Langendorff

Langendorff Isolated Heart Perfusion

With the Langendorff isolated heart perfusion technique you can monitor an isolated heart while perfusing the coronary arteries with a nutrient solution. This allows you to record and  analyze multiple cardiac parameters such as left ventricular developed  pressure, perfusion pressure, cardiac electrical activity, heart rate and temperature all in real time.

ADInstruments' solutions support your use of the Langendorff animal heart perfusion technique to perfuse all sizes of heart models, from mice, rats, and guinea pigs, to porcine hearts.

Langendorff Heart

Products and Solutions

Record multiple<br />signals at one time

Record multiple
signals at one time

Compact and modular options available

Compact and modular options available

Mix and match products<br />for a custom solution

Mix and match products
for a custom solution

Integrate all your data<br />streams in one place

Integrate all your data
streams in one place

  • Perfuse all sizes of heart models hearts from mice, rats and guinea pigs, to porcine hearts
  • Choose from a compact system which utilises a peristaltic pump and STH pump controller for constant flow and pressure or more traditional modular system
  • Maintain constant temperature with a heater water bath, water jacketed tubing, components and heart chamber
  • Easily switch between constant-pressure and constant flow modes to investigate coronary artery function while the heart beats spontaneously or with the help of an external stimulator

In conjunction with our complete Langendorff perfusion systems shown below, any device with an analog output (+/- 10V) can be connected to a PowerLab data acquisition system for synchronization of event in LabChart. So you have even more flexibility and can integrate all your data streams in one place.

All of our hardware is backed by the appropriate safety certification standards. More information on safety standards.

Typical Studies
Isolated heart and organ perfusion
Medical device testing
Artificial heart development
Ischemia / Reperfusion studies
Pharmacology / toxicology studies
Myocardial function
Hypertrophy, infarction, cardiomyopathy and other disease models
Systemic circulation or ventricular studies
Coronary vessel function

Flexible Data Acquisition

ADInstruments systems provide an integrated solution to advance life science research. With the combination of LabChart or LabChart Lightning analysis software and a PowerLab data acquisition unit, you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

LabChart data analysis software creates a platform for all of your recording devices to work together, allowing you to acquire biological signals from multiple sources simultaneously and apply advanced calculations and plots as your experiment unfolds.

LabChart Lightning

Data acquisition and analysis re-imagined. Make unique discoveries with unlimited freedom and flexibility.

PowerLab

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.

PowerLab C

A modular data acquisition foundation system that provides unparalleled flexibility for researchers looking to invest in customizable, reliable solutions for both now, and in the future.

All your analysis in one place

LabChart software is designed specifically for life science data and provides up to 32 channels for data display and analysis options that are powerful and easy to use. With auto-recognition of ADI and LabChart Compatible hardware, multi-window views, one touch recording, simultaneous recording from multiple devices, specialized preconfigured settings, easy sharing options and an interface that can be customized to show only the features you want to use.

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Features and Add-Ons

Additional acquisition and analysis options to support your Langendorff analysis:

LabChart Lightning
LabChart Lightning
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Data acquisition and analysis re-imagined.

Make unique discoveries with unlimited freedom and flexibility.

Try LabChart Lightning now for free

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