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Isolated Organ

Isolated Organ

Isolated organ research allows for an organ to be studied in a controlled environment, free from external influences. Conditions such as temperature, the degree of oxygenation, available nutrients, and pH can be controlled for research purposes.

Perfusion of an organ - usually the heart, lungs, liver or kidney - may be required. Once the organ is successfully maintained outside the body, its physiological function can be studied via a whole suite of recordable parameters such as force, muscle contractions, pressure, and biopotentials.

ADInstruments offer a wide range of high-quality products, systems, and solutions to meet your isolated organ research needs, including a variety of tissue-organ bath systems. LabChart provides streamlined software to measure and analyze changes in blood pressure, flow, and volume, as well as many additional functions for pharmacological and cardiovascular research. We also offer a Dose Response Add-On, with analysis and graphical display of dose response data recorded in LabChart.

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Analysis cardiovascular parameter from an isolated working heart experiment via Blood Pressure, Dose Response and Video Capture Modules

Products and Solutions

Record multiple<br />
signals at one time

Record multiple
signals at one time

Simple, streamlined systems<br />
you can build upon

Simple, streamlined systems
you can build upon

Mix and match products for a custom solution

Mix and match products for a custom solution

Integrate all your<br />
data streams<br />
in one place

Integrate all your
data streams
in one place

In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of the event in LabChart, giving you even more flexibility and the ability to integrate your data streams in one place.

All our hardware is backed by the appropriate safety certification standards. More information on safety standards.

Complete System

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Components & Related Products

Typical Isolated Organ Studies

Ischemia-reperfusion studies

Isolated tissue research

In vitro tissue response

Isolated organ drug studies

Hypertension studies

Heart modeling studies

Cardiovascular disease models

Signals Supported

dP/dT
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dP/dt is a signal derived from pressure, typically ventricular blood pressure, that indicates the change in pressure over time.

Products related to dP/dT and Isolated Organ

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ECG
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Electrocardiography can be recorded for easy processing of heart rate, heart rate variability and similar functions.

Products related to ECG and Isolated Organ

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Electrical Stimulation
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Measure electrical stimulation and pacing for your in vitro research.

Products related to Electrical Stimulation and Isolated Organ

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Fluid Flow
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Fluid flow can be recorded in isolated organ research.

Products related to Fluid Flow and Isolated Organ

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Force
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Force can be measured in isolated organ research.

Products related to Force and Isolated Organ

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Heart Rate
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Using pressure or electrical activity, monitor heart health by calculating heart rate.

Products related to Heart Rate and Isolated Organ

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pH
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Measure pH with the ultimate working heart system and pH Amplifier.

Products related to pH and Isolated Organ

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Pressure
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Measure parameters including perfusion/aortic pressure (afterload), dP/dt, Left ventricular pressure, left atrial pressure (preload) and developed pressure.

Products related to Pressure and Isolated Organ

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Temperature
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Temperature is a useful tool in determining many factors such as subject health or the stability of an experimental preparation. It is also usefulas a calculation factor for comparing measurements taken in different states.

Products related to Temperature and Isolated Organ

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Volume
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Measure volume of isolated organs.

Products related to Volume and Isolated Organ

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Flexible Data Acquisition

ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart analysis software and a PowerLab data acquisition unit you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

LabChart

Enabling Discovery

LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.

LabChart and Isolated Organ

PowerLab

LabChart

Data with Integrity

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.

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All your Isolated Organ analysis in one place

LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.

  • Analysis cardiovascular parameter from an isolated working heart experiment via Blood Pressure, Dose Response and Video Capture Modules

    Analysis cardiovascular parameter from an isolated working heart experiment via Blood Pressure, Dose Response and Video Capture Modules

Using the Video Capture Module to record visual changes of the isolated heart.

In ischemic reperfusion studies, LabChart's Video Capture Module can be used to simultaneously record visual changes of the isolated heart - such as color and ischemic surface area changes -  in synch with other recorded parameters.

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Features and Add-Ons

Additional acquisition and analysis features and add-ons to support your Isolated Organ studies:

Isolated Organ Data in LabChart

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Request a demo

Thank you for your interest in Isolated Organ. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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Ask a question

Thank you for your interest in Isolated Organ. Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the contact page.

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