis software and a PowerLab data acquisition unit, you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

LabChart

Enabling Discovery

LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds. Learn more about LabChart and Isolated Organ »

Data acquisition and analysis re-imagined. Make unique discoveries with unlimited freedom and flexibility. Try LabChart Lightning »

PowerLab

PowerLab

Data with Integrity

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards. Learn more »

PowerLab C

PowerLab C

Re-engineered for
unparalleled flexibility

A modular data acquisition foundation system that provides unparalleled flexibility for researchers looking to invest in customizable, reliable solutions for both now, and in the future. Learn more »

All your analysis in one place

LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.

  • Analysis cardiovascular parameter from an isolated working heart experiment via Blood Pressure, Dose Response and Video Capture Modules

    Analysis cardiovascular parameter from an isolated working heart experiment via Blood Pressure, Dose Response and Video Capture Modules

Using the Video Capture Module to record visual changes of the isolated heart.

In ischemic reperfusion studies, LabChart's Video Capture Module can be used to simultaneously record visual changes of the isolated heart - such as color and ischemic surface area changes -  in synch with other recorded parameters.

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Features and Add-Ons

Additional acquisition and analysis features and add-ons to support your Isolated Organ studies:

LabChart Lightning
LabChart Lightning
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Data acquisition and analysis re-imagined.

Make unique discoveries with unlimited freedom and flexibility.

Try LabChart Lightning now for free

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Thank you for your interest in Isolated Organ. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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Thank you for your interest in Isolated Organ. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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